Lung Adenocarcinoma
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Clinical Application of PET Imaging Targeting MSLN in Malignant Tumors
This entry describes an ongoing clinical trial evaluating an MSLN-targeted PET imaging tracer for malignant tumors, with recruitment underwa…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: 18F-FDG and 68Ga-FAPI PET/CT in Lung Adenocarcinoma [NA]
A completed clinical trial evaluated 18F-FDG and 68Ga-FAPI PET/CT imaging in lung adenocarcinoma. The sponsor is The First Affiliated Hospit…
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CLINICAL_TRIALS research · 2025-01-21Clinical Trial Update: Efficacy and Safety of Ensartinib in Neoadjuvant Therapy for Stage IIA - IIIB (Operable or Potentially Operable) ALK-Positive Lung Adenocarcinoma ：A Multicenter, Real-World Clinical Study [Phase 4]
Phase 4 multicenter real-world study evaluating the efficacy and safety of ensartinib as neoadjuvant therapy for stage IIA-IIIB ALK-positive…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma
This non-interventional real-world study assesses afatinib as first-line therapy and subsequent treatments in patients with advanced EGFR mu…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Lymph Node Pathologic Grading Strategy
The document reports a clinical trial by Fudan University investigating a lymph node pathologic grading strategy for lung adenocarcinoma, wi…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Plasma Exosomes Reveal the Efficacy of Targeted Therapy in Patients With EGFR Mutation in Lung Adenocarcinoma
This update notes a targeted therapy trial for patients with EGFR-mutant lung adenocarcinoma and that enrollment is by invitation.
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CLINICAL_TRIALS research · 2024-10-21Clinical Trial Update: WSI Based DL for Diagnosing the IASLC Grading System of Lung Adenocarcinoma
Clinical trial registry entry describing a study that uses whole slide image-based deep learning to diagnose the IASLC grading system in lun…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Retrospective Analysis of Clinical and CT Features to Predict Spread Through Air Space in Stage IA Lung Adenocarcinoma
Retrospective analysis examining clinical and CT features to predict spread through air space in Stage IA lung adenocarcinoma; the trial sta…
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CLINICAL_TRIALS other · 2024-10-10Clinical Trial Update: Segmentectomy for Solid-dominant Lung Cancer [Phase 3]
A Phase 3 clinical trial sponsored by Fudan University evaluating segmentectomy for solid-dominant lung cancer (lung adenocarcinoma) is curr…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: TP53 R248Q TCR-T Cell Therapy for Advanced Solid Tumor [EARLY_Phase 1]
Early-phase trial of TP53 R248Q-targeted TCR-T cell therapy for advanced solid tumors is not yet recruiting. The trial lists lung adenocarci…
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: Multi-omics Analysis to Characterize the Invasive Evolution of Pulmonary Subsolid Nodules
This update describes a multi-omics research study to characterize how pulmonary subsolid nodules evolve toward invasive adenocarcinoma.
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CLINICAL_TRIALS withdrawal · 2024-09-03Clinical Trial Update: SCION: SABR and Checkpoint Inhibition of NSCLC [Phase 2]
A Phase 2 trial (SCION) evaluating stereotactic ablative radiotherapy (SABR) with checkpoint inhibition for non-small cell lung cancer has b…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: Intraoperative Frozen Section Pathology to Diagnose the IASLC Grades for Lung Adenocarcinoma (ECTOP-1014)
Completed clinical trial evaluating intraoperative frozen section pathology to diagnose IASLC grades for lung adenocarcinoma (ECTOP-1014). T…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Advanced Lung Tumor Treated by Osimertinib Plus Anlotinib [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination of osimertinib and anlotinib for advanced non-small cell lung cancer with EGFR mutations…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Adjuvant Benmelstobart for Stage IB, Grade 3 Invasive Lung Adenocarcinoma [Phase 2]
Phase 2 trial evaluating adjuvant Benmelstobart for Stage IB, Grade 3 invasive lung adenocarcinoma (non-small cell lung cancer) is currently…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Cios Mobile 3D Spin for Robotic Bronchoscopy
Clinical trial update indicates the Mayo Clinic-sponsored study evaluating the Cios Mobile 3D Spin for robotic bronchoscopy has completed. T…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Differentiating the Invasiveness of Lung Adenocarcinoma by Dual Energy CT Parameter
This clinical trial aims to differentiate the invasiveness of lung adenocarcinoma using dual-energy CT parameters and is currently recruitin…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Segmentectomy for Ground Glass-dominant Invasive Lung Cancer (ECTOP-1012) [Phase 3]
A Phase 3 clinical trial (ECTOP-1012) evaluating segmentectomy for ground-glass-dominant invasive lung cancer is currently recruiting. The t…
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Pembrolizumab Plus Bevacizumab and Chemotherapy for ALK-rearranged NSCLC With Persistent 5'ALK [Phase 2]
Phase 2 clinical trial update for ALK-rearranged non-small cell lung cancer evaluating pembrolizumab plus bevacizumab and chemotherapy, with…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Tumor Microenvironment
Clinical trial update from University Hospital Heidelberg for lung adenocarcinoma, currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Efficacy and Safety of Tislelizumab Combined With Bevacizumab and Albumin Paclitaxel in Lung Adenocarcinoma [Phase 2]
Phase 2 trial evaluating tislelizumab with bevacizumab and albumin paclitaxel in advanced lung adenocarcinoma (Stage IV) has completed.
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CLINICAL_TRIALS trial_result · 2023-12-13Clinical Trial Update: Sublobar Resection for Adenocarcinoma in Situ/Minimally Invasive Adenocarcinoma Diagnosed by Intraoperative Frozen Section (ECTOP-1019) [Phase 3]
Phase 3 trial evaluating sublobar resection for adenocarcinoma in situ or minimally invasive adenocarcinoma diagnosed by intraoperative froz…
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CLINICAL_TRIALS trial_result · 2023-09-11Clinical Trial Update: Selective Lymph Node Dissection for cT1N0M0 Invasive NSCLC With CTR>0.5 Located in the Apical Segment (ECTOP-1018) [Phase 3]
Phase 3 clinical trial investigating selective lymph node dissection for early-stage invasive non-small cell lung cancer (cT1N0M0, CTR>0.5) …
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib [Phase 2]
A Phase 2 trial evaluated local ablative therapy for oligoprogressive, EGFR-mutated non-small cell lung cancer after treatment with osimerti…
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CLINICAL_TRIALS trial_result · 2023-07-20Clinical Trial Update: Pemetrexed and Platinum Use in the Neoadjuvant Setting for Resectable Stage II and IIIA Lung Adenocarcinoma (ECTOP-1002) [Phase 2]
Phase 2 trial evaluating pemetrexed and platinum as neoadjuvant therapy for resectable stage II-IVA lung adenocarcinoma has completed.