Liposarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma [Phase 2]
Open-label Phase 2 study of IMC-A12 (cixutumumab) in advanced sarcomas. Results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or Leiomyosarcoma [Phase 3]
This clinical trial update notes the completion of a Phase 3 study evaluating trabectedin (YONDELIS) in patients with locally advanced or me…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Detection of Circulating Tumor Cells in Patients With Sarcomas
An update on a clinical trial investigating detection of circulating tumor cells in patients with sarcomas, including Leiomyosarcoma, Pleomo…
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FDA approval · 2018-06-29FDA Approved: YONDELIS — Supplemental Application (Janssen Products, LP)
FDA approved a supplemental application for YONDELIS (trabectedin) from Janssen Products, LP.
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: PD0332991 (Palbociclib) in Patients With Advanced or Metastatic Liposarcoma [Phase 2]
Phase 2 trial results of palbociclib in patients with advanced or metastatic liposarcoma were posted, detailing outcomes from the study.
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of ribociclib in patients with advanced liposarcoma, including well-differentiated…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Bevacizumab and Radiation Therapy for Sarcomas [Phase 2]
Phase 2 trial evaluating bevacizumab with radiation therapy in soft tissue sarcomas completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update for romidepsin (depsipeptide) in patients with metastatic or unresectable soft tissue sarcoma, with results po…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: A Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohort in Virally Mediated Cancers and Liposarcoma [Phase 1]
Phase 1 study of oral azacitidine in combination with romidepsin in advanced solid tumors, with expansion cohorts in virally mediated cancer…
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CLINICAL_TRIALS trial_result · 2017-02-13Clinical Trial Update: Troglitazone in Treating Patients With Liposarcoma [Phase 2]
A Phase 2 clinical trial studying troglitazone for liposarcoma has completed.
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Retrospective Evaluation of Liposarcoma
A completed retrospective evaluation of liposarcoma from a clinical trial conducted at the Technical University of Munich.
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Alisertib in Treating Patients With Advanced or Metastatic Sarcoma [Phase 2]
A Phase 2 trial update of alisertib in patients with advanced or metastatic soft tissue sarcomas, including myxofibrosarcoma and several his…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma [Phase 2]
Phase II clinical trial evaluating the efficacy and safety of ribociclib in patients with advanced well-differentiated or dedifferentiated l…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5045337 in Patients With Liposarcomas Prior to Debulking Surgery [Phase 1]
A Phase 1 study evaluating RO5045337 in patients with liposarcoma prior to debulking surgery has completed.
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Liposarcoma [Phase 2]
Phase 2 study of pazopanib in patients with surgically unresectable or metastatic liposarcoma completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma [Phase 1]
This Phase 1 trial evaluated the combination of cixutumumab and doxorubicin in patients with unresectable, locally advanced, or metastatic s…
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CLINICAL_TRIALS research · 2016-05-17Clinical Trial Update: Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
A completed clinical trial update studying gene expression in tissue samples from children and adolescents with soft tissue sarcomas to bett…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma [Phase 3]
A Phase 3 trial compared trabectedin to dacarbazine in patients with advanced liposarcoma or leiomyosarcoma; results were posted in January …
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FDA approval · 2015-11-18FDA Approved: HALAVEN — Supplemental Application (BSP Pharmaceuticals SpA)
FDA approved a supplemental application for HALAVEN (eribulin mesylate) from BSP Pharmaceuticals SpA.
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating saracatinib (AZD0530) in adults with recurrent, locally advanced, or metastatic soft tissue sarcoma has completed…
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable Liposarcoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating nelfinavir mesylate in adults with liposarcoma (recurrent, metastatic, or unresectable soft tissue sarcoma) was t…
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED) [Phase 2]
This update reports the completion of a Phase 2 trial of ridaforolimus (AP23573/MK-8669), an mTOR inhibitor, in patients with advanced sarco…
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CLINICAL_TRIALS trial_result · 2014-12-16Clinical Trial Update: Combination Therapy of Gemcitabine and Trabectedin in L-sarcomas [Phase 1]
Phase 1 trial evaluating the combination of gemcitabine and trabectedin in leiomyosarcoma and liposarcoma has completed. The study explored …
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Autologous T Cells and Cyclophosphamide in Treating Patients With Soft Tissue Sarcoma That is Metastatic or Cannot Be Removed By Surgery [Phase 1]
A Phase 1 trial of autologous T cells combined with cyclophosphamide in adults with metastatic or unresectable soft tissue sarcoma (includin…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer [Phase 2]
This Phase 2 trial evaluated two dosing schedules of trabectedin in patients with advanced liposarcoma or leiomyosarcoma; the study has comp…