Liver Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation [NA]
This is a completed clinical trial update comparing hypothermic oxygenated perfusion to cold storage before liver transplantation. It involv…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Patients Undergoing Liver Transplantation Surgery
A completed clinical trial evaluating non-invasive measurement of SjvO2 using near-infrared spectroscopy in patients undergoing liver transp…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function [Phase 1]
Phase 1 study evaluating soticlestat in adults with hepatic impairment versus healthy volunteers; completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: BRIDGE Device for Post-operative Pain Control [NA]
A terminated clinical trial (BRIDGE Device) focusing on post-operative pain control in liver disease/failure contexts; results posted in 202…
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CLINICAL_TRIALS trial_result · 2022-07-29Clinical Trial Update: Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU [Phase 4]
A Phase 4 pharmacokinetic study evaluating continuous infusion of remazolam in mechanically ventilated ICU patients.
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CLINICAL_TRIALS trial_result · 2022-07-05Clinical Trial Update: Intravenous Ketamine Infusion on Postoperative Analgesia of Living Liver Donors [Phase 4]
A Phase 4 clinical trial update evaluating the effect of intravenous ketamine infusion on postoperative analgesia in living liver donor surg…
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: Mesenchymal Stem Cells After Renal or Liver Transplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating mesenchymal stem cells as an adjunct therapy after renal or liver transplantation completed.
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning [Phase 2]
Phase 2 trial of intravenous silibinin-legalon for hepatic failure due to amatoxin/Amita mushroom poisoning was terminated with posted resul…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia [Phase 4]
Phase 4 trial investigating avatrombopag for thrombocytopenia in patients with liver failure and related conditions, status currently unknow…
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation [Phase 2]
A Phase 2 randomized controlled trial evaluating Thymoglobulin after liver transplantation has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation [Phase 3]
Phase 3 trial assessing dual hypothermic oxygenated perfusion of DCD liver grafts to prevent biliary complications after transplantation has…
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF [Phase 2, Phase 3]
Phase 2/3 trial evaluating 13C-Methacetin Breath Test to predict outcomes in acute liver failure; completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-28Clinical Trial Update: Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of LifeLiver in acute liver failure and acute-on-chronic liver failure.
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CLINICAL_TRIALS trial_result · 2020-04-17Clinical Trial Update: Lipid Emulsions and Liver Function - Results After 5 Years. [Phase 4]
Phase 4 trial update on lipid emulsions and liver function with results after five years.
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CLINICAL_TRIALS trial_result · 2020-01-23Clinical Trial Update: Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants [Phase 4]
Phase 4 trial comparing FK506 (advagraf) drug levels between First Nations and Caucasian liver transplant patients.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure Study
A completed clinical trial on acute-on-chronic liver failure in China has posted results.
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy [Phase 3]
Phase 3 clinical trial assessing terlipressin for recovery of liver function after hepatectomy, with listed conditions including terlipressi…
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study [NA]
A completed feasibility and safety study evaluating remote ischemic conditioning in recipients of brain death donor livers; results posted i…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy [Phase 1, Phase 2]
Clinical trial update on pneumatic reversible portal vein diameter modulation after major hepatectomy, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure [Phase 4]
Phase 4 pharmacokinetic study assessing a single dose of caspofungin in patients with liver failure.
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant [EARLY_Phase 1]
An early-phase 1 trial evaluated the safety and preliminary efficacy of ProQuad in children 6-24 months being evaluated for solid organ tran…
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test [Phase 3]
Phase 3 clinical trial update for the LiMAx-test to identify low-risk patients after partial liver resection; study completed.
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant [NA]
A completed clinical trial evaluating whether vasopressin protects the kidneys in patients undergoing liver transplantation; results posted …
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CLINICAL_TRIALS trial_result · 2018-09-20Clinical Trial Update: Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury [Phase 2]
Phase 2 safety study of ornithine phenylacetate for acute liver failure/severe acute liver injury has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF) [Phase 2]
Phase 2 trial evaluating the ELAD System for acute liver failure was terminated; results were posted in 2018.