Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study [NA]
Pilot clinical trial update for The Oh Happy Day Class - Digital Connections (OHDC-DC) sponsored by the University of Wisconsin–Madison, stu…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression [Phase 2]
Phase 2 clinical trial update from Stanford on ACE-D Aim 3 to enhance translation in depression. Recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Promoting Teenage Sleep for Improved Mental Health and School Performance [NA]
A recruiting clinical trial from Kristianstad University aims to promote teenage sleep to improve mental health and school performance, inve…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Social Media Intervention for Online Victimized Youth [NA]
This update describes an ongoing clinical trial at the University of Pittsburgh testing a social media–based intervention to help youth expe…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: ACT_for Alcohol Use Disorder and Depression [NA]
Clinical trial update for ACT for Alcohol Use Disorder and Depression (NCT06620276) indicating the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Novel Blood Test as a Biomarker in Mental Health
This clinical trial investigates a novel blood test biomarker for mental health conditions. The study (NCT06856161) is currently recruiting.
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FDA approval · 2026-03-04FDA Approved: DESIPRAMINE HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals NY LLC)
FDA approved a supplemental application for Desipramine hydrochloride by Amneal Pharmaceuticals NY LLC, authorizing the generic product (AND…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications [NA]
A clinical trial exploring brain network mechanisms underlying cognitive impairments across schizophrenia, bipolar disorder, and major depre…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care? [NA]
This is an update on a completed VA-sponsored trial comparing participatory system dynamics modeling with usual quality improvement to impro…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia [NA]
A clinical trial is currently recruiting to evaluate self neuro-modulation therapy for major depressive disorder with anhedonia.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Visual Frailty in Ageing
University of Edinburgh-sponsored clinical trial is currently recruiting to study visual frailty in aging, examining how frailty and age-rel…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness [NA]
This entry reports a completed clinical trial from the University of Washington evaluating technology-assisted implementation of a mobile he…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression [NA]
Clinical trial update from Stanford University evaluating stimulation targeting the dorsolateral prefrontal cortex and central executive net…
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CLINICAL_TRIALS withdrawal · 2026-03-04Clinical Trial Update: N2O for Acute Suicidality and Depression in the ED [Phase 2]
A Phase 2 clinical trial evaluating nitrous oxide for acute suicidality and major depressive disorder in the emergency department has been w…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Amygdala Neurofeedback for Depression - Large Scale Clinical Trial [NA]
A large-scale clinical trial is recruiting to evaluate amygdala neurofeedback as a treatment for Major Depressive Disorder.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Transdiagnostic Cognitive Biomarkers [NA]
University of Minnesota is updating a clinical trial on transdiagnostic cognitive biomarkers related to pain and depression, currently recru…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Neurostimulation Versus Therapy for Problems With Emotions [NA]
A Duke University-sponsored trial is comparing neurostimulation to therapy for problems with emotion regulation across mood and anxiety diso…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Group Intervention for Interpersonal Skills [NA]
This clinical trial update notes a Charité University-led study on a group interpersonal skills intervention for depressive and anxiety diso…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Efficacy and Safety of Accelerated Intermittent Theta-burst Stimulation (a-iTBS) in Adolescents With Depressive Disorder [NA]
A clinical trial is evaluating the efficacy and safety of accelerated intermittent theta-burst stimulation for adolescents with major depres…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Exercise-priming of CBT for Depression: the CBT+ Trial [NA]
This clinical study is investigating exercise-primed cognitive behavioral therapy for major depressive disorder (the CBT+ Trial). Recruitmen…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Treatment of Depression Post-SCI [NA]
A clinical trial investigating treatment of depression after spinal cord injury is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Intracranial Investigation of Neural Circuity Underlying Human Mood [NA]
A Baylor College of Medicine–sponsored intracranial study examining neural circuitry underlying mood is currently recruiting for depression …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Prospective Cohort Study of Response and Tolerability of Accelerated Intermittent Theta-burst Stimulation (1W-AiTBS)
Prospective cohort study evaluating response and tolerability of accelerated intermittent theta-burst stimulation (1W-AiTBS) for depression.…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Teen Brain Training (TBT) [Phase 1]
A Phase 1 trial of Teen Brain Training (TBT) in adolescents has completed, with results posted. The study examined suicidality (suicidal ide…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Mindfulness-based Psilocybin Therapy for PTSD [Phase 2]
Phase 2 clinical trial evaluating mindfulness-based psilocybin therapy for post-traumatic stress disorder and major depressive disorder; sta…