Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure [NA]
This clinical trial update describes the use of plasma exchange and continuous hemodiafiltration for Wilson disease-related liver failure, w…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Terlipressin Administration in Patients Undergoing Major Liver Resection [Phase 2]
The Phase 2 trial evaluating terlipressin in patients undergoing major liver resection was terminated.
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen [Phase 3]
Phase 3 randomized trial of acetylcysteine for acute liver failure not caused by acetaminophen has completed (status: COMPLETED).
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Donor Simvastatin Treatment in Organ Transplantation [Phase 2, Phase 3]
Clinical trial update on donor simvastatin treatment in organ transplantation across Phase 2 and Phase 3, completed; conditions listed inclu…
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
A completed clinical trial evaluating central venous catheter colonisation in critically ill ICU patients, including individuals with sepsis…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Autoregulation Assessment During Liver Transplantation
This is an update of a completed clinical trial evaluating autoregulation during liver transplantation.
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Unknown Cause of Acute Liver Failure
A completed clinical trial investigating acute liver failure of unknown etiology; the update does not disclose trial results.
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Parenteral Lipid Emulsions and the Liver Function [Phase 4]
A Phase 4 trial evaluating the impact of parenteral lipid emulsions on liver function has completed.
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Intraoperative Dialysis in Liver Transplantation [NA]
The University of Alberta-sponsored intraoperative dialysis trial in liver transplantation (NCT01575015) has been terminated. The study targ…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant [Phase 2]
A Phase 2 trial evaluating gradual withdrawal of immunosuppressive therapy in liver transplant recipients; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood Pressure [NA]
A clinical trial evaluating the effects of postoperative blood pressure on renal perfusion, filtration, and oxygenation after liver transpla…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure [Phase 3]
Phase 3 clinical trial update for N-acetylcysteine in non-acetaminophen pediatric acute liver failure. The study has completed and results w…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Interstage Assessment of Remnant Liver Function in ALPPS
This completed clinical trial from Hospital Italiano de Buenos Aires evaluates interstage assessment of remnant liver function during the AL…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF [Phase 2]
Phase 2 pharmacokinetic and pharmacodynamic study of IDN-6556 in acute liver failure conditions was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel
This clinical trial update reports the completion of an extended drug utilization study evaluating adverse events among patients exposed to …
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF [NA]
This completed clinical trial compares hypertonic saline with mannitol for the management of raised intracranial pressure in patients with a…
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Liver Function Assessment - Feasibility and Dosing Study [NA]
A feasibility and dosing study for liver function assessment in hepatic failure was terminated.
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: A Multi-Center Group to Study Acute Liver Failure in Children
A multi-center study investigating acute liver failure and hepatic encephalopathy in children has completed.
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CLINICAL_TRIALS trial_result · 2015-11-03Clinical Trial Update: Human Fetal Liver Cell Transplantation in Chronic Liver Failure [Phase 1, Phase 2]
Clinical trial update reporting the completion of Phase 1 and Phase 2 studies of human fetal liver cell transplantation for chronic liver fa…
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CLINICAL_TRIALS trial_result · 2015-09-29Clinical Trial Update: Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). [NA]
A completed clinical trial evaluating whether the 13C methacetin breath test can predict prognosis in patients with acute liver failure and …
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CLINICAL_TRIALS trial_result · 2015-08-28Clinical Trial Update: Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients [Phase 2]
Phase 2 pharmacokinetic data for LCP-Tacro were evaluated in stable liver transplant patients. The study was sponsored by Veloxis Pharmaceut…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED) [Phase 1]
A completed Phase 1 study evaluating MK0431 in patients with hepatic insufficiency.
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CLINICAL_TRIALS trial_result · 2015-06-25Clinical Trial Update: Pharmacokinetics of LCP-Tacro™ Once Daily and Prograf® Twice A Day in Adult De Novo Liver Transplant Patients [Phase 2]
Clinical trial update comparing pharmacokinetics of LCP-Tacro given once daily versus Prograf given twice daily in adult de novo liver trans…
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure
This clinical trial update characterizes infections in patients with cirrhosis and/or acute-on-chronic liver failure, detailing the spectrum…
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CLINICAL_TRIALS trial_result · 2015-04-24Clinical Trial Update: SPME For Metabolomics And Concomitant Measurements Of Rocuronium Bromide Levels In Liver Transplantation
An update on a clinical trial evaluating solid-phase microextraction for metabolomics and simultaneous rocuronium bromide level measurements…