Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2013-04-10Clinical Trial Update: Quantification of Drugs and Their Degradation Products [NA]
This clinical trial update from University of Cologne describes a study focused on quantifying drugs and their degradation products. It note…
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CLINICAL_TRIALS research · 2013-02-28Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Failure [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating transplantation of umbilical cord mesenchymal stem cells in combination with plasma exchange for liver…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Use of N-Acetylcysteine During Liver Procurement [Phase 2]
This ClinicalTrials.gov entry reports the completion of a Phase 2 study evaluating the use of N-acetylcysteine during liver procurement.
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FDA approval · 2013-01-15FDA Approved: ACETADOTE — Supplemental Application (Cumberland Pharmaceuticals Inc.)
FDA approved a supplemental application for Acetadote (acetylcysteine) from Cumberland Pharmaceuticals.
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CLINICAL_TRIALS research · 2012-10-24Clinical Trial Update: The Perioperative Value of Platelet Counts in Predicting Outcome After Liver Transplantation
This clinical trial investigates whether perioperative platelet counts can predict complications or death after liver transplantation.
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CLINICAL_TRIALS research · 2012-10-18Clinical Trial Update: Lactate Clearance According to the Presence of Hepatic Dysfunction
Clinical trial evaluating lactate clearance in sepsis patients with hepatic dysfunction, sponsored by Samsung Medical Center; current status…
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure [Phase 2]
Phase 2 evaluation of the ELAD System for acute liver failure has been completed. The update notes sponsor Vital Therapies, Inc. and the cur…
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CLINICAL_TRIALS trial_result · 2012-07-18Clinical Trial Update: Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study [Phase 2]
Phase 2 multicentre randomized trial evaluating everolimus for immunosuppression in de novo liver transplantation.
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CLINICAL_TRIALS research · 2011-09-16Clinical Trial Update: Breath Test for Patients With Acute Liver Disease for Early Detection of the Need for Transplant or Recovery
This clinical trial update notes a breath test being explored for patients with acute liver failure. The test aims to help determine the nee…
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CLINICAL_TRIALS trial_result · 2011-07-27Clinical Trial Update: The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure [NA]
This completed clinical trial evaluated whether Prometheus liver support dialysis affects cerebral metabolism in patients with acute liver f…
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CLINICAL_TRIALS trial_result · 2011-06-03Clinical Trial Update: A Study Evaluating the Efficacy of Glucocorticoids in Patients With Pre-ACLF-HBV [NA]
This document provides an update on a clinical trial evaluating glucocorticoids in patients with pre-ACLF due to hepatitis B. The current st…
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CLINICAL_TRIALS research · 2011-04-26Clinical Trial Update: Granulocyte Colony Stimulating Factor (G-CSF) in Acute Liver Failure and Alcoholic Hepatitis [NA]
ClinicalTrials.gov entry evaluating granulocyte colony-stimulating factor (filgrastim) in acute liver failure and alcoholic hepatitis. Curre…
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CLINICAL_TRIALS trial_result · 2011-04-11Clinical Trial Update: Allogeneic Bone Marrow Mesenchymal Stem Cells Transplantation in Patients With Liver Failure Caused by Hepatitis B Virus (HBV) [Phase 2]
Phase 2 clinical trial evaluating allogeneic bone marrow mesenchymal stem cell transplantation for liver failure caused by hepatitis B virus…
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CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: Efficacy & Safety of ALF-5755 in Patients With Nonacetaminophen Severe Acute Hepatitis & Early Stage Acute Liver Failure [Phase 2]
The document reports a Phase 2 clinical trial evaluating the efficacy and safety of ALF-5755 in patients with acute liver failure due to non…
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CLINICAL_TRIALS research · 2011-03-10Clinical Trial Update: Growth Factors and Hepatic Progenitor Cells in Acute Liver Failure
This clinical trial investigates how serum growth factors relate to hepatic progenitor cells in acute liver failure, sponsored by National T…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: Therapeutic Effects of Liver Failure Patients Caused by Chronic Hepatitis B After Autologous MSCs Transplantation
This update reports on the completed trial evaluating autologous mesenchymal stem cell transplantation for liver failure due to chronic hepa…
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CLINICAL_TRIALS research · 2010-10-20Clinical Trial Update: Liver Transplantation and Reticuloendothelial Clearance Capacity
This entry notes a completed clinical trial from the University of Edinburgh evaluating liver transplantation and its effect on reticuloendo…
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CLINICAL_TRIALS research · 2010-10-18Clinical Trial Update: Allogenic Bone Marrow Stem Cell Transplantation in Liver Failure [Phase 2]
A Phase 2 trial update evaluating allogeneic bone marrow stem cell transplantation for liver failure; no status or results are provided in t…
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CLINICAL_TRIALS trial_result · 2010-10-11Clinical Trial Update: Indocyangreen Elimination in Cirrhosis and Acute Liver Failure
This clinical trial update reports the completion of a study evaluating the elimination of indocyanine green in patients with liver cirrhosi…
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CLINICAL_TRIALS research · 2010-06-29Clinical Trial Update: Oxidative Stress and Microcirculation in Patient With Hepatic Failure Undergoing Liver Support Treatment
An update on a clinical trial investigating oxidative stress and microcirculation in a patient with hepatic failure undergoing liver support…
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CLINICAL_TRIALS trial_result · 2009-09-17Clinical Trial Update: Improvement of Liver Function in Liver Cirrhosis Patients After Autologous Mesenchymal Stem Cell Injection:a Phase I-II Clinical Trial [Phase 1, Phase 2]
Phase I/II clinical trial shows improvement in liver function in patients with liver cirrhosis after autologous mesenchymal stem cell inject…
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CLINICAL_TRIALS trial_result · 2009-09-15Clinical Trial Update: Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects [NA]
A completed clinical trial assessing the effect of branched-chain amino acids on muscle ammonia metabolism in patients with cirrhosis and in…
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CLINICAL_TRIALS trial_result · 2009-09-03Clinical Trial Update: Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure [Phase 4]
This Phase 4 study assesses the safety and tolerability of lipid emulsions used in parenteral and enteral nutrition in critically ill patien…
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CLINICAL_TRIALS research · 2009-08-06Clinical Trial Update: Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT
This clinical trial update examines citrate pharmacokinetics and regional citrate anticoagulation during CRRT in patients with acute kidney …
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CLINICAL_TRIALS trial_result · 2009-03-05Clinical Trial Update: Citrate Anticoagulation During MARS Treatment [Phase 2, Phase 3]
Clinical trial update on Phase 2/3 evaluation of citrate anticoagulation during MARS liver support treatment for liver failure.