Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update for MC1R-targeted alpha-particle monotherapy, with a nivolumab combination, in adults with advance…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: IL-17 Blockade to Decrease irAEs (REPLAY) [Phase 1]
A Phase 1 clinical trial (REPLAY) is evaluating an IL-17 blockade approach to reduce immune-related adverse events in patients with metastat…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma [NA]
This clinical trial update compares imaging characteristics of the uEXPLORER PET/CT scanner with conventional PET/CT in patients with lung c…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma [Phase 2]
Phase 2 clinical trial evaluating metronomic cyclophosphamide with pembrolizumab for checkpoint inhibitor-refractory melanoma; study is curr…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma [Phase 1]
Phase 1 trial evaluating an intralesional influenza vaccine for treating stage I-IV cutaneous melanoma; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases [Phase 1]
This phase 1 study assessed pembrolizumab in combination with stereotactic radiosurgery for patients with brain metastases from melanoma or …
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma [Phase 2]
A Phase 2 trial comparing three-study medicines (encorafenib, binimetinib, pembrolizumab) to two-study medicines (ipilimumab and nivolumab) …
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma
This clinical trial update describes an NCI study to characterize individuals and families at high risk of melanoma, including clinical, lab…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: A Study To Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Untreated, Unresectable or Metastatic Melanoma Participants In India [Phase 4]
ClinicalTrials.gov update for a Phase 4 study evaluating the safety and tolerability of a fixed-dose combination of nivolumab and relatlimab…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase II Clinical Trial on Neo-adjuvant Pembrolizumab in Patients With pT3b-T4a/b cN0M0 Melanoma. [Phase 2]
Phase II study assessing neoadjuvant pembrolizumab in patients with pT3b-T4a/b cN0M0 melanoma; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) [Phase 2]
Phase 2 basket study evaluating entrectinib in solid tumors harboring NTRK1/2/3, ROS1, or ALK gene rearrangements; the study is listed as Ac…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating a triple combination of tocilizumab, ipilimumab, and nivolumab for advanced melanoma, non-small cel…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma
Mayo Clinic is conducting a study to collect blood and tissue samples from family members of patients with pancreatic diseases, pancreatic c…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Characterisation of T Lymphocytes, NK Cells and Macrophages in Melanoma Patients
A completed clinical trial characterizing T lymphocytes, NK cells, and macrophages in melanoma patients to understand immune cell profiles i…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer [Phase 2]
Phase 2 trial evaluating psilocybin-assisted existential therapy (PEARL) for patients with advanced cancers; the study is currently active b…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 With Lymphocyte-depleting Chemotherapy and TILs in the Treatment of Melanoma [Phase 1]
A Phase 1 clinical trial evaluating TILT-123, an oncolytic adenovirus encoding TNFα and IL-2, in combination with lymphocyte-depleting chemo…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway [Phase 1]
Phase 1 trial of DCC-3084 for MAPK-pathway driven advanced cancers has been terminated. The update notes the study status without presenting…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: PD-L1 Targeting Peptide Probe for PET Imaging of Solid Tumor
A clinical trial update describes a PD-L1–targeting peptide probe for PET imaging of solid tumors, with not-yet-recruiting status and condit…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma [NA]
A trial is investigating consolidative radiotherapy to block oligoprogression in metastatic melanoma and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Belvarafenib in Combination With Cobimetinib in Patients With Locally Advanced or Metastatic NRAS-Mutant Melanoma [Phase 2]
A Phase 2 trial is evaluating belvarafenib in combination with cobimetinib for NRAS-mutant locally advanced or metastatic melanoma and is cu…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder [Phase 2]
Phase 2 clinical trial evaluating psilocybin-assisted psychotherapy for adjustment disorder in cancer patients; recruitment is ongoing acros…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases [Phase 1]
This document reports a Phase 1 trial update for an oncolytic adenovirus therapy targeting melanoma with intracranial and extracranial metas…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
This ClinicalTrials.gov entry notes molecular testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program and indicates on…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: RWS of Tunlametinib in NRAS-Mutant Advanced Melanoma [Phase 4]
Clinical trial update showing Phase 4 study of tunlametinib in NRAS-mutant advanced melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Investigating Real-Time Immunotherapy Symptoms Study [NA]
University of Pittsburgh is sponsoring a clinical trial to study real-time immunotherapy symptom monitoring, currently not yet recruiting, f…