Meningitis
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis
This entry updates a prospective clinical registry studying acute treatment and long-term outcomes of meningitis in children, covering bacte…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Risk Factors and Outcomes in Patients Treated in Neurocritical Care
This clinical trial update summarizes risk factors and outcomes for patients treated in neurocritical care, covering conditions such as suba…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in a 4 to 6 Year-old Population [Phase 3]
A Phase 3 trial of the ACYW135 group meningococcal polysaccharide conjugate vaccine (CRM197 vector) in 4- to 6-year-old children has complet…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)
This completed clinical trial analyzed cerebrospinal fluid in patients with cerebral toxoplasmosis to characterize CSF findings; the study a…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Acute Treatment and Long-term Assessment of Adult Infectious Meningitis
This clinical trial update outlines a planned study to evaluate acute treatment and long-term outcomes in adults with infectious meningitis,…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans
This ClinicalTrials.gov entry reports termination of a trial studying long-term sequelae after childhood meningitis and meningococcal purpur…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Causes of Secondary and Prolonged Fever During Treatment of Bacterial Meningitis and Viral Encephalitis
This clinical trial update describes a study investigating causes of secondary and prolonged fever during treatment of bacterial meningitis …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: QIAstat-Dx® Meningitis/Encephalitis Panel Performance Evaluation Study 001
Completed performance evaluation of the QIAstat-Dx Meningitis/Encephalitis Panel in detecting pathogens causing meningitis and encephalitis …
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Molecular Epidemiology of Enteroviruses Detected at the Virology Laboratory of Brest University Hospital During the Period 2018-2024: Retrospective Analysis of an Atypical Meningitis Epidemic in 2024 (BrEcho9Men)
This clinical trial update presents a retrospective molecular epidemiology analysis of enteroviruses detected at the Brest University Hospit…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections Globally
The BIGlobal Intervention Study, which aims to improve diagnosis and management of suspected brain infections globally, has completed.
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CLINICAL_TRIALS withdrawal · 2025-02-19Clinical Trial Update: Infections of the Central Nervous System
The clinical trial investigating infections of the central nervous system in adults with suspected meningitis and/or encephalitis has been w…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: ACTIVATE in Public Housing [NA]
A completed clinical trial (ACTIVATE) in public housing studying interventions related to pneumonia, influenza, varicella, meningitis, COVID…
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EMA approval · 2025-02-13EMA Authorised: Nimenrix (Neisseria meningitidis group A polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group C polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group W-135 polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group Y polysaccharide conjugated to tetanus toxoid) — Pfizer Europe MA EEIG
The EMA authorised Nimenrix, a quadrivalent meningococcal conjugate vaccine, for prevention of invasive meningococcal disease caused by sero…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Neonatal Comfort Seat Allowing Safe Lumbar Puncture and Minimizing Failure: a Randomized Controlled Trial [NA]
This entry describes a randomized controlled trial evaluating a Neonatal Comfort Seat to enable safe lumbar puncture and reduce procedural f…
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EMA withdrawal · 2025-02-05EMA Withdrawn: Penbraya (Neisseria meningitidis group A polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group C polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group W polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group Y polysaccharide conjugated to tetanus toxoid;Neisseria meningitidis group B fHBP protein subfamily A;Neisseria meningitidis group B fHBP protein subfamily B) — Pfizer Europe MA EEIG
EMA has withdrawn the marketing authorization for Penbraya, a meningococcal vaccine developed by Pfizer Europe MA EEIG. The withdrawal took …
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: TriVerity in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis
This is an update on the TriVerity diagnostic trial for emergency department patients with suspected infections and suspected sepsis. The st…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: QIAstat-Dx® Meningitis/Encephalitis Panel Performance Evaluation Study
A completed performance evaluation study assessed how well the QIAstat-Dx Meningitis/Encephalitis Panel detects pathogens causing meningitis…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Persistence of Immunogenicity Following Reduced PCV Dosing Schedules in South African Children
This trial update evaluates whether reduced pneumococcal conjugate vaccine dosing schedules maintain immunogenicity in South African childre…
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: Evaluation of the Levels of Calcitonin Gene-related Peptide and Substance P
A clinical trial is recruiting to measure levels of calcitonin gene-related peptide (CGRP) and Substance P in meningitis to explore potentia…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Immunogenicity and Safety Study of GSK's MenABCWY Vaccine in Healthy Adolescents and Adults Previously Primed With MenACWY Vaccine [Phase 3]
Phase 3 immunogenicity and safety results for GSK's MenABCWY meningococcal vaccine in healthy adolescents and adults previously primed with …
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Stem Cell Transplantation In-patient With Neurological Sequelae Due to Encephalitis or Meningitis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating inpatient stem cell transplantation for neurological sequelae after encephalitis or meningitis has bee…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Central Nervous System Infections in Denmark
A Danish clinical trial at Aalborg University Hospital is currently recruiting. It will study Central Nervous System infections, including m…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Meningococcal Serogroup ACYWX Conjugate Vaccine in Comparison With MenACWY-TT Conjugate Vaccine [Phase 3]
A Phase 3 trial comparing a meningococcal serogroup ACYWX conjugate vaccine with the MenACWY-TT conjugate vaccine; results were posted after…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: Immunogenicity and Safety of Meningococcal ACYW135 Polysaccharide Conjugate Vaccine in Volunteers Aged From 3 to 5 Months [Phase 3]
Phase 3 trial update assessing immunogenicity and safety of a meningococcal ACYW135 polysaccharide conjugate vaccine in infants aged 3 to 5 …
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FDA approval · 2023-10-31FDA Approved: AMPICILLIN — Original Application (Aurobindo Pharma Limited)
FDA approved an original application for Ampicillin from Aurobindo Pharma Limited, granting marketing authorization for a generic ampicillin…