Records containing: Melanoma
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CLINICAL_TRIALS study record update · 2026-10-09A Phase 1, Open-Label, Multiple-Ascending Dose Study of the Safety and Tolerability of CTX-471 Administered Either as a Monotherapy or in Combination With Pembrolizumab in Patients With Inadequate Responses to PD-1/PD-L1 Checkpoint Inhibitors in Metastatic or Locally Advanced Malignancies
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CLINICAL_TRIALS study record update · 2026-09-03A PHASE 3, RANDOMIZED, DOUBLE-BLIND STUDY OF ENCORAFENIB AND BINIMETINIB PLUS PEMBROLIZUMAB VERSUS PLACEBO PLUS PEMBROLIZUMAB IN PARTICIPANTS WITH BRAF V600E/K MUTATION-POSITIVE METASTATIC OR UNRESECTABLE LOCALLY ADVANCED MELANOMA
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CLINICAL_TRIALS study record update · 2026-06-03A Phase 3, Randomized, Open-label, Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination Versus Intravenous Nivolumab + Relatlimab Fixed-dose Combination in Participants With Previously Untreated Metastatic or Unresectable Melanoma
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CLINICAL_TRIALS study record update · 2026-04-27Natural History Study of Early Life Exposures in Agriculture (ELEA)
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CLINICAL_TRIALS study record update · 2026-04-27The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)
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CLINICAL_TRIALS study record update · 2026-04-27Clinical Genetics Branch (CGB) Eligibility Screening Survey
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CLINICAL_TRIALS study record update · 2026-04-27A Prospective Study of Plasma Genotyping as a Noninvasive Biomarker for Genotype-directed Cancer Care
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CLINICAL_TRIALS study record update · 2026-04-27Sub-topic Four: Clinical Translation of Original Radioactive Drugs for Precision Diagnosis and Treatment of Gastrointestinal Tumors -Clinical Application Value of PET Imaging Targeting LRRC15 in Malignant Tumors
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CLINICAL_TRIALS study record update · 2026-04-27Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases
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CLINICAL_TRIALS study record update · 2026-04-27A Phase 1/1b Open-label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of KIN-2787 in Participants With BRAF and/or NRAS Mutation-positive Solid Tumors.
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CLINICAL_TRIALS study record update · 2026-04-27A Multicentre Randomised Open-label Phase III Study of Stereotactic Radiosurgery, in Addition to Standard Systemic Therapy for Patients With Metastatic Melanoma or Newly Diagnosed Metastatic NSCLC and Asymptomatic or Oligo-symptomatic Brain Metastases
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CLINICAL_TRIALS study record update · 2026-04-24A Phase II Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor-Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
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CLINICAL_TRIALS study record update · 2026-04-24Assessment of Drug-Drug Interactions Between Immune Checkpoint Inhibitors and Cytochrome P450 Substrates: Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study
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CLINICAL_TRIALS study record update · 2026-04-24Clinical Genetics Branch (CGB) Eligibility Screening Survey
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CLINICAL_TRIALS study record update · 2026-04-24An Open-Label, Multicenter, First-in-Human, Dose-Escalation and Expansion Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of DXC014 for Injection in Patients With Advanced Solid Tumors.
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CLINICAL_TRIALS study record update · 2026-04-24Evaluation for NCI Surgery Branch Clinical Research Protocols
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CLINICAL_TRIALS study record update · 2026-04-24Natural History Study of Early Life Exposures in Agriculture (ELEA)
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CLINICAL_TRIALS study record update · 2026-04-24A Phase II Clinical Trial of Anti-PD-1 mAb Therapy Alone or With Metabolic Modulators to Reverse Tumor Hypoxia and Immune Dysfunction in Solid Tumor Malignancies
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CLINICAL_TRIALS study record update · 2026-04-24The Value of Circulating Tumour DNA in Early Detection of Recurrence of Melanoma
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CLINICAL_TRIALS study record update · 2026-04-23A Randomized, Double-blind, Parallel-group Study to Compare Pharmacokinetics of GME751 (Proposed Pembrolizumab Biosimilar) and US-licensed and EU Authorized Keytruda® in Participants With Stage II and III Melanoma Requiring Adjuvant Treatment With Pembrolizumab
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CLINICAL_TRIALS study record update · 2026-04-23A PHASE 1, OPEN-LABEL, DOSE ESCALATION AND DOSE EXPANSION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND ANTI TUMOR ACTIVITY OF PF-07799933 (ARRY-440) AS A SINGLE AGENT AND IN COMBINATION THERAPY IN PARTICIPANTS 16 YEARS AND OLDER WITH ADVANCED SOLID TUMORS WITH BRAF ALTERATIONS
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CLINICAL_TRIALS study record update · 2026-04-23A PHASE 1A/B OPEN-LABEL MASTER STUDY OF PF-07799544 AS A SINGLE-AGENT AND IN COMBINATION WITH OTHER TARGETED AGENTS IN PARTICIPANTS WITH BRAF-MUTANT MELANOMA AND OTHER SOLID TUMORS
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CLINICAL_TRIALS study record update · 2026-04-23A Prospective Registry Study of a Primary Melanoma Gene-signature to Predict Sentinel Node (SN) Status and Determine Its Prognostic Value for More Accurate Staging of SN-negative Melanoma Patients.
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CLINICAL_TRIALS study record update · 2026-04-23Randomised Phase II Trial of Pembrolizumab and Radiotherapy in Melanoma
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CLINICAL_TRIALS study record update · 2026-04-23A Phase I/II Open-label Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD6750, a CD8 Guided IL-2 Agent Alone and in Combination With Other Anti-cancer Agents in Participants With Select Advanced or Metastatic Solid Tumors