Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma. [NA]
Exploratory study evaluating whether adding high-fiber dried chicory root to standard care affects outcomes in patients with intermediate-to…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Tovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid Tumors [Phase 2]
Phase 2 monotherapy trial of tovorafenib (DAY101) in melanoma and other solid tumors was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating infusion of NY-ESO-1–specific TCR-engineered lymphocytes in patients with NY-ESO-1-expressing…
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CLINICAL_TRIALS other · 2025-10-02Clinical Trial Update: Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors [Phase 1, Phase 2]
Clinical trial update for a phase 1/2 autologous and allogeneic whole cell cancer vaccine in metastatic tumors, currently recruiting across …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Intrathecal Double Checkpoint Inhibition [Phase 1]
This Phase 1 clinical trial from the University of Zurich investigates intrathecal double checkpoint inhibition for leptomeningeal metastasi…
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CLINICAL_TRIALS withdrawal · 2025-10-02Clinical Trial Update: Modified Melanoma Vaccine for High Risk or Low Residual Disease Patients [Phase 2, Phase 3]
The phase 2/3 trial of a Modified Melanoma Vaccine for high-risk HLA-A2+ melanoma and metastatic melanoma has been withdrawn.
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CLINICAL_TRIALS safety_alert · 2025-10-01Clinical Trial Update: CARDiac Toxicity Following ImmunOtherapy Treatment for Melanoma
The clinical trial update reports cardiac toxicity concerns linked to immunotherapy for melanoma and indicates ongoing safety monitoring for…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Cryotherapy With in Situ Immunotherapy in Melanoma Metastasis [Phase 1, Phase 2]
Completed Phase 1/2 study evaluating cryotherapy with in situ immunotherapy for metastatic melanoma (skin).
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Encorafenib and biNimetinib Followed by CEmiplimab and FiAnLimab in Patients With BRAF Mutant melanOma and Symptomatic Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating initial therapy with encorafenib and binimetinib followed by cemiplimab and fianlimab in patients with B…
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EMA withdrawal · 2025-10-01EMA Application withdrawn: Nidlegy (bifikafusp alfa;onfekafusp alfa) — Philogen S.p.A.
The European Medicines Agency has withdrawn the application for Nidlegy (bifikafusp alfa; onfekafusp alfa) indicated for melanoma, submitted…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Young Melanoma Family Facebook Intervention or Healthy Lifestyle Facebook Intervention in Improving Skin Examination in Participants With Melanoma and Their Families [NA]
Clinical trial evaluating Facebook-based interventions to encourage skin self-examination in melanoma patients and their families; currently…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: 18FDG PET for Early Identification of Tumor Exhaust for Immunotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Bronchopulmonary Carcinoma or Melanoma [NA]
A completed clinical trial evaluating 18F-FDG PET imaging to identify tumor exhaustion early to guide immunotherapy in patients with locally…
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CLINICAL_TRIALS withdrawal · 2025-09-29Clinical Trial Update: Pembrolizumab/Lenvatinib With and Without Healthy Donor FMT (hdFMT) in Relapsed/ Refractory (R/R) Melanoma [Phase 2]
A phase 2 trial evaluating pembrolizumab with and without healthy donor FMT plus lenvatinib in relapsed/refractory melanoma has been withdra…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Taxoprexin Treatment for Advanced Skin Melanoma [Phase 2]
A Phase 2 trial update reports completion of testing Taxoprexin in patients with advanced/metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Phase 1b Trial to Evaluate Safety of MB097 in Combination With Pembrolizumab in Melanoma Patients [Phase 1]
Phase 1b trial evaluates safety of MB097 in combination with pembrolizumab for melanoma; study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: NG2 and DLL3 CAR-T Cells Targeting Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating NG2-targeted and DLL3-targeted CAR-T cells for melanoma and is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: AI-Driven Early Detection of Skin Cancer
A clinical trial update announcing recruitment for an AI-driven approach to the early detection of melanoma (skin cancer).
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma [Phase 3]
A Phase 3 trial is evaluating HBI-8000 plus nivolumab versus placebo plus nivolumab in advanced unresectable or metastatic melanoma, includi…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001) [Phase 3]
Phase 3 trial update on Intismeran Autogene (V940) in combination with pembrolizumab for high-risk melanoma (V940-001), with the study curre…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: A Single Arm Trial Evaluating the Efficacy and Safety of EVX-01 in Combination With Pembrolizumab in Adults With Unresectable or Metastatic Melanoma [Phase 2]
A Phase 2 single-arm study is evaluating EVX-01 in combination with pembrolizumab for adults with unresectable or metastatic melanoma; the t…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: LUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory Melanoma [Phase 2]
Phase 2 clinical trial update (LUMINOS-102) evaluating lerapolturev with or without immune checkpoint blockade in advanced PD-1 refractory m…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Zr89 + PET Companion Trial [EARLY_Phase 1]
An early-phase 1 trial evaluating Zirconium-89 as a PET imaging companion for melanoma has completed.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Storage and Research Use of Human Bio-specimens From Melanoma Patients and Clinical Testing for Assignment of Treatment
A recruiting trial investigating storage and research use of biospecimens from melanoma patients and clinical testing for assignment of trea…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: A Study to Assess LBL-007 in Combination With Toripalimab and Axitinib Tablets Subjects With Advanced Melanoma [Phase 1]
Phase 1 study evaluating LBL-007 in combination with toripalimab and axitinib in advanced melanoma has completed.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: PLUG-IN: Pembrolizumab Combined With Enfortumab Vedotin for Advanced Melanoma Patients [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with enfortumab vedotin for advanced melanoma is currently recruiting.