Liver Transplantation
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Sign up freeTop drugs studied for this disease
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FDA approval · 2012-12-10FDA Approved: TACROLIMUS — Supplemental Application (Sandoz Inc.)
FDA approved a supplemental application for tacrolimus from Sandoz Inc., updating labeling related to its use in preventing organ transplant…
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CLINICAL_TRIALS trial_result · 2012-11-19Clinical Trial Update: Steroid Free Immunosuppression in Liver Transplantation [Phase 4]
Phase 4 clinical trial update showing results of a steroid-free immunosuppression strategy in liver transplantation; the study is completed …
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Belatacept in Liver Transplant Recipients [Phase 2]
A Phase 2 trial of belatacept for immunosuppression in liver transplant recipients was terminated; results were posted in 2012.
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CLINICAL_TRIALS research · 2012-10-16Clinical Trial Update: Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement [NA]
Update on a clinical study investigating whether a bedside exercise device and activity reinforcement improve rehabilitation after heart tra…
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FDA approval · 2012-09-25FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approves a supplemental application for mycophenolate mofetil, the generic immunosuppressant, via Teva Pharmaceuticals USA, Inc. This ac…
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CLINICAL_TRIALS trial_result · 2012-09-14Clinical Trial Update: Albumin, Total and Free Fraction of Mycophenolic Acid, and Measurement of IMPDH Activity in Liver Transplants.
This completed liver transplant pharmacokinetic/pharmacodynamic study evaluated albumin binding of mycophenolic acid (total and free fractio…
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FDA approval · 2012-08-31FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Strides Pharma Science Limited)
The FDA approved a supplemental application for mycophenolate mofetil from Strides Pharma Science Limited. This approval supports continued …
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FDA approval · 2012-08-29FDA Approved: MYCOPHENOLATE MOFETIL — Supplemental Application (Strides Pharma Science Limited)
FDA approved a supplemental application to allow Strides Pharma Science Limited to market a generic version of mycophenolate mofetil.
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients
This completed clinical trial evaluated management of heparin-induced thrombocytopenia in liver transplant recipients.
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FDA approval · 2012-06-08FDA Approved: CELLCEPT — Supplemental Application (Genentech, Inc.)
The FDA approved a supplemental application for CELLCEPT (mycophenolate mofetil) submitted by Genentech, Inc.
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CLINICAL_TRIALS research · 2012-05-10Clinical Trial Update: Search for Transcriptional Biomarkers in a Conversion Protocol From Calcineurin Inhibitors to Mycophenolate Mofetil [NA]
This trial from Pontificia Universidad Catolica de Chile investigates transcriptional biomarkers in converting liver transplant recipients f…
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CLINICAL_TRIALS trial_result · 2012-04-05Clinical Trial Update: Immune System Suppression With Alemtuzumab and Tacrolimus in Liver Transplantation Patients [Phase 2]
A National Institute of Allergy and Infectious Diseases–sponsored Phase 2 trial evaluated immune suppression using alemtuzumab and tacrolimu…
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CLINICAL_TRIALS trial_result · 2012-02-07Clinical Trial Update: Randomized Phase II Study of Hepatitis C Immune Globulin Intravenous (Human), Civacir(TM), in Liver Transplantation [Phase 2]
A randomized Phase II trial evaluating Civacir (hepatitis C immune globulin intravenous) in liver transplant recipients was terminated; resu…
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FDA approval · 2012-02-06FDA Approved: PROGRAF — Supplemental Application (Astellas Pharma US, Inc.)
The FDA approved a supplemental application for PROGRAF (tacrolimus) from Astellas Pharma US, Inc., updating its label to cover transplant-r…
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: The Effects of Angiotensin II Receptor Blockade on Kidney Function and Scarring After Liver Transplant [Phase 4]
Phase 4 clinical trial evaluating whether angiotensin II receptor blockade affects kidney function and scarring after liver transplantation.…
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CLINICAL_TRIALS trial_result · 2011-09-22Clinical Trial Update: Efficacy and Safety of Basiliximab, Cyclosporine/Cyclosporine Microemulsion, and Steroids in Pediatric de Novo Liver Transplant Recipients Avoiding Intraoperative Steroids [Phase 3]
A Phase 3 trial in pediatric de novo liver transplant recipients evaluated basiliximab in combination with cyclosporine (including cyclospor…
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CLINICAL_TRIALS research · 2011-09-15Clinical Trial Update: An Observational Study to Assess the Effect of Calcineurin Inhibitors on Markers of Transplant Tolerance
An observational study examining how calcineurin inhibitors influence markers of transplant tolerance in liver transplant recipients.
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CLINICAL_TRIALS trial_result · 2011-07-06Clinical Trial Update: Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients [Phase 1]
Phase 1 trial update on withdrawing immunosuppression in pediatric liver transplant recipients has completed with results posted in 2011.
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CLINICAL_TRIALS research · 2011-04-20Clinical Trial Update: Assessment Of the Safety and Benefit of Prospective Immunosuppressive Drug Withdrawal in Liver Transplantation and Prediction of Operational Tolerance [Phase 2]
Phase 2 clinical trial evaluating the safety and potential benefits of prospective withdrawal of immunosuppressive therapy after liver trans…
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CLINICAL_TRIALS trial_result · 2011-04-07Clinical Trial Update: RESCUE Study - Everolimus in Liver Transplantation Recipients With Renal Insufficiency [Phase 3]
The RESCUE Phase 3 trial evaluated Everolimus in liver transplant recipients with renal insufficiency. The study is completed and results we…
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CLINICAL_TRIALS trial_result · 2011-03-03Clinical Trial Update: Peripheral Immunologic Response of Solid Organ Transplant Recipients to Depletion Versus Non-depletion Protocols
A completed clinical trial comparing depletion versus non-depletion immunosuppressive protocols in solid organ transplant recipients, examin…
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CLINICAL_TRIALS trial_result · 2011-03-03Clinical Trial Update: Measurement of Gastrointestinal (GI) and Health-related Quality of Life (HRQL) Outcomes in Liver Transplant Recipients [Phase 3]
Phase 3 clinical trial update evaluating gastrointestinal and health-related quality of life outcomes in liver transplant recipients; result…
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CLINICAL_TRIALS research · 2011-03-02Clinical Trial Update: Systemic Variables in the Saliva of Children Undergoing Liver Transplantation
A clinical trial investigating systemic variables in the saliva of children undergoing liver transplantation. The current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2011-01-11Clinical Trial Update: A Study to Evaluate the Efficiency of Intravenously Administered Cyclosporine in de Novo Liver Transplant Recipients [Phase 4]
Phase 4 trial evaluating intravenous cyclosporine for immunosuppression in de novo liver transplant recipients; results were completed and p…
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FDA approval · 2010-09-17FDA Approved: TACROLIMUS — Original Application (Mylan Pharmaceuticals Inc.)
FDA approved the original application for tacrolimus from Mylan Pharmaceuticals, enabling generic access to this immunosuppressant used to p…