Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-02-17Clinical Trial Update: Clinical Trial to Evaluate the Efficacy of Vemurafenib in Combination With Cobimetinib (Continuous and Intermittent) in BRAFV600-mutation Positive Patients With Unresectable Locally Advanced or Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating vemurafenib with cobimetinib (continuous and intermittent) in BRAFV600-mutant unresectable/metastatic melanoma comp…
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: Phase II Trial of Stereotactic Body Radiotherapy Followed by Ipilimumab in Treating Patients With Stage IV Melanoma [Phase 2]
Phase II trial evaluating stereotactic body radiotherapy followed by ipilimumab in stage IV melanoma was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-12Clinical Trial Update: Trametinib With GSK2141795 in BRAF Wild-type Melanoma [Phase 2]
Phase 2 trial update evaluating trametinib with GSK2141795 in BRAF wild-type melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma [Phase 4]
Phase 4 neoadjuvant GM-CSF trial in cutaneous stage III/III melanoma has completed with results posted.
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CLINICAL_TRIALS research · 2020-02-05Clinical Trial Update: Skin Self-Examination Education During Mammography [NA]
A completed clinical trial assessing skin self-examination education during mammography for melanoma awareness.
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: A Study of NIVO Plus IPI and Guadecitabine or NIVO Plus IPI in Melanoma and NSCLC Resistant to Anti-PD1/PDL1 [Phase 2]
Phase 2 trial evaluating nivolumab plus ipilimumab with guadecitabine versus nivolumab plus ipilimumab in melanoma and non-small cell lung c…
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: Toripalimab in the Neoadjuvant Treatment of BRAF V600 Wild Type Melanoma [Phase 2]
Phase 2 trial update for toripalimab in neoadjuvant treatment of BRAF V600 wild-type melanoma (Stage IIIB-IV) is reported as status UNKNOWN.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Peginterferon and TIL Therapy for Metastatic Melanoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating peginterferon in combination with tumor-infiltrating lymphocyte (TIL) therapy for metastatic melanoma ha…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer [Phase 1, Phase 2]
Phase 1/2 trial update for an experimental in-situ cancer vaccine across multiple solid tumors, including breast, colorectal, prostate, mela…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Adoptive Transfer of Specific Melanoma Antigens CD8+ T Cells in Metastatic Melanoma Patients: a Phase I/II Study [Phase 1, Phase 2]
Phase I/II trial evaluating adoptive transfer of CD8+ T cells targeting melanoma antigens in metastatic melanoma patients has completed.
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating nab-paclitaxel with bevacizumab or ipilimumab as first-line therapy in patients with unresectable stage IV melanoma…
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic [Phase 2]
Phase 2 trial evaluating a molecularly targeted therapy in BRAF wild-type metastatic melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Pilot Study of the Safety/Efficacy of Combination Checkpoint Blockade + External Beam Radiotherapy in Stage IV Melanoma [Phase 1]
Phase 1 pilot study evaluating safety and efficacy of combining checkpoint blockade with external beam radiotherapy in stage IV melanoma; re…
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CLINICAL_TRIALS trial_result · 2019-12-27Clinical Trial Update: A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body [Phase 1]
Phase 1 trial of LY3009120 in advanced/metastatic cancer was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-12-20Clinical Trial Update: Phase II Study to Assess the Safety and Immunogenicity of recMAGE-A3+AS15 ASCI With or Without Poly IC:LC [Phase 2]
Phase II study of recMAGE-A3+AS15 ASCI with or without Poly IC:LC in melanoma was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain [Phase 2]
Phase 2 trial update of abemaciclib in participants with brain-metastatic breast cancer, non-small cell lung cancer, or melanoma; study comp…
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating MK-3475 (pembrolizumab) in combination with INCB024360 in various selected cancers; study completed with results …
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CLINICAL_TRIALS trial_result · 2019-12-13Clinical Trial Update: Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer [Phase 2]
Phase 2 trial evaluating a dendritic cell vaccine targeting defined mutated neoantigens in autologous cancer patients with melanoma or gastr…
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CLINICAL_TRIALS trial_result · 2019-12-13Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001) [Phase 1]
Phase 1 study of pembrolizumab (MK-3475) in participants with progressive locally advanced/metastatic carcinoma, melanoma, or non-small cell…
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial update for autologous CAR-T/TCR-T cell immunotherapy targeting multiple malignancies; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma [Phase 1]
Phase 1 biomarker study evaluating nivolumab with ipilimumab, and nivolumab in combination with ipilimumab, in advanced/metastatic melanoma;…
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CLINICAL_TRIALS trial_result · 2019-11-19Clinical Trial Update: Hu14.18-Interleukin-2 Fusion Protein in Treating Patients With Advanced Melanoma [Phase 2]
Phase 2 trial assessing Hu14.18-Interleukin-2 fusion protein in advanced melanoma has been completed.
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases [Phase 2]
Phase 2 trial evaluating metformin for preventing glucocorticoid-induced diabetes in patients with brain metastases, with melanoma context.
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CLINICAL_TRIALS trial_result · 2019-11-12Clinical Trial Update: RFT-5-dgA in Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial update for RFT-5-dgA in metastatic melanoma; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: Tumor-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy Following Cyclophosphamide And Fludarabine In Patients With Melanoma [Phase 2]
Phase 2 trial evaluating tumor-infiltrating lymphocytes with low-dose interleukin-2 after cyclophosphamide and fludarabine in metastatic mel…