Melanoma
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS) [Phase 2]
Phase 2 clinical trial evaluating optimization of immunotherapy for advanced melanoma in the Brazilian public health system; the study is cu…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis [Phase 2]
Phase 2 clinical trial update on infliximab for immune checkpoint inhibitor–induced colitis; the study in melanoma patients is currently act…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors [NA]
A clinical trial update for proton pencil beam scanning GRID therapy aimed at bulky tumors, with ongoing activity but not recruiting, invest…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma [Phase 1]
Phase 1 trial of the modified virus VSV-IFNbetaTYRP1 in stage III-IV melanoma was terminated.
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Pilot Study of Biomarkers of Response to Immune Checkpoint Blockade in Metastatic Melanoma
This is a completed pilot clinical trial assessing biomarkers of response to immune checkpoint blockade in metastatic melanoma. The study ai…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy [Phase 1]
Phase 1 clinical trial evaluating a vaccine therapy in combination with pembrolizumab for adults with various solid tumors that have failed …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies
Expanded access program for Ulixertinib (BVD-523) in patients with advanced MAPK pathway-altered malignancies across multiple tumor types. T…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: IMmune checkPoint Inhibitor Related gonAdal toxiCiTy in Premenopausal Women and Men With Melanoma
Immune checkpoint inhibitor–related gonadal toxicity in premenopausal women and men with melanoma is described. The study is currently recru…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi
A clinical trial evaluating the effects of anti-PD1 adjuvant checkpoint blockade immunotherapy on atypical/dysplastic nevi in melanoma patie…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: The Use of Dendritic Cell/Tumor Hybridomas as a Novel Tumor Vaccine in Patients With Advance Melanoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating a dendritic cell/tumor hybridoma vaccine for metastatic melanoma.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study [NA]
This update reports completion of the INSPIRE-AYA clinical trial, an interactive survivorship program aimed at improving healthcare resource…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Elderly Cancer PatIents, Safety and qualiTy of Life Under immunOtheraPies [Phase 4]
Phase 4 clinical trial evaluating safety and quality of life in elderly patients with advanced/metastatic cancer undergoing immunotherapy ha…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma [Phase 3]
A Phase 3 trial evaluating MB11 against Opdivo (nivolumab) in previously untreated advanced melanoma, assessing pharmacokinetics, efficacy, …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Molecular Characterization of Advanced Stage Melanoma by Blood Sampling [NA]
This clinical trial update notes that the molecular characterization study of metastatic melanoma using blood sampling has completed.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization [Phase 1]
Phase 1 trial evaluating an RNA-lipid particle vaccine intended to sensitize tumors to anti-PD-1 therapy in patients with melanoma and soft …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors. [Phase 1]
A Phase 1 study evaluating DKY709 alone or in combination with PDR001 in patients with advanced solid tumors. The enrolled diseases include …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Neoadjuvant Pembrolizumab in Patients With Stage IIb/c Melanoma [Phase 2]
Phase 2 neoadjuvant trial of pembrolizumab in patients with stage IIb/c melanoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery [Phase 1]
A Phase 1 clinical trial update evaluating the combination of pembrolizumab and ibrutinib for unresectable stage III–IV melanoma, sponsored …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients
This entry describes an ongoing University of Wisconsin–Madison clinical trial evaluating whether early FDG PET/CT imaging and circulating t…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma [Phase 2]
A Phase 2 clinical trial update for Botensilimab (AGEN1181) in advanced melanoma shows the study is ongoing with the status listed as active…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract
This clinical trial update describes the collection of tissue and blood from patients with benign and malignant tumors of the soft tissue an…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: IN10018 Monotherapy and Combination Therapy for Metastatic Melanoma [Phase 1]
Phase 1 trial update for IN10018 in metastatic melanoma, evaluating both monotherapy and combination therapy. The study status is completed.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases [Phase 2]
Phase II trial evaluating nivolumab in combination with relatlimab for active melanoma brain metastases is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Intratumoral N17350 in Advanced Solid Tumors [Phase 1, Phase 2]
Update on the investigational intratumoral therapy N17350 being studied in advanced solid tumors in Phase 1 and Phase 2 trials, sponsored by…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors [Phase 2]
ClinicalTrials.gov update for QUILT-3.055, a Phase 2 study of combination immunotherapies in patients who previously received immune checkpo…