Malignant Mesothelioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients with PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies [Phase 1]
Phase 1 trial update exploring pembrolizumab in combination with an autologous dendritic cell vaccine for PD-L1-negative malignant mesotheli…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: A Study of BGC515 Capsules in Subjects With Advanced Solid Tumors [Phase 1]
BridGene Biosciences' BGC515 capsules are in a Phase 1 trial for advanced solid tumors, including malignant mesothelioma and epithelioid hem…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Magnetic Resonance Imaging for Detection of Peritoneal Mesothelioma [NA]
Completed clinical trial evaluating magnetic resonance imaging for detection of malignant mesothelioma, including peritoneal mesothelioma.
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EMA withdrawal · 2024-07-30EMA Withdrawn: Pemetrexed Krka (pemetrexed disodium) — KRKA d.d.
EMA has withdrawn the product Pemetrexed Krka (pemetrexed disodium) from the market.
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for UCMYM802 Injection in mesothelin-positive advanced malignant solid tumors, listing several cance…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of PRT3645 conducted by Prelude Therapeutics in patients with several advanced solid tumors has completed, including breast …
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: Artificial Intelligence in Lung Cancer Screening
A completed clinical trial evaluating the use of artificial intelligence to improve lung cancer screening, including individuals with asbest…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of methoxyamine with cisplatin and pemetrexed disodium in patients with advanced solid tumors or …
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Nivolumab and Ipilimumab +/- UV1 Vaccination as Second Line Treatment in Patients With Malignant Mesothelioma [Phase 2]
Phase 2 trial update evaluating nivolumab and ipilimumab with or without UV1 vaccination as second-line therapy for malignant mesothelioma.
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesothelioma [Phase 1]
Phase 1 trial evaluating intratumor LMB-100 with ipilimumab in mesothelioma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated Mesothelioma [Phase 2]
Phase II trial of nivolumab plus ramucirumab in previously treated malignant mesothelioma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant Mesothelioma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating stereotactic body radiation therapy combined with Avelumab immunotherapy for malignant mesot…
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Ph 2/3 Study in Subjects With MPM to Assess ADI-PEG 20 With Pemetrexed and Cisplatin [Phase 2, Phase 3]
Phase 2/3 trial in mesothelioma evaluating ADI-PEG 20 with pemetrexed and cisplatin completed, with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma [Phase 2]
Phase II study overview for Mesothelioma Stratified Therapy (MiST), a multi-drug regimen trial in malignant mesothelioma.
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: Mesothelioma Avastin Plus Pemetrexed-cisplatin Study [Phase 2, Phase 3]
Clinical trial update for mesothelioma evaluating Avastin with pemetrexed-cisplatin in Phase 2 and Phase 3 completed.
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: Immunological Variables Associated to ICI Toxicity in Cancer Patients [Phase 2]
A Phase 2 clinical trial investigating immunological variables associated with immune checkpoint inhibitor toxicity in cancer patients.
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CLINICAL_TRIALS trial_result · 2022-10-04Clinical Trial Update: Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma [Phase 2]
Phase II trial of alisertib (MLN8237) in salvage malignant mesothelioma has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-08-23Clinical Trial Update: Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant Mesothelioma [Phase 1]
Phase 1 trial update of LMB-100, a mesothelin-targeted immunotoxin, in people with malignant mesothelioma.
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CLINICAL_TRIALS trial_result · 2021-12-02Clinical Trial Update: Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma [Phase 2]
Phase 2 trial of LMB-100 followed by pembrolizumab in malignant mesothelioma was terminated.
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: Vinorelbine in Mesothelioma [Phase 2]
Phase 2 clinical trial update for Vinorelbine in mesothelioma (completed).
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CLINICAL_TRIALS trial_result · 2021-04-09Clinical Trial Update: Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma [Phase 2]
Phase 2 trial of the EZH2 inhibitor tazemetostat in mesothelioma with BAP1 loss of function has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-11Clinical Trial Update: Olaparib in People With Malignant Mesothelioma [Phase 2]
Phase 2 trial update on olaparib in malignant mesothelioma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma [Phase 2]
Phase 2 trial update for antineoplaston therapy in malignant mesothelioma has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating radiofrequency ablation for patients with refractory or advanced lung cancer and related thoracic malignan…
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: HMPL-453 in Advanced Malignant Mesothelioma [Phase 2]
Phase 2 clinical trial update for HMPL-453 in advanced malignant mesothelioma.