Metabolic Dysfunction-associated Steatotic Liver Disease
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: SMART Diets for MASLD [Phase 2]
Phase 2 clinical trial update for SMART Diets targeting metabolic dysfunction-associated steatotic liver disease (MASLD); the study is not y…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Prevalence of Obesity in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
A registry entry describes a study on the prevalence of obesity in metabolic dysfunction-associated steatotic liver disease (MASLD), includi…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Testing a Multilevel, Culturally Appropriate Lifestyle Intervention For Hispanic Patients With Metabolic Dysfunction-associated Steatotic Liver Disease [NA]
The trial update indicates enrollment by invitation for a multilevel, culturally appropriate lifestyle intervention for Hispanic patients wi…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: The Establishment of Hong Kong Diabetes Steatotic Liver Disease Register
This clinical trial registry update announces the establishment of a Hong Kong register for metabolic dysfunction-associated steatotic liver…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Spleen Stiffness Measurement for the Detection of Advanced Fibrosis
Clinical trial update for a recruiting study evaluating spleen stiffness measurement as a noninvasive approach to detect advanced fibrosis i…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Using Digital Twin Technology and Clinical Decision Support Systems to Improve the Early Detection, Personalised Treatment, and Long-term Monitoring of Patients Across the Full Spectrum of Metabolic-associated Fatty Liver Disease (MAFLD).
A clinical trial update describes a study using digital twin technology and clinical decision support to improve early detection, personaliz…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: EVOO and Metabolic Liver Health in MASLD [NA]
This update describes a clinical trial investigating the effect of extra virgin olive oil on metabolic liver health in MASLD patients who ar…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) [Phase 3]
A Phase 3 trial (ENLIGHTEN-Fibrosis) is ongoing to evaluate the efficacy and safety of Pegozafermin in participants with metabolic dysfuncti…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Evaluation of Miricorilant on Liver Fat in Patients With MASLD [Phase 1]
Phase 1 clinical trial evaluating Miricorilant on liver fat in patients with MASLD, including NASH and related conditions; currently recruit…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Stimulating Fat Tissue Storage With Niacin to Reduce Fat Accumulation in the Liver. [NA]
A clinical trial update from Université de Sherbrooke indicates recruitment for a study testing niacin to stimulate fat storage in adipose t…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Human Models of Selective Insulin Resistance: Pancreatic Clamp [Phase 1]
A Phase 1 clinical trial from Columbia University examining human models of selective insulin resistance. The study targets insulin resistan…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Duodenal ReCET for Suboptimally Controlled Type II Diabetes Mellitus and Steatotic Liver Disease [NA]
Clinical trial update for Duodenal ReCET evaluating its use in suboptimally controlled type 2 diabetes mellitus and metabolic dysfunction-as…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study of Electronic Clinical Decision Support Tools for Steatotic Liver Disease [NA]
A Vanderbilt University Medical Center study is evaluating electronic clinical decision support tools for metabolic dysfunction-associated s…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Glucagon Resistance in Patients With MASLD and T2DM [NA]
A recruiting clinical trial investigating glucagon resistance in patients with metabolic dysfunction-associated steatotic liver disease and …
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV [Phase 2]
A Phase 2 study to evaluate resmetirom in participants with MASLD and HIV; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Efficacy and Safety of Rifaximin-α in Treating MASLD [EARLY_Phase 1]
This clinical trial update notes an early-phase Phase 1 study evaluating the efficacy and safety of rifaximin-α for metabolic dysfunction-as…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Efficacy of 12-week Daytime Restricted Eating on Hepatic Steatosis of Obesity [NA]
This clinical trial update covers a study evaluating whether a 12-week daytime restricted eating regimen improves hepatic steatosis in adult…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Phase II Study Evaluating the Efficacy and Safety of DR10624 Injection in MASLD and MetALD Subjects [Phase 2]
A Phase II clinical trial evaluating the efficacy and safety of DR10624 Injection in metabolic dysfunction-associated steatotic liver diseas…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Ultrasound Liver Imaging for Classification of Metabolic Dysfunction-associated Steatotic Liver Disease
A clinical trial is evaluating ultrasound liver imaging to classify Metabolic Dysfunction-Associated Steatotic Liver Disease, and the study …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial [Phase 2]
Phase 2 mechanistic clinical trial evaluating a probiotic mixture for metabolic dysfunction-associated steatotic liver disease (MASLD) and n…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) [Phase 1]
This Clinical Trial Update reports on a Phase 1 single-ascending and repeated-dose study of LY3849891 in participants with MASLD and MASH, w…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Quantitative Ultrasound to Assess Steatotic Liver Disease in Children
A University of California, San Diego–led clinical trial is recruiting children to evaluate quantitative ultrasound for assessing metabolic …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA
Clinical trial studying the link between metabolic dysfunction-associated steatotic liver disease and mitochondria-associated membranes in p…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: ENDOCARE-SCREEN: Metabolic Liver Dysfunction Screening Study
ENDOCare-SCREEN is a screening study for metabolic liver dysfunction and related metabolic conditions, currently not recruiting.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Liver and Splenic Stiffness in Predicting Esophageal Varices Needing Treatment in MASLD Related Compensated Advanced Chronic Liver Disease.
A completed clinical trial from the Institute of Liver and Biliary Sciences examined whether liver and splenic stiffness can predict which M…