Metabolic Acidosis
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CLINICAL_TRIALS trial_result · 2021-04-26Clinical Trial Update: Evaluation of TRC101 in Subjects With Metabolic Acidosis Associated With Chronic Kidney Disease [Phase 3]
A Phase 3 trial evaluating TRC101 for metabolic acidosis in chronic kidney disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-22Clinical Trial Update: Metabolic Acidosis and Vascular Function in Patients With Chronic Kidney Disease [NA]
Completed clinical trial evaluating metabolic acidosis and vascular function in patients with chronic kidney disease; results posted in 2020…
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CLINICAL_TRIALS trial_result · 2020-07-14Clinical Trial Update: Alkalinization by Urologists & Nephrologists [Phase 4]
Phase 4 clinical trial update on alkalinization strategies involving urologists and nephrologists, completed.
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Evaluation of TRC101 in Subjects With Chronic Kidney Disease and Metabolic Acidosis [Phase 1, Phase 2]
A study updating on TRC101 in chronic kidney disease patients with metabolic acidosis in Phase 1/2; results posted.
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Alkali Therapy in Chronic Kidney Disease [Phase 2, Phase 3]
Phase 2/3 clinical trial update on alkali therapy for chronic kidney disease with metabolic acidosis; trial completed and results posted in …
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CLINICAL_TRIALS trial_result · 2019-07-31Clinical Trial Update: Bicarbonate in Patients With Out-of-hospital Cardiac Arrest [Phase 2]
Phase 2 trial updating bicarbonate use in out-of-hospital cardiac arrest has completed with results posted.
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CLINICAL_TRIALS research · 2017-11-28Clinical Trial Update: Use of Sodium Bicarbonate in Patients Treated With Topiramate [NA]
Clinical trial update examining the use of sodium bicarbonate in patients treated with topiramate, in the context of epilepsy and metabolic …
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FDA approval · 2017-09-19FDA Approved: SODIUM BICARBONATE — Original Application (International Medication Systems, Limited)
The FDA approved an original ANDA for a generic sodium bicarbonate product from International Medication Systems, Limited.
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation [NA]
This completed trial evaluated the effects of potassium bicarbonate on bone health and several physiological systems during immobilization. …
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Effects of Zeolite + Dolomite on Performance and Acidosis [NA]
A completed clinical trial evaluates the effects of zeolite combined with dolomite on performance and acidosis, with inflammation and oxidat…
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD) [Phase 3]
Phase 3 clinical trial update addressing correction of metabolic acidosis in end-stage renal disease; the current trial status is UNKNOWN.
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FDA approval · 2013-06-25FDA Approved: THAM — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for THAM (tromethamine) submitted by Hospira, Inc. The action updates the labeling/indication for TH…
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Incidence of Postoperative Ketosis and Metabolic Acidosis
ClinicalTrials.gov update notes the incidence of postoperative ketosis and metabolic acidosis in a Royal Marsden NHS Foundation Trust study;…
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CLINICAL_TRIALS research · 2012-08-02Clinical Trial Update: Changes in Acid Base Status During High Salt Intake [NA]
A completed clinical trial sponsored by the DLR German Aerospace Center evaluating how high salt intake influences acid-base status in indiv…
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CLINICAL_TRIALS trial_result · 2011-03-11Clinical Trial Update: Effect of Propofol and Sevoflurane on Lactate During Anesthesia for Pediatric Heart Catheterisation [NA]
A completed clinical trial evaluating the effect of propofol and sevoflurane on lactate levels during anesthesia for pediatric heart cathete…
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CLINICAL_TRIALS trial_result · 2010-10-22Clinical Trial Update: Metabolic Acidosis in Renal Transplant Patients [Phase 2]
Phase 2 trial update reporting completion of a study on metabolic acidosis in renal transplant patients.