Lupus Nephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) [Phase 1, Phase 2]
Nkarta, Inc. is conducting a Phase 1/2 study of NKX019 for autoimmune diseases and is currently recruiting. The trial targets lupus nephriti…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases [Phase 1]
Exploratory Phase 1 clinical trial evaluating YTS109 Cell for relapsed/refractory autoimmune diseases, including systemic lupus erythematosu…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating CD19-BCMA CAR T cell therapy for refractory lupus nephritis, systemic sclerosis, and primary Sjögren's…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases [Phase 1]
Phase 1 trial update on YTS109 cell therapy for relapsed/refractory autoimmune diseases, currently recruiting across multiple indications.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Safety and Efficacy of ES-NK Cell Injection in the Treatment of Refractory Lupus Nephritis: an Early Clinical Study [EARLY_Phase 1]
Early Phase 1 clinical trial assessing the safety and potential efficacy of ES-NK cell injections for refractory lupus nephritis; the study …
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases [Phase 1]
Phase 1 clinical study of YTS109 cell therapy for refractory autoimmune diseases is currently recruiting. The trial will evaluate safety and…
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CLINICAL_TRIALS withdrawal · 2026-02-27Clinical Trial Update: A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis [Phase 2]
The Phase 2 Nipocalimab trial in adults with active lupus nephritis has been withdrawn.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis [Phase 3]
Phase 3 clinical trial update for Anifrolumab in adults with active proliferative lupus nephritis; the study is currently active but not rec…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CART19, autologous CD19-directed CAR T cells, for systemic lupus erythematosus and lupus nephritis.…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN) [Phase 2]
Phase 2 clinical trial update for rapcabtagene autoleucel in active, refractory systemic lupus erythematosus and lupus nephritis, currently …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101 [Phase 1]
Phase 1 study update for KYV-101 (CARTIMMUNE) evaluating autoimmune diseases including idiopathic inflammatory myopathies, diffuse cutaneous…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
A long-term follow-up study for participants previously treated with KYV-101; recruitment is ongoing across multiple autoimmune diseases.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis [Phase 3]
A phase 3 trial of voclosporin in adolescent and pediatric lupus nephritis has been terminated. The study was sponsored by Aurinia Pharmaceu…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Long-Term Voclosporin Treatment in Adolescent and Pediatric Subjects With Lupus Nephritis [Phase 3]
A Phase 3 trial evaluating long-term voclosporin for lupus nephritis in adolescents and pediatric patients was terminated.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Dapagliflozin in Active Lupus Nephritis [Phase 4]
A Phase 4 clinical trial is evaluating dapagliflozin for active lupus nephritis. The study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Multicenter Phase 2a Clinical Study to Evaluate SIM0278 in Subjects With Active Lupus Nephritis [Phase 2]
A multicenter Phase 2a study evaluating SIM0278 in active lupus nephritis is planned, with the trial status listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease [Phase 1, Phase 2]
A Clinical Trial Update announcing AbelZeta's C-CAR168 CAR T cell therapy is in Phase 1/Phase 2 studies for refractory lupus nephritis, with…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Comparing Efficacy and Safety of Telitacicept and Belimumab in Lupus Nephritis: A Retrospective Multicenter Cohort Study.
A retrospective multicenter cohort study comparing the efficacy and safety of telitacicept versus belimumab in lupus nephritis.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study to Assess Efficacy and Safety of HSK39297 Tablets in Patients With LN [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of HSK39297 tablets in lupus nephritis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis [Phase 1]
Phase 1 study evaluating UB-VV410 in adults with active refractory systemic lupus erythematosus or lupus nephritis; recruitment is currently…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Research Accelerated by You Lupus Registry
This clinical trial registry entry describes the Lupus Registry study sponsored by the Lupus Foundation of America, which is currently recru…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
CRC01 is being evaluated in a Phase 1/2 clinical trial for severe refractory systemic lupus erythematosus, including lupus nephritis, with t…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study to Assess Demographic, Pharmacologic, Biomarker, Clinical Features and Quality of Life (QoL) of Participants With Lupus Nephritis
A completed study by GlaxoSmithKline examining demographic, pharmacologic, biomarker, clinical features, and quality of life in participants…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) [Phase 2]
A Phase 2 study of ravulizumab in proliferative lupus nephritis and immunoglobulin A nephropathy has been terminated, with results posted in…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Detection of Anti-glomerular Basement Membrane Antibodies (Anti-GBM): a Promising Biomarker for Lupus Nephritis (LN)? [NA]
This update reports on evaluating anti-GBM antibodies as a biomarker for lupus nephritis in a completed trial. The trial status is completed…