Malignant Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Study of Toripalimab or Combining With Temozolomide（iv） in the Treatment of Advanced/Metastatic Malignant Melanoma [Phase 2]
Phase 2 trial evaluating toripalimab alone or in combination with temozolomide for advanced/metastatic malignant melanoma.
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CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: Autologous TriMix-DC Therapeutic Vaccine in Combination With Ipilimumab in Patients With Previously Treated Unresectable Stage III or IV Melanoma [Phase 2]
Phase 2 trial evaluating autologous TriMix-DC vaccine plus ipilimumab in previously treated unresectable stage III/IV malignant melanoma; st…
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma [Phase 1]
Phase 1 dose-escalation study of combining BMS-936558 (MDX-1106) with ipilimumab in unresectable stage III/IV malignant melanoma completed.
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: Pembrolizumab With Carboplatin/Paclitaxel in Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial update involving pembrolizumab with carboplatin/paclitaxel in metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: Encorafenib + Binimetinib + Pembrolizumab in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating Encorafenib + Binimetinib + Pembrolizumab in unresectable or metastatic BRAF V600-mutant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: A Study of HX008 for the Treatment of Patients With Malignant Melanoma [Phase 2]
Phase 2 clinical trial update for HX008 in malignant melanoma.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant Melanoma [Phase 2]
A Phase 2 clinical trial evaluating axitinib, an anti-angiogenesis agent, in patients with stage III malignant melanoma has completed with p…
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: A Tissue Collection Study of Pembrolizumab (MK-3475) in Subjects With Resectable Advanced Melanoma [Phase 1]
Phase 1 tissue collection study of pembrolizumab (MK-3475) in subjects with resectable advanced melanoma has completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-11-13Clinical Trial Update: Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma [Phase 3]
Phase 3 trial comparing fotemustine and dacarbazine to dacarbazine with or without alpha interferon in advanced malignant melanoma has compl…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting) [Phase 1]
Phase 1 trial examining NY-ESO-1 protein vaccine with imiquimod as adjuvant in melanoma (adjuvant setting) has completed with results posted…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update for rovalpituzumab tesirine in DL3-expressing advanced solid tumors shows termination with results posted.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating a vaccine therapy for stage IV or recurrent malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2020-07-27Clinical Trial Update: IMCgp100-401 Rollover Study [Phase 2]
Phase 2 rollover study for IMCgp100 in malignant melanoma was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-07-08Clinical Trial Update: Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanoma [Phase 1]
Phase 1 trial update assessing tolerability of a bispecific targeted biologic (IMCgp100) in malignant melanoma has completed with results po…
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CLINICAL_TRIALS trial_result · 2020-06-12Clinical Trial Update: Cobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or After Treatment With Previous Immunotherapy and Atezolizumab Monotherapy in Participants With Previously Untreated Advanced Melanoma [Phase 1]
Phase 1 trial evaluating cobimetinib with atezolizumab in advanced melanoma, including patients whose disease progressed after prior immunot…
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CLINICAL_TRIALS trial_result · 2020-05-28Clinical Trial Update: Vaccine Treatment for Advanced Malignant Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial of a vaccine treatment for advanced malignant melanoma has been completed.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: Granulocyte Macrophage-Colony Stimulating Factor and Ipilimumab as Therapy in Melanoma [Phase 2]
Phase 2 trial evaluating granulocyte macrophage-colony stimulating factor (GM-CSF) and ipilimumab as therapy in metastatic malignant melanom…
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CLINICAL_TRIALS trial_result · 2020-03-12Clinical Trial Update: Study of Karenitecin (BNP1350) to Treat Malignant Melanoma [Phase 2]
Phase 2 trial update for Karenitecin (BNP1350) in malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis [Phase 2]
Phase 2 clinical trial evaluating the combination of vemurafenib and cobimetinib in patients with BRAF-mutated melanoma with brain metastase…
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma [Phase 4]
Open-label Phase 4 trial evaluating vemurafenib in patients with BRAF V600 mutation-positive metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2019-12-06Clinical Trial Update: Safety and Efficacy of Tag-7 Gene-modified Vaccine in Locally Advanced or Metastatic Malignant Melanoma or Kidney Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of a Tag-7 gene-modified vaccine in locally advanced or metastatic malignant mel…
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma. [Phase 3]
Phase 3 trial comparing CC-5013 to placebo in metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2019-06-17Clinical Trial Update: An Open-Label, Dose-Escalation Study of IMC-20D7S In Participants With Malignant Melanoma [Phase 1]
Phase 1 open-label dose-escalation study of IMC-20D7S in participants with malignant melanoma has completed; results were posted in 2019.
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FDA approval · 2019-05-17FDA Approved: PROLEUKIN — Supplemental Application (Iovance Biotherapeutics, Inc)
FDA approved a supplemental application for PROLEUKIN (aldesleukin) filed by Iovance Biotherapeutics. The approval updates the product label…
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CLINICAL_TRIALS trial_result · 2019-03-04Clinical Trial Update: Adjuvant PEG Intron in Ulcerated Melanoma [Phase 3]
Phase 3 trial update for adjuvant PEG Intron in ulcerated melanomas.