Malignant Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Study of IK-595 in RAS- or RAF-altered Advanced Tumors [Phase 1]
Phase 1 study of IK-595 in Ras- or Raf-altered advanced tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
An update on IMM-1-104's Phase 1/2a trial in advanced or metastatic solid tumors shows the study is currently active but not recruiting.
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CLINICAL_TRIALS other · 2025-08-06Clinical Trial Update: A Clinical Study of BT02 for the Treatment of Patients With Advanced Malignant Melanoma [Phase 1]
Phase 1 clinical trial update for BT02 in patients with advanced malignant melanoma; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors [Phase 1]
A Phase 1 trial of TRX518, an anti-GITR monoclonal antibody, in unresectable stage III/IV malignant melanoma or other solid tumors has compl…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma [Phase 1]
Phase 1 study evaluating MASE-T (ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells) for metastatic melanoma has been t…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Study of Taxoprexin Injection vs. Dacarbazine in Patients With Metastatic Malignant Melanoma [Phase 3]
A Phase 3 trial comparing Taxoprexin Injection to Dacarbazine for metastatic malignant melanoma has been terminated.
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CLINICAL_TRIALS withdrawal · 2025-05-31Clinical Trial Update: Study of Two Dose Levels of RTA 402 in Patients With Advanced Malignant Melanoma [Phase 2]
This entry reports the withdrawal of a Phase 2 study evaluating two dose levels of RTA 402 in patients with advanced malignant melanoma.
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study of IMM-6-415 in Ras/RAF-mutant solid tumors, including pancreatic ade…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Video-Tumorboard PLUS
A clinical trial update for Video-Tumorboard PLUS focusing on malignant melanoma using telemedicine indicates the study is currently recruit…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Immune PET and Proteomics for the Assessment of Response to Spatially Fractionated or Palliative Radiotherapy With or Without Immunotherapy [Phase 2]
Phase 2 clinical trial evaluating immune PET imaging and proteomics to assess response to spatially fractionated or palliative radiotherapy …
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CLINICAL_TRIALS other · 2025-05-14Clinical Trial Update: RAPA-201 Therapy of Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating RAPA-201 for solid tumors, including small cell and non-small cell lung cancer and several head and neck…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Evaluating the Efficacy and Safety of a Sequencing Schedule of Cobimetinib Plus Vemurafenib Followed by Immunotherapy With an Anti- PD-L1 Antibody in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma [Phase 2]
Phase 2 trial evaluating sequencing of cobimetinib plus vemurafenib followed by anti-PD-L1 immunotherapy in unresectable or metastatic BRAF …
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Immunotherapy With Nivolumab or Nivolumab Plus Ipilimumab vs. Double Placebo for Stage IV Melanoma w. NED [Phase 2]
A Phase 2 trial evaluating nivolumab alone or in combination with ipilimumab versus placebo in stage IV malignant melanoma has completed.
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating pembrolizumab in patients with advanced solid tumors, including squamous cell carcinoma of the head and neck, tripl…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Detection of Plasmatic Cell-free BRAF and NRAS Mutations : a New Tool for Monitoring Patients With Metastatic Malignant Melanoma Treated With Targeted Therapies or Immunotherapy ( MALT ) [NA]
This completed clinical trial investigates using plasmatic cell-free BRAF and NRAS mutations as a blood-based biomarker to monitor patients …
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary
Clinical trial update describing ongoing recruitment for a national cohort study of patients with malignant melanoma (resectable stage II–IV…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Diagnostic Precision of the AI Tool Dermalyzer to Identify Malignant Melanomas in Subjects Seeking Primary Care for Melanoma-suspected Cutaneous Lesions
The trial evaluated the diagnostic precision of the Dermalyzer AI tool for identifying malignant melanoma in primary care patients with mela…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Safety of UV1 Vaccination in Combination With Ipilimumab in Patients With Unresectable or Metastatic Malignant Melanoma [Phase 1, Phase 2]
A completed Phase 1/2 trial assessing the safety of combining UV1 vaccination with ipilimumab in patients with unresectable or metastatic ma…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: A Randomized Trial to Assess the Role of Imaging During Follow Up After Radical Surgery of High Risk Melanoma [NA]
A randomized trial to evaluate the role of imaging during follow-up after radical surgery in high-risk malignant melanoma.
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2 [Phase 1]
Phase 1 clinical trial evaluating the GD2-SADA:177Lu-DOTA complex in GD2-expressing solid tumors is currently recruiting, including small ce…
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CLINICAL_TRIALS withdrawal · 2024-09-23Clinical Trial Update: ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastases [Phase 2]
Phase 2 trial evaluating ECT with pembrolizumab for unresectable melanoma with superficial or superficial and visceral metastases has been w…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Neoadjuvant L19IL2/L19TNF- Pivotal Study [Phase 3]
Phase 3 pivotal neoadjuvant trial of L19IL2/L19TNF for malignant melanoma is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma [Phase 1, Phase 2]
A Phase I/II study evaluating LOAd703 in combination with atezolizumab for malignant melanoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: UV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic Melanoma [Phase 1]
This clinical trial update notes the completion of a Phase 1 study evaluating UV1 vaccine in combination with pembrolizumab for unresectable…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Identification of Olfactory Biomarkers of Skin Cancer From Skin Odor Samples: a Pilot Study [NA]
A pilot clinical trial aims to identify volatile biomarkers in skin odor that differentiate malignant melanoma, basal cell carcinoma, and sq…