Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-06-23Clinical Trial Update: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function [Phase 1]
A Phase 1 pharmacokinetic/pharmacodynamic safety and tolerability study of dabigatran etexilate in patients with moderate liver impairment c…
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function [Phase 1]
Phase 1 study evaluating the exposure, safety, and tolerability of a single dose of FG-4592 (roxadustat) in subjects with moderately diminis…
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Anidulafungin vs Amphotericin B Safety in High Risk Hepatic Transplant Recipients [Phase 4]
Phase 4 trial comparing safety of anidulafungin versus amphotericin B in high-risk liver transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: A Study to Assess the Effect of Severe Hepatic Impairment on the Pharmacokinetics of Intravenous Conivaptan [Phase 1]
Phase 1 pharmacokinetic study evaluating the effect of severe hepatic impairment on the pharmacokinetics of intravenous conivaptan; the stud…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function [Phase 1]
Phase 1 trial update comparing conivaptan pharmacokinetics in subjects with mild to moderate liver impairment versus those with normal liver…
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CLINICAL_TRIALS trial_result · 2014-04-07Clinical Trial Update: Detection of Hepatocellular Carcinoma (HCC) With Octanoate Breath ID Test Compared to MRI [Phase 2]
Phase 2 trial evaluating octanoate breath test for detecting hepatocellular carcinoma compared with MRI; study terminated with results poste…
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CLINICAL_TRIALS trial_result · 2014-01-17Clinical Trial Update: Kidney and Liver Transplantation in People With HIV
Clinical trial update on kidney and liver transplantation in people with HIV has completed. The study evaluated transplantation outcomes in …
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: Efficacy and Safety of Modified Anti-tubercular Regimens in Treatment of Tuberculosis in Patients With Underlying Compensated and Decompensated Chronic Liver Disease [NA]
A clinical trial update evaluating modified anti-tubercular regimens for tuberculosis in patients with chronic liver disease (compensated an…
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Isoflurane Preconditioning for Liver Resections [NA]
A clinical trial evaluating isoflurane preconditioning during liver resections was terminated, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-11-26Clinical Trial Update: Hepatitis B Vaccine Clinical Trial [Phase 3]
Phase 3 clinical trial of a Hepatitis B vaccine has completed. The update provides no results.
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CLINICAL_TRIALS trial_result · 2013-09-27Clinical Trial Update: Orthotopic Liver Transplantation Using a Living Donor [Phase 4]
A Phase 4 trial of orthotopic liver transplantation from living donors conducted by the University of Chicago has been terminated.
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CLINICAL_TRIALS trial_result · 2013-09-24Clinical Trial Update: Real Time Elastography in Liver Fibrosis
This is a ClinicalTrials.gov entry for a study on Real Time Elastography in liver fibrosis, sponsored by the University of Medicine and Phar…
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CLINICAL_TRIALS trial_result · 2013-08-02Clinical Trial Update: Mycophenolate Mofetil Immunosuppression Without/With Reduced Dose Calcineurin Inhibitor Long After Liver Transplantation [Phase 4]
This clinical trial update reports results from a Phase 4 study comparing mycophenolate mofetil–based immunosuppression with and without red…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating probiotics for minimal hepatic encephalopathy and health-related quality of life. The study …
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Hypovitaminosis D and an Inadequate PTH Response in Chronic Liver Disease Patients [NA]
A clinical trial update indicates the study on hypovitaminosis D and inadequate PTH response in chronic liver disease patients has been term…
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CLINICAL_TRIALS trial_result · 2013-04-18Clinical Trial Update: Polymorphisms of Fibrosis-Relating Genes on Outcome of HCV-Related Chronic Liver Disease [NA]
This clinical trial update reports on polymorphisms of fibrosis-related genes and their association with outcomes in hepatitis C-related chr…
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CLINICAL_TRIALS trial_result · 2013-04-18Clinical Trial Update: Genetic Polymorphisms of Interleukin-1B and TNF-A and HBV-Related Hepatocellular Carcinoma [NA]
This clinical trial update describes associations of interleukin-1B and TNF-α gene polymorphisms with HBV-related hepatocellular carcinoma a…
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetic study evaluating single-dose iloperidone in patients with mild to moderate hepatic impairment compared with healthy …
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Use of N-Acetylcysteine During Liver Procurement [Phase 2]
This ClinicalTrials.gov entry reports the completion of a Phase 2 study evaluating the use of N-acetylcysteine during liver procurement.
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CLINICAL_TRIALS trial_result · 2013-01-29Clinical Trial Update: Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease [Phase 1, Phase 2]
This clinical trial update reports on the pharmacokinetics of alitretinoin (9-cis-retinoic acid) in patients with hepatic disease, spanning …
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia [Phase 2]
Phase 2 study of PEG-Intron in hereditary hemorrhagic telangiectasia was terminated; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Randomized Controlled Trial of ImmuKnow in Liver Transplantation [NA]
A randomized controlled trial evaluating ImmuKnow to guide immunosuppression in liver transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Resting Energy Expenditure in Patients on the Waiting List for Liver Transplantation
This study reports results on resting energy expenditure in patients awaiting liver transplantation, contributing to understanding metabolic…
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: Patterns of Early Hepatitis C Virus Decline Predict the Outcome of Interferon Therapy (sIFN-pred2)
This clinical trial update investigates whether early declines in hepatitis C virus levels can predict the outcome of interferon therapy.
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CLINICAL_TRIALS trial_result · 2012-12-18Clinical Trial Update: Colesevelam Versus Placebo in Cholestatic Pruritus [Phase 2, Phase 3]
A Phase 2/3 trial comparing colesevelam to placebo for cholestatic pruritus in chronic liver disease has completed.