Malignant Mesothelioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-17Clinical Trial Results: Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma [Phase 2]
Phase II multi-drug trial (MiST) in malignant mesothelioma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies [Phase 1]
Phase 1 trial evaluating CTX-471 as a monotherapy or in combination with pembrolizumab in patients who progressed after PD-1/PD-L1 inhibitor…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
NCI is recruiting for a tissue procurement and natural history study in patients with malignant mesothelioma, with thymoma listed among the …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors [Phase 1]
Phase 1 trial evaluating Fast TILs, a tumor-infiltrating lymphocyte therapy, for malignant pleural effusions arising from epithelial or meso…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Iparomlimab Plus Tovorilimab Combined With Bevacizumab and Chemotherapy as First-Line Treatment for Advanced Mesothelioma [Phase 2]
A Phase 2 clinical trial assesses iparomlimab plus tovorilimab with bevacizumab and chemotherapy as first-line therapy for advanced malignan…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: SW-682 in Advanced Solid Tumors [Phase 1]
Phase 1 trial update indicates SW-682 for advanced solid tumors, including malignant mesothelioma, is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery [Phase 1]
A Phase 1 trial update describes light dosimetry for photodynamic therapy using porfimer sodium in participants with malignant mesothelioma …
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors [Phase 1]
A Phase 1 trial evaluating donor natural killer cells with cyclophosphamide and etoposide in children and young adults with relapsed or refr…
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CLINICAL_TRIALS withdrawal · 2026-03-17Clinical Trial Update: Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma [Phase 2]
Phase 2 trial of APG-115 (Alrizomadlin) for BAP1 tumor predisposition syndrome with mesothelioma has been withdrawn.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Feasibility Study Evaluating Surgery for Mesothelioma After Radiation Therapy Using Extensive Pleural Resection [NA]
This feasibility trial investigates performing extensive pleural resection surgery after radiation therapy for mesothelioma; the study is li…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma [Phase 1, Phase 2]
A phase 1/2 study evaluating CAR.70-engineered IL-15-transduced cord blood-derived NK cells with lymphodepleting chemotherapy for advanced r…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers [Phase 1]
Nuvectis Pharma reports a Phase 1 clinical trial of NXP-900 in subjects with advanced cancers is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: An Open-label, Single-arm Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of KT032 Cell Injection in Patients With Mesothelin-positive Advanced Solid Tumors. [EARLY_Phase 1]
An early-phase, open-label, single-arm trial evaluating KT032 cell injections for safety, tolerability, pharmacokinetics, and preliminary ef…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors [Phase 1]
This update notes that ISM6331 is being studied in a Phase 1 trial with recruitment ongoing for participants with malignant mesothelioma and…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma [Phase 1]
Phase 1 trial update for SynKIR-110 in mesothelin-expressing ovarian cancer, cholangiocarcinoma, and mesothelioma, currently recruiting.
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EMA approval · 2026-01-16EMA Authorised: Alimta (pemetrexed) — Eli Lilly Nederland B.V.
EMA has authorised the marketing of Alimta (pemetrexed) for malignant mesothelioma and non-small cell lung cancer in the EU. The marketing a…
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EMA approval · 2026-01-15EMA Authorised: Pemetrexed Pfizer (previously Pemetrexed Hospira) (pemetrexed disodium;pemetrexed disodium hemipentahydrate) — Pfizer Europe MA EEIG
The European Medicines Agency authorised a pemetrexed disodium product marketed as Pemetrexed Pfizer (formerly Pemetrexed Hospira) for non-s…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease [Phase 1]
Phase 1 clinical trial evaluating rapid expansion of tumor-infiltrating lymphocytes (TILs) to treat metastatic pleural disease, including ma…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study of SGN-MesoC2 in Advanced Solid Tumors [Phase 1]
Seagen is conducting a Phase 1 study of SGN-MesoC2 in advanced solid tumors, including non-small cell lung cancer, ovarian cancer, pancreati…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: ......SMARTEST Trial...... [Phase 2]
The SMARTEST trial, a Phase 2 study sponsored by University Health Network in Toronto, has completed. It investigated a treatment for malign…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Study of TYK-01054 Capsules in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TYK-01054 capsules in patients with advanced solid tumors, including malignant mesothelioma; the study…
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EMA approval · 2025-11-21EMA Authorised: Yervoy (Ipilimumab) — Bristol-Myers Squibb Pharma EEIG
The European Medicines Agency authorised Yervoy (ipilimumab) for multiple cancer indications. It lists melanoma, renal cell carcinoma, non-s…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI [Phase 2]
Phase 2 trial evaluating magnesium to prevent HIOC-associated acute kidney injury is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 clinical trial assessing brentuximab vedotin for CD30-positive malignant mesothelioma that cannot be removed by surgery; currently r…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma [Phase 1, Phase 2]
Ongoing Phase 1/2 neoadjuvant trial evaluating durvalumab with tremelimumab, with and without chemotherapy, for malignant mesothelioma.