Melasma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma [Phase 2]
A Phase 2 clinical trial comparing the efficacy and safety of hydroquinone 4% cream with versus without a fractional picosecond 1,064 nm las…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Efficacy and Safety of Picosecond, Neodymium-doped Yttrium Aluminum Garnet Laser Therapy Using 1,064 nm and 595 nm [NA]
Clinical trial update reports on the efficacy and safety of a picosecond Nd:YAG laser therapy for melasma (1,064 nm and 595 nm).
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin [NA]
A prospective multi-center study evaluating laser treatment for melasma and lentigines in Asian skin has completed.
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CLINICAL_TRIALS research · 2017-01-02Clinical Trial Update: 1064-nm Q-switched Nd:YAG Laser and Intradermal Tranexamic Acid for Melasma [NA]
A trial update on using a 1064-nm Q-switched Nd:YAG laser in combination with intradermal tranexamic acid for melasma; the current trial sta…
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Evaluation of an Herbal-Based De-Pigmenting System [Phase 4]
Phase 4 clinical trial evaluating an herbal-based de-pigmenting system for treating melasma and hyperpigmentation has completed.
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Combination Alexandrite Laser and Topical Therapy vs Topical Therapy Alone for Treatment of Melasma [NA]
This clinical trial compared the combination of Alexandrite laser and topical therapy versus topical therapy alone for the treatment of mela…
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: Comparative Study of Dual Yellow Laser Versus Stabilized Kilnman Preparation in the Treatment of Melasma [NA]
A completed clinical trial comparing Dual Yellow Laser therapy to Stabilized Kilnman Preparation for melasma; the update does not provide tr…
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FDA approval · 2015-01-20FDA Approved: TRI-LUMA — Supplemental Application (Galderma Laboratories, L.P.)
The FDA approved a supplemental application for TRI-LUMA (fluocinolone acetonide, hydroquinone, and tretinoin) from Galderma Laboratories, L…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma [Phase 4]
This ClinicalTrials.gov update reports on a Phase 4 study evaluating ultraviolet and visible light photoprotection as a treatment for melasm…
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CLINICAL_TRIALS research · 2014-12-02Clinical Trial Update: Clinical Trial of Hydroquinone Versus Miconazol in Melasma [Phase 4]
A Phase 4 clinical trial comparing hydroquinone versus miconazole for melasma. The current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Inflammation in Melasma: Study of Its Infiltrate and the Expression of Acute and Chronic Mediators
This update summarizes a completed clinical trial investigating inflammation in melasma, including skin infiltrate and the expression of acu…
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FDA label_change · 2014-11-10FDA Approved: TRI-LUMA — Supplemental Application (Galderma Laboratories, L.P.)
The FDA approved a supplemental application for Tri-Luma from Galderma Laboratories, approving changes to the product labeling.
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FDA label_change · 2014-03-31FDA Approved: TRI-LUMA — Supplemental Application (Galderma Laboratories, L.P.)
FDA approved a supplemental application for Tri-Luma from Galderma Laboratories, L.P., likely updating labeling for this combination product…
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CLINICAL_TRIALS trial_result · 2014-02-13Clinical Trial Update: Prevention of Melasma Relapse During Summertime [NA]
Clinical trial update on preventing relapse of melasma during summertime. The study status is COMPLETED.
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CLINICAL_TRIALS research · 2014-01-28Clinical Trial Update: Clinical, Histological and Biochemical Characterization of Hyperpigmented Lesion
This clinical trial update reports on the clinical, histological, and biochemical characterization of a hyperpigmented lesion, with conditio…
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CLINICAL_TRIALS trial_result · 2013-12-30Clinical Trial Update: Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women [Phase 4]
Phase 4 trial update on salicylic acid peels combined with 4% hydroquinone for moderate to severe melasma in Hispanic women completed with r…
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CLINICAL_TRIALS trial_result · 2013-11-14Clinical Trial Update: Treatment of Melasma With Jessner's Solution vs. Trichloroacetic Acid [Phase 4]
Phase 4 trial comparing Jessner's solution to Trichloroacetic acid for melasma has completed. The study was sponsored by Emory University.
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FDA approval · 2013-10-18FDA Approved: TRI-LUMA — Supplemental Application (Galderma Laboratories, L.P.)
FDA approved a supplemental application for TRI-LUMA (fluocinonide, hydroquinone, and tretinoin) from Galderma Laboratories, L.P.
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FDA approval · 2013-07-12FDA Approved: TRI-LUMA — Supplemental Application (Galderma Laboratories, L.P.)
FDA approved a supplemental application for TRI-LUMA, a combination of fluocinolone acetonide, hydroquinone, and tretinoin, submitted by Gal…
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FDA approval · 2013-01-16FDA Approved: TRI-LUMA — Supplemental Application (Galderma Laboratories, L.P.)
The FDA approved a supplemental application for Tri-Luma (fluocinolone acetonide, hydroquinone, and tretinoin) submitted by Galderma Laborat…
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CLINICAL_TRIALS trial_result · 2012-05-04Clinical Trial Update: Melanil in the Treatment of Melasma [Phase 3]
A Phase 3 clinical trial evaluating Melanil for the treatment of melasma has completed.
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CLINICAL_TRIALS trial_result · 2012-03-26Clinical Trial Update: Treatment of Melasma With Stabilized Kligman Preparation Associated or Not With Pulsed Dye Laser [Phase 4]
Phase 4 clinical trial evaluating stabilised Kligman Preparation with or without pulsed dye laser for melasma has terminated.
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: Oral Polypodium Leucotomos for Melasma [NA]
A clinical trial evaluating oral Polypodium leucotomos extract for melasma has completed.
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CLINICAL_TRIALS trial_result · 2011-03-30Clinical Trial Update: In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy
The clinical trial NCT00771355 investigating in vivo imaging of pigmentary disorders by reflectance confocal microscopy has been terminated.…
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CLINICAL_TRIALS trial_result · 2010-11-23Clinical Trial Update: Fractional Photothermolysis for Treating Melasma [NA]
A completed clinical trial evaluating fractional photothermolysis as a treatment for melasma, sponsored by Laserklinik Karlsruhe.