Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Chronotherapy for Depressive Episodes [NA]
A clinical trial at St. Olavs Hospital is recruiting participants to study chronotherapy for depressive episodes.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Microdosing Psychedelics to Improve Mood [Phase 2]
A Phase 2 clinical trial investigating microdosing psychedelics to improve mood in adults with Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Olfactory Training and Emotional State [NA]
This clinical trial update reports the completion of a study evaluating whether olfactory training can improve emotional state in people wit…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Examination of Glutamate and mGluR5 in Psychiatric Disorders [NA]
The Yale University–sponsored trial examining glutamate signaling and mGluR5 involvement in major depressive disorder, post-traumatic stress…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Treatment, Emotion, and Neuromodulation of Depression (TREND) Study [NA]
The TREND study, investigating treatment, emotion, and neuromodulation for depression, has completed.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: A Study of Pregnant and Postpartum Women With and Without Mood Disorders
Completed clinical trial NCT03615794 sponsored by Johns Hopkins University studying mood disorders in pregnant and postpartum women.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: A Study on the Intervention Effect of Therapeutic Horticulture Based on the Healing System on Non-suicidal Self-injury in Adolescent Patients With Depression [NA]
A clinical trial evaluating the intervention effect of therapeutic horticulture based on a healing system on adolescents with depression who…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Ayahuasca and Esketamine for Major Depression [Phase 2]
Phase 2 trial evaluating ayahuasca and esketamine for severe major depressive disorder has completed.
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study [Phase 2]
Phase 2 trial evaluating selenium supplementation for improving depression in children and adolescents with major depressive disorder; the s…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression [NA]
Clinical trial update on transcutaneous vagal nerve stimulation aiming to modulate stress response in major depressive disorder; the study i…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Taking Action for College Students [NA]
Temple University is recruiting for a clinical trial studying major depressive disorder, bipolar disorder, and schizophrenia.
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Dance-movement Therapy in the Treatment of Adolescent Depression [NA]
This clinical trial evaluates dance-movement therapy for adolescent depression. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Comparative Study of Physiological and Cerebrovascular Reactivity in Depression, at the Three Phases of Emotion [NA]
This is a completed clinical trial update studying physiological and cerebrovascular reactivity in major depressive disorder across three em…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Transcranial Pulse Stimulation for Depression [NA]
The clinical trial evaluating transcranial pulse stimulation for major depressive disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862
A completed clinical trial evaluating cardiac markers in patients with both depression and coronary artery disease.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: tVNS, Motivation, and Insulin Sensitivity [NA]
A University of Bonn-led clinical trial is recruiting to study whether transcutaneous vagus nerve stimulation affects motivation and insulin…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Strengthening Families Living With HIV in Kenya [NA]
This is a completed clinical trial in Kenya evaluating a program to support families living with HIV, with a focus on ART adherence and asso…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Neural Mechanisms of Temporal Interference Stimulation on Improving Social Reward Function in Depression [NA]
This clinical trial update reports on a Shanghai Mental Health Center-sponsored study evaluating temporal interference stimulation to improv…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Open Label Optimization Study
An open-label optimization study for Major Depressive Disorder is listed as active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Study on Allopregnanolone and Depression in Women Across the Menopause Transition [NA]
Clinical trial evaluating allopregnanolone for depression in women across the menopause transition is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder [Phase 2]
Phase 2 clinical trial evaluating psilocybin for co-occurring major depressive disorder and borderline personality disorder has completed.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Behavioral Activation Teletherapy to Increase Physical Activity [NA]
A completed clinical trial evaluating behavioral activation teletherapy aimed at increasing physical activity in people with depression-rela…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: BDNF Gene Polymorphism and Antidepressants Treatment [Phase 4]
Phase 4 clinical trial update on whether BDNF gene polymorphism influences treatment with antidepressants in depression; the study has been …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda [NA]
A Vanderbilt University trial evaluates Mindfulness-Based Cognitive Therapy implemented in a Vietnamese Buddhist pagoda, focusing on depress…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Biomarkers of Antidepressant Resistance [NA]
A completed clinical trial investigating biomarkers associated with antidepressant resistance in depression.