Liver Failure
📧 Sign up to get email alerts when something new happens for Liver Failure.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment [Phase 1]
Phase 1 trial update evaluating pharmacokinetics and safety of MDR-001 in mild and moderate hepatic impairment; status is not yet recruiting…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size Syndrome [Phase 1, Phase 2]
This clinical trial update describes safety and tolerability testing of a novel bioartificial liver for liver failure and small-for-size syn…
-
CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver Failure [Phase 1]
Phase 1 clinical trial assessing the safety and effectiveness of mesenchymal stem cells used in blood purification for liver failure; study …
-
CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)
A National Natural Science Foundation of China–funded clinical trial studies the relationship between resected normal liver parenchymal volu…
-
CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Ex Vivo Perfusion of Gene-Edited Porcine Livers in Patients With Severe Hepatic Failure [EARLY_Phase 1]
An early-phase trial is evaluating ex vivo perfusion of gene-edited porcine livers in patients with severe hepatic failure. The study status…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: TReatment for ImmUne Mediated PathopHysiology [Phase 2]
A Phase 2 clinical trial sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases is recruiting to treat immune-med…
-
CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Empagliflozin in Patients With Cirrhosis and Ascites [Phase 2]
A Phase 2 clinical trial evaluating empagliflozin in patients with cirrhosis and ascites is currently recruiting at Yale University.
-
CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care
A clinical trial at University Hospital Strasbourg is evaluating diagnostic approaches for hemophagocytic lymphohistiocytosis in intensive c…
-
CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: ALSS - DPMAS and Therapeutic Plasma Exchange (TPE), Its Effect on Primary Coagulation, Inflammation and the Function of Vital Organs in ALF or ACLF [NA]
Clinical trial update on ALSS using DPMAS and therapeutic plasma exchange to assess effects on coagulation, inflammation and organ function …
-
CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Abdominal Wall Transplant [NA]
Duke University is sponsoring a recruiting clinical trial evaluating abdominal wall transplantation for patients with abdominal wall defects…
-
CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Standard Volume vs. High Volume Plasma Exchange in Pediatric Acute Liver Failure [NA]
A pediatric clinical trial comparing standard-volume versus high-volume plasma exchange for acute liver failure is currently recruiting.
-
CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Addiction Intervention in Liver Transplantation Candidates [NA]
An ongoing clinical trial in Montpellier is evaluating an addiction intervention for liver transplant candidates; the study is active but no…
-
CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: F573 for Injection for the Treatment of Liver Injury/Failure [Phase 2]
Phase 2 clinical trial update for F573 for Injection in acute liver failure and acute-on-chronic liver failure, currently recruiting.
-
CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial [Phase 1]
Phase 1 clinical trial MARCO (Microbiota Augmentation to Reestablish Commensal Organisms) investigating a microbiota-based therapy for liver…
-
CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Longitudinal Study of Mitochondrial Hepatopathies
The longitudinal study of mitochondrial hepatopathies is currently suspended.
-
CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema [NA]
This clinical trial compares high-volume versus standard-volume plasma exchange in patients with acute liver failure and cerebral edema; the…
-
CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: CytOSorb TreatMent Of Critically Ill PatientS Registry
A Clinical Trials registry update shows that CytoSorbents is recruiting for a registry trial evaluating Cytosorb hemoadsorption in criticall…
-
CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas) [Phase 3]
A Phase 3 clinical trial comparing Custodiol-N solution with Custodiol solution in kidney, liver, and pancreas transplantation is currently …
-
CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Transcriptional Analysis of Mechanisms in Liver Failure and Sepsis
Clinical trial from the University of Cambridge investigating transcriptional mechanisms in acute liver failure and sepsis; the study status…
-
CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: The Efficacy of Intravenous Amino Acids in Reducing the Occurrence of AKI After Live Donor Liver Transplant [NA]
This clinical trial investigates whether intravenous amino acids can reduce acute kidney injury after a live donor liver transplant, and the…
-
CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection [Phase 1, Phase 2]
This clinical trial update describes an investigation into CRISPR-edited HLA donor livers to reduce transplant rejection, with Phase 1 and P…
-
CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Biomarkers in Liver Failure
A University of Edinburgh–sponsored biomarker study on liver failure, covering acute liver failure, acute liver injury, and acute-on-chronic…
-
CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Micro-encapsulated Hepatocyte Intraperitoneal Transplantation in Liver Failure Adults [Phase 1]
Phase 1 clinical trial evaluating micro-encapsulated hepatocytes delivered intraperitoneally for adults with liver failure is currently recr…
-
CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Continuous Renal Replacement Therapy Intensity in Hyperammonemia [NA]
A clinical trial is evaluating the effect of different intensities of continuous renal replacement therapy on hyperammonemia in patients wit…
-
CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Perioperative Use of Amino Acids in Recipients of Orthotopic Liver Transplantation as a Renal Protective Factor [NA]
This clinical trial update describes the perioperative use of amino acids as a renal protective strategy in recipients of orthotopic liver t…