Melasma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Annurca Apple Peel Oleolite for the Treatment of Skin Hyperpigmentation [NA]
A completed clinical trial evaluated Annurca Apple Peel Oleolite for treating skin hyperpigmentation, including melasma and related photodam…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser [NA]
Clinical trial comparing trichloroacetic chemical peel with fractional laser for treating melasma and acne scars; enrollment by invitation.
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Effectiveness of Oral Melatonin vs Oral Tranexamic Acid in the Treatment and Recurrence of Melasma [Phase 4]
Phase 4 clinical trial comparing oral melatonin with oral tranexamic acid for melasma treatment and recurrence. The study is currently activ…
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CLINICAL_TRIALS trial_result · 2025-05-05Clinical Trial Update: Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study [Phase 2]
A Phase 2 randomized, double-blind, split-face trial evaluated the efficacy of eflornithine hydrochloride cream for treating melasma; the st…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Topical Metformin Versus Topical Ketotifen in Melasma Treatment [Phase 2]
A Phase 2 clinical trial comparing topical metformin versus topical ketotifen for Melasma with recruitment not yet started.
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Oral Metformin for Treating Melasma in Latin American Women [Phase 1, Phase 2]
A clinical trial update describes a Phase 1/2 study evaluating oral metformin for treating melasma in Latin American women, currently recrui…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma [NA]
A pilot study comparing salicylic acid peels versus glycolic acid peels for the treatment of melasma; the trial is active but not recruiting…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMA [NA]
A completed clinical trial comparing a tested topical formula with hydroquinone 4% for facial melasma evaluated for efficacy and tolerabilit…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Comparison of Effectiveness and Safety of Triple Combination Cream of Fucinolone Acetonide 0.01%, Hydroquinone 4%, Tretinoin 0.05% with Mometasone Furoate 0.1%, Hydroquinone 4%, Tretinoin 0.05% in the Treatment of Melasma [NA]
This trial compares the effectiveness and safety of two triple-combination topical regimens for melasma: fluocinolone acetonide 0.01%/hydroq…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis [NA]
The trial evaluates a Centella asiatica-infused facial mask for rosacea, acne, and melasma, with status not yet recruiting.
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Randomized Study Using SM-030 Gel for Adults With Melasma [Phase 2]
A Phase 2 randomized trial evaluating SM-030 Gel for adults with melasma is currently recruiting, sponsored by DermBiont, Inc.
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Treatment of Melasma With Yellow Light Compared to Tranexamic Acid [NA]
A clinical trial comparing yellow light therapy to tranexamic acid for melasma was terminated.
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CLINICAL_TRIALS withdrawal · 2024-09-04Clinical Trial Update: Spironolactone for the Treatment of Melasma [Phase 1]
A Phase 1 trial evaluating spironolactone for the treatment of melasma has been withdrawn.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis [NA]
A clinical trial is recruiting to assess image-based computer gradings for analyzing acne, rosacea, melasma, and seborrheic dermatitis, spon…
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid [NA]
This entry notes an ongoing clinical trial comparing fractional Erbium YAG laser treatment with intradermal and systemic tranexamic acid for…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy [NA]
Clinical trial evaluating products based on secretome from stem cell conditioned medium for melasma is currently recruiting.
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma [NA]
This clinical trial update describes a study evaluating the anti-pigmenting effect of a facial product regimen in people with melasma. The t…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: A Cryotherapy With Tranexamic Acid Versus Normal Saline in the Treatment of Melasma [NA]
A clinical trial comparing cryotherapy with tranexamic acid to normal saline for the treatment of melasma, currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma [NA]
A clinical trial is recruiting to evaluate the efficacy and safety of delivering tranexamic acid to treat melasma (chloasma) using ultra-pul…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma [NA]
Clinical trial status update indicates that Sylfirm X radiofrequency microneedling is currently recruiting for melasma treatment.
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Lutronic PicoPlus Exploratory Clinical Trial [NA]
Exploratory clinical trial update for Lutronic PicoPlus (tattoo, pigmentation, melasma) has terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma [Phase 3]
Phase 3 trial comparing 3% topical tranexamic acid to 4% topical hydroquinone for the treatment of melasma; current status unknown.
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CLINICAL_TRIALS trial_result · 2023-08-28Clinical Trial Update: Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma. [Phase 2]
Phase 2 trial comparing TAM Formula versus Kligman Formula for melasma is in an unknown status.
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CLINICAL_TRIALS trial_result · 2023-08-07Clinical Trial Update: Cysteamine Compared to Hydroquinone in Melasma [Phase 3]
A Phase 3 trial comparing cysteamine to hydroquinone in the treatment of melasma has completed.
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Tranexamic Acid With Microneedling in Melasma [Phase 2]
Phase 2 clinical trial investigating tranexamic acid with microneedling for melasma.