Melanoma
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma [Phase 2]
A Phase 2 neoadjuvant and adjuvant trial evaluating anti-PD1 therapy alone or in combinations for locoregionally advanced melanoma is curren…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial [NA]
The DUO Trial is studying whether combining high-intensity exercise with a high-fiber diet affects immunotherapy outcomes in melanoma patien…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma [Phase 2]
A Phase 2 pilot trial evaluating the efficacy and safety of metformin in melanoma has completed. The study focused on patients with metastat…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Zimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory Melanoma [Phase 2]
Phase 2 trial update of zimberelimab (AB122) with domvanalimab (AB154) in PD-1 relapsed/refractory melanoma; the study is currently active b…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Circulating Cell-free DNA in Metastatic Melanoma Patient: Mutational Analyses in Consecutive Measurement Before and After Chemotherapy [NA]
This completed clinical trial provides mutational analyses of circulating cell-free DNA in a metastatic melanoma patient before and after ch…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours [Phase 1, Phase 2]
Ipsen is conducting a Phase 1/2 trial of IPN01194 as a single-agent therapy for adults with advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating CD40L-augmented tumor-infiltrating lymphocytes for advanced melanoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: TNF-Inhibitor as Immune Checkpoint Inhibitor for Advanced MELanoma [Phase 1]
Phase 1 trial completed evaluating a tumor necrosis factor (TNF) inhibitor as an immune checkpoint therapy for advanced melanoma. Sponsor: I…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-mutant Advanced Melanoma. [Phase 1]
A Phase 1 clinical trial evaluating belvarafenib as a single agent and in combination with cobimetinib or cobimetinib plus nivolumab in NRAS…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Neoadjuvant Pucotenlimab Combined With Lenvatinib and Temozolomide in Resectable Stage IIB/III Acral Melanoma [Phase 2]
A Phase 2 neoadjuvant trial is evaluating pucotenlimab with lenvatinib and temozolomide for resectable acral melanoma (Stage IIB/III); the s…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue [NA]
A Memorial Sloan Kettering Cancer Center trial evaluating radiation therapy for solid tumors that have metastasized to soft tissue. The stud…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Evaluation of Skin Tests in Biotherapy Allergies [NA]
A University Hospital, Angers-sponsored trial evaluating skin tests in biotherapy allergies is NOT_YET_RECRUITING. The study lists Locally A…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma [Phase 3]
Phase 3 trial update showing completion of a study comparing ABP-206, Amgen's nivolumab biosimilar, with Opdivo (nivolumab) in patients with…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating Nanrilkefusp alfa alone and with pembrolizumab in adults with advanced or metastatic solid tumors; the study (NCT04…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Safety and Efficacy of OBX-115 in Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update indicates OBX-115 is being studied in advanced solid tumors in Phase 1 and Phase 2, with recruitment ongoing for ind…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors [Phase 1, Phase 2]
Georgiamune Inc. is conducting a Phase 1/2 safety and tolerability trial of GIM-531 in patients with advanced solid tumors, including stage …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanoma [Phase 2]
A Phase 2 clinical trial evaluating LND101 in fecal microbiota transplantation combined with immune checkpoint blockade for advanced melanom…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma [Phase 1]
A Phase 1 study from Dana-Farber Cancer Institute evaluating NeoVax plus CDX-301 with nivolumab or pembrolizumab in melanoma; the trial is c…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Screening for Brain Metastases [Phase 2]
This clinical trial update describes a Phase 2 study on screening for brain metastases in patients with advanced lung cancer or melanoma, wh…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis [Phase 2]
A Phase 2 clinical trial evaluating a combination of binimetinib, encorafenib, and pembrolizumab, with or without stereotactic radiosurgery,…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis [Phase 1, Phase 2]
This document outlines an ongoing Phase 1/2 clinical trial evaluating Hepzato Kit in combination with Opdualag for metastatic melanoma with …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma [Phase 2]
A Phase 2 clinical trial (NCT06466434) investigating a prebiotic food-enriched diet to enhance the microbiome and improve response to first-…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial [Phase 2]
A Phase 2 clinical trial update on the PET-Stop trial uses biomarkers to guide safe discontinuation of immunotherapy in patients with unrese…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV [Phase 1]
This is a Phase 1 clinical trial evaluating the combination of cabozantinib (XL184) and nivolumab in patients with various advanced cancers …
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: A Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With Cancer [Phase 1]
A Phase 1 study of PF-07921585 alone or with other anti-cancer medicines in multiple cancers has been terminated.