Mesothelioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion [Phase 1]
Bristol-Myers Squibb is conducting a Phase 1 trial of MRTX1719 in MTAP-deleted solid tumors, including mesothelioma, non-small cell lung can…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for HiFiBiO's HFB200301 as a single agent and in combination with tislelizumab in adults with advanc…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Stereotactic Magnetic Resonance Guided Radiation Therapy [NA]
Clinical trial update on stereotactic MR-guided radiation therapy for multiple cancer types; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study [Phase 1, Phase 2]
This document reports the completion of a long-term safety study of tazemetostat in adults who previously received the drug in earlier trial…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) [Phase 2]
Pembrolizumab is being studied in a Phase 2 trial (MK-3475-158/KEYNOTE-158) for advanced solid tumors; the study is currently active but not…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
A Phase 1/2 study of TC-510 from TCR2 Therapeutics in mesothelin-expressing cancers is active but not recruiting, spanning multiple indicati…
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EMA approval · 2025-07-25EMA Authorised: Armisarte (previously Pemetrexed Actavis) (pemetrexed diacid monohydrate) — Actavis Group PTC ehf
Armisarte (pemetrexed diacid monohydrate) has been authorised in the EU for non-small cell lung cancer and mesothelioma; Actavis Group PTC e…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma [Phase 2]
This clinical trial update describes an ongoing Phase 2 study evaluating additional chemotherapy after surgery for malignant peritoneal meso…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
This clinical trial update reports long-term follow-up of participants treated with A2 Biotherapeutics' gene therapy products in solid tumor…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers [Phase 2]
Phase 2 study evaluating adoptive transfer of tumor-infiltrating lymphocytes (TIL) for advanced solid cancers, with multiple site-specific i…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Metastatic Mesothelioma
A pilot clinical trial investigating the role of gut flora in metastatic mesothelioma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors [Phase 1]
Phase 1 study of TBio-6517 alone or in combination with pembrolizumab in solid tumors was terminated.
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: CheckpOiNt Blockade For Inhibition of Relapsed Mesothelioma [Phase 3]
A Phase 3 trial evaluating checkpoint blockade therapy for relapsed mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: A Double Blind, Placebo Controlled, Randomized Phase II Study Evaluating Gemcitabine With or Without Ramucirumab , for II Line Treatment MPM [Phase 2]
A Phase II randomized trial evaluating gemcitabine with or without ramucirumab for second-line mesothelioma has completed.
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Dose Individualization of Pemetrexed - IMPROVE-I [Phase 4]
This report provides an update on the Phase 4 IMPROVE-I trial evaluating dose individualization of pemetrexed in non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 update describes the dose-escalation and expansion study of AROG4-01 in patients with advanced solid tumors, including mesothel…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types [Phase 1]
A Phase 1 study evaluating MT-8421 as monotherapy and in combination with nivolumab in selected advanced solid tumors has been terminated. T…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders [EARLY_Phase 1]
This early-phase trial aims to optimize parameters for hyperpolarized gas MRI to image a broad range of lung disorders, informing imaging pr…
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CLINICAL_TRIALS research · 2024-10-02Clinical Trial Update: Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1/2 evaluation of NGM707 as a monotherapy and in combination with pembrolizumab in advanc…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: New Preclinical and Clinical Approaches to Mesothelioma
This article reports on new preclinical and clinical approaches to mesothelioma, with a trial currently recruiting.
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: EXTRA-Meso (EXercise TheRApy in Mesothelioma) Feasibility [NA]
The EXTRA-Meso feasibility trial investigates exercise therapy for mesothelioma and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of PF-06952229 in adults with advanced solid tumors was terminated. Results were posted on 2024-06-26.
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: GPC3/Mesothelin-CAR-γδT Cells Against Cancers [Phase 1]
Phase 1 clinical trial evaluating GPC3/Mesothelin-CAR-γδT cells for pancreatic, lung, liver cancers and mesothelioma; currently recruiting.