Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-08-28Clinical Trial Update: An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread [Phase 1, Phase 2]
Phase 1/2 trial investigating BMS-986205 with nivolumab alone and with nivolumab plus ipilimumab in advanced cancers, including melanoma and…
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CLINICAL_TRIALS trial_result · 2023-08-25Clinical Trial Update: Safety Study of a Helper Peptide Vaccine Plus Pembrolizumab [Phase 1, Phase 2]
A safety study of a helper peptide vaccine in combination with pembrolizumab in melanoma has completed phases 1 and 2 with posted results.
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CLINICAL_TRIALS trial_result · 2023-08-25Clinical Trial Update: CAcTUS - Circulating Tumour DNA Guided Switch [Phase 2]
Phase 2 clinical trial update for CAcTUS trial using circulating tumor DNA to guide treatment switching in melanoma.
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CLINICAL_TRIALS trial_result · 2023-08-18Clinical Trial Update: APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma [Phase 1]
Phase 1 trial of APX005M in combination with nivolumab and cabiralizumab in advanced melanoma, non-small cell lung cancer, and renal cell ca…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Perifosine in Treating Patients With Metastatic or Recurrent Malignant Melanoma [Phase 2]
Phase 2 clinical trial evaluating perifosine in patients with metastatic or recurrent malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Patient-led Surveillance Compared to Clinician-led Surveillance in People Treated for Localised Melanoma. [NA]
A completed clinical trial comparing patient-led versus clinician-led surveillance in localized melanoma; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Effectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C Melanoma [Phase 3]
Phase 3 trial evaluating nivolumab versus placebo to prevent recurrence of melanoma after complete resection of stage IIB/C melanoma; study …
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma [Phase 3]
A Phase 3 study of the anti-PD-1 antibody PDR001 in combination with dabrafenib and trametinib in advanced melanoma was terminated, with res…
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CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101) [Phase 1, Phase 2]
Clinical trial update for KVA12123 as a standalone and in combination with pembrolizumab in advanced solid tumors; current status is unknown…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma [Phase 3]
A Phase 3 trial evaluating combination chemotherapy with or without interleukin-2 and interferon alfa in metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin [Phase 3]
Phase 3 trial evaluating interferon alfa-2b with or without radiation therapy in patients with metastatic melanoma to regional lymph nodes.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating radiation therapy for newly diagnosed brain metastases from kidney cancer, melanoma, or sarcoma.
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: High-Dose Aldesleukin and Ipilimumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial evaluating high-dose ald( e)leukin and ipilimumab in unresectable stage III-IV melanoma; the study is terminated but results h…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
Open-label, multicenter Phase 1/2 trial evaluating PARP inhibitor E7449 as a single agent and in combination regimens for advanced solid tum…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Methylphenidate in Treating Patients With Melanoma [Phase 3]
A Phase 3 clinical trial evaluating methylphenidate for fatigue in patients with melanoma and unspecified adult solid tumors has been comple…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome [Phase 2]
Phase 2 trial evaluating tretinoin with or without fenretinide for patients with dysplastic nevus syndrome-related melanoma (skin cancer) ha…
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FDA approval · 2023-06-14FDA Approved: IMJUDO — Supplemental Application (AstraZeneca Pharmaceuticals LP)
The FDA approved a supplemental application for IMJUDO (tremelimumab) from AstraZeneca.
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: To Explore the Efficacy and Safety of SHR-1701 Combined With Temozolomide in the Treatment of Advanced Melanoma [Phase 2]
A Phase 2 clinical trial evaluating SHR-1701 in combination with temozolomide for advanced melanoma is in progress, with unknown status.
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity [Phase 1, Phase 2]
Clinical trial exploring risk factors of immune checkpoint inhibitor–mediated liver, GI, endocrine, and skin toxicity across early-phase tri…
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: Study of HL-085 in NRAS Mutant Advanced Melanoma [Phase 1, Phase 2]
Clinical trial update for HL-085 in NRAS-mutant advanced melanoma (Phase 1/2) completed.
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: HL-085+Vemurafenib to Treat Advanced Melanoma Patients With BRAF V600E/K Mutation [Phase 2]
Phase 2 clinical trial evaluating HL-085 in combination with vemurafenib for advanced melanoma with BRAF V600E/K mutation.
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: HL-085 in NRAS-mutated Advanced Melanoma [Phase 2]
Phase 2 clinical trial update for HL-085 in NRAS-mutated advanced melanoma has completed enrollment and is in Phase 2.
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis [Phase 2]
Phase 2 open-label trial evaluating standard-dose vs high-dose encorafenib + binimetinib in BRAFV600-mutant melanoma with brain metastases; …
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CLINICAL_TRIALS trial_result · 2023-05-26Clinical Trial Update: Safety and Efficacy Study of QLF31907 in Advanced Melanoma and Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating QLF31907 for safety and efficacy in advanced melanoma and urothelial carcinoma is ongoing with status cu…
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Exercise as a Supportive Measure for Patients Undergoing Checkpoint-inhibitor Treatment [Phase 2]
Phase 2 trial update investigating exercise as a supportive measure for patients receiving checkpoint inhibitors.