Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: Ipilimumab Administered to Stage IIIC Stage IV Melanoma After Reg. T Cell Depletion With Denileukin Diftitox [Phase 2]
Phase 2 trial evaluating ipilimumab after regulatory T cell depletion with denileukin diftitox in stage IIIC/IV melanoma was terminated; res…
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CLINICAL_TRIALS trial_result · 2021-10-22Clinical Trial Update: Efficacy and Safety Study of Niraparib in Melanoma With Genetic Homologous Recombination (HR) Mutation [Phase 2]
Phase 2 trial evaluating niraparib for metastatic melanoma with homologous recombination mutations; efficacy and safety data not specified i…
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CLINICAL_TRIALS trial_result · 2021-10-05Clinical Trial Update: An Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by Itself [Phase 2]
Phase 2 trial evaluating safety and effectiveness of nivolumab plus ipilimumab, followed by nivolumab alone, in melanoma with brain metastas…
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Phase I/II Study of PDR001 in Patients With Advanced Malignancies [Phase 1, Phase 2]
Phase I/II trial update for PDR001 in advanced malignancies completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: A Study Using Tumor-Reactive Autologous Tumor Infiltrating Lymphocytes (TIL) in Metastatic Melanomas [Phase 2]
Phase 2 trial of tumor-reactive autologous tumor-infiltrating lymphocytes (TIL) in metastatic melanoma has terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-09-20Clinical Trial Update: myDC/pDC in Stage III Melanoma Patients [Phase 1, Phase 2]
Phase 1/2 clinical trial update on myDC/pDC therapy in Stage III melanoma patients has completed.
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: CMP-001 in Combo With Nivolumab in Stage IIIB/C/D Melanoma Patients With Clinically Apparent Lymph Node Disease [Phase 2]
Phase 2 trial evaluating CMP-001 in combination with nivolumab for Stage IIIB/C/D melanoma with clinically apparent lymph node disease has c…
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CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: Efficacy Study of Pharmacokinetic(PK)/Pharmacodynamic(PD) Relationship of Monotherapy MORAb-004 in Metastatic Melanoma [Phase 2]
Phase 2 study assessing PK/PD relationship of MORAb-004 monotherapy in metastatic melanoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-08-18Clinical Trial Update: TITAN (Tumoural Injection of T-VEC and Isolated Limb Perfusion) [Phase 1, Phase 2]
A phase 1/2 trial update evaluating Tumoural Injection of T-VEC with isolated limb perfusion in melanoma and sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2021-08-17Clinical Trial Update: Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases [Phase 2]
Phase 2 trial investigating concurrent dabrafenib and trametinib with stereotactic radiotherapy for BRAF mutation-positive melanoma with bra…
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: A Phase Ib Trial to Evaluate the Safety and Efficacy of FMT and Nivolumab in Subjects With Metastatic or Inoperable Melanoma, MSI-H, dMMR or NSCLC [Phase 1, Phase 2]
Phase Ib/II trial evaluating fecal microbiota transplant in combination with nivolumab for metastatic or inoperable melanoma and NSCLC; stat…
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CLINICAL_TRIALS trial_result · 2021-08-13Clinical Trial Update: Tumor and Vaccine Site With a Toll Like Receptor (TLR) Agonist [Phase 2]
Phase 2 trial update for a tumor and vaccine site using a Toll-Like Receptor agonist in melanoma; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced Malignancies [Phase 1, Phase 2]
Phase Ib/II study evaluating MCS110 with PDR001 in advanced malignancies; completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: RADVAX™: A STRATIFIED PHASE I/II DOSE ESCALATION TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOLLOWED BY IPILIMUMAB IN METASTATIC MELANOMA [Phase 1, Phase 2]
A stratified Phase I/II trial (RADVAX) assessing hypofractionated radiotherapy followed by ipilimumab in metastatic melanoma has completed e…
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: A Pilot Study of Sequential ONCOS-102, an Engineered Oncolytic Adenovirus Expressing GMCSF, and Pembrolizumab in Patients With Advanced or Unresectable Melanoma Progressing After Programmed Cell Death Protein 1 (PD1) Blockade [Phase 1]
Phase 1 trial evaluating sequential ONCOS-102 plus pembrolizumab in advanced or unresectable melanoma progressing after PD-1 blockade.
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CLINICAL_TRIALS trial_result · 2021-08-04Clinical Trial Update: Study of Gene Modified Immune Cells in Patients With Advanced Melanoma [Phase 2]
Phase 2 clinical trial update for gene-modified immune cells in patients with metastatic melanoma; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-03Clinical Trial Update: A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Phase 1/2 trial investigating intratumoral SD-101 with pembrolizumab in metastatic melanoma or recurrent/metastatic head and neck squamous c…
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CLINICAL_TRIALS trial_result · 2021-08-03Clinical Trial Update: Camrelizumab Plus Amlotinib and Chemotherapy in the First-line Treatment of Melanoma [Phase 2]
A Phase 2 clinical trial update evaluating camrelizumab plus amlotinib and chemotherapy as first-line treatment for melanoma.
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CLINICAL_TRIALS trial_result · 2021-07-22Clinical Trial Update: An Investigational Immuno-therapy Study of Nivolumab Combined With Ipilimumab Compared to Nivolumab by Itself After Complete Surgical Removal of Stage IIIb/c/d or Stage IV Melanoma [Phase 3]
A Phase 3 trial evaluating nivolumab alone versus nivolumab plus ipilimumab after complete surgical removal of advanced melanoma; results ha…
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CLINICAL_TRIALS trial_result · 2021-07-12Clinical Trial Update: Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma [Phase 3]
This Phase 3 trial compares the combination of encorafenib (LGX818) plus binimetinib (MEK162) against vemurafenib monotherapy and encorafeni…
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: An Investigational Immuno-therapy Study of BMS-986205 Combined With Nivolumab, Compared to Nivolumab by Itself, in Patients With Advanced Melanoma [Phase 3]
Phase 3 trial comparing BMS-986205 combined with nivolumab vs nivolumab alone in advanced melanoma completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-07-01Clinical Trial Update: GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases [Phase 2]
Phase 2 trial evaluating the combination of Radiation and Yervoy (ipilimumab) in melanoma patients with brain metastases has completed with …
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CLINICAL_TRIALS research · 2021-07-01Clinical Trial Update: Risk Information and Skin-cancer Education for Undergraduate Prevention [NA]
A completed clinical trial update focusing on risk information and skin-cancer education for melanoma prevention among young adults.
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: RTA 408 Capsules in Patients With Melanoma - REVEAL [Phase 1, Phase 2]
Phase 1/Phase 2 trial update on RTA 408 capsules in melanoma patients, including unresectable stage III and metastatic stage IV disease. The…
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CLINICAL_TRIALS trial_result · 2021-06-21Clinical Trial Update: Hepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to Melanoma [Phase 3]
Phase 3 trial comparing hepatic arterial infusion with melphalan to standard therapy in unresectable liver metastases due to melanoma comple…