Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Trial of PI-88 With Dacarbazine in Patients With Metastatic Melanoma [Phase 2]
Phase II trial of PI-88 in combination with dacarbazine for metastatic melanoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant Melanoma [Phase 2]
A Phase 2 clinical trial evaluating axitinib, an anti-angiogenesis agent, in patients with stage III malignant melanoma has completed with p…
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma [Phase 2]
Phase II study of MEK162 as a single agent in patients with BRAF or NRAS mutant metastatic melanoma has completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Stage IV Melanoma [Phase 2]
Phase 2 trial of antineoplaston therapy in patients with Stage IV melanoma has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: A Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic Melanoma [Phase 1, Phase 2]
Clinical trial update for RAF265 in locally advanced or metastatic melanoma across Phase 1 and Phase 2; study completed.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol® [Phase 2]
Phase 2 trial updating autologous therapeutic vaccination against solid cancers using intratumoral Hiltonol shows completed status.
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Continuous vs Intermittent Dabrafenib Plus Trametinib in BRAFV600 Mutant Stage 3 Unresectable or Metastatic Melanoma [Phase 2]
Phase 2 trial update comparing continuous vs intermittent dabrafenib plus trametinib in BRAFV600-mutant unresectable/metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2020-11-23Clinical Trial Update: Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT) [Phase 2]
Phase 2 trial exploring pembrolizumab effects on natural killer cell exhaustion in melanoma was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-11-19Clinical Trial Update: A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma [Phase 3]
A Phase 3 trial evaluated atezolizumab plus cobimetinib and vemurafenib versus placebo plus cobimetinib and vemurafenib in previously untrea…
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CLINICAL_TRIALS trial_result · 2020-11-13Clinical Trial Update: Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma [Phase 3]
Phase 3 trial comparing fotemustine and dacarbazine to dacarbazine with or without alpha interferon in advanced malignant melanoma has compl…
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit [Phase 3]
A Phase 3 trial evaluating masitinib in metastatic melanoma with a c-KIT juxtamembrane domain mutation was terminated.
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Vaccination Plus Ontak in Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial update for vaccination plus Ontak in metastatic melanoma has been terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-10-26Clinical Trial Update: Ticilimumab (CP-675,206) in Treating Patients With Stage IIIC or Stage IV Melanoma [Phase 2]
Phase 2 trial update for ticilimumab (CP-675,206) in stage IIIC or stage IV melanoma; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer [Phase 1, Phase 2]
Phase 1/2 trial update of uprosertib combined with dabrafenib and trametinib in patients with stage IIIC-IV melanoma (cutaneous/metastatic/u…
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma [Phase 2]
Phase 2 trial investigating the effects of vemurafenib on the immune system in advanced melanoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Safety and Efficacy of Recombinant Humanized Anti-PD-1 mAb for Patients With Locally Advanced or Metastatic Melanoma [Phase 2]
Phase 2 clinical trial update evaluating safety and efficacy of a recombinant humanized anti-PD-1 monoclonal antibody in locally advanced or…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: International Trial of the Efficacy and Safety of BCD-100 in Patients With Melanoma [Phase 2]
Phase 2 clinical trial update for BCD-100 in patients with melanoma.
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Survivorship Promotion In Reducing IGF-1 Trial [Phase 2]
Phase 2 trial evaluating survivorship promotion by reducing IGF-1 has completed, with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations [Phase 2]
Phase II open-label trial evaluating dabrafenib plus trametinib in unresectable stage III/IV BRAF-mutant melanoma; study completed with post…
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Doxycycline, Temozolomide and Ipilimumab in Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating doxycycline with temozolomide and ipilimumab in melanoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Safety and Efficacy of Sonocloud Device Combined With Nivolumab in Brain Metastases From Patients With Melanoma [Phase 1, Phase 2]
Clinical trial update on safety and efficacy of the Sonocloud device combined with nivolumab for brain metastases from melanoma, spanning Ph…
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FDA approval · 2020-08-13FDA Approved: TEMOZOLOMIDE — Supplemental Application (Accord Healthcare Inc.)
FDA approves Accord Healthcare Inc.'s supplemental application for temozolomide, supporting a generic version of the drug. The action corres…
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CLINICAL_TRIALS trial_result · 2020-08-10Clinical Trial Update: Study of MLN2480 in Participants With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion in Participants With Metastatic Melanoma [Phase 1]
Phase 1 study of MLN2480 in relapsed/refractory solid tumors with dose expansion in metastatic melanoma has completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating a vaccine therapy for stage IV or recurrent malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161) [Phase 2]
Phase 2 trial investigating immunologic determinants of response to pembrolizumab (MK-3475) in advanced melanoma; study terminated with post…