Lipodystrophy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Effects of Meal Macronutrients on Postprandial Lipids [Phase 2]
Phase 2 clinical trial update by the National Institute of Diabetes and Digestive and Kidney Diseases evaluating how meal macronutrients inf…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy [Phase 2]
Phase 2 compassionate-use update for metreleptin in previously treated people with partial lipodystrophy; the study is currently ACTIVE_NOT_…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: The LD Lync Study - Natural History Study of Lipodystrophy Syndromes
The LD Lync Study is a natural history study of lipodystrophy syndromes and is currently recruiting at the University of Michigan.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy
This clinical trial update describes the natural history of pregnancy and pregnancy outcomes in individuals with lipodystrophy who are treat…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Expanded Access to REGN4461 for Patients With Diseases Associated With Deficient Leptin Signaling
Regeneron announced expanded access to REGN4461 for patients with diseases tied to deficient leptin signaling, including lipodystrophy and m…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: The Cleveland Cardiometabolic Cohort
This clinical trials entry reports on the Cleveland Cardiometabolic Cohort (NCT03059121), sponsored by University Hospitals Cleveland Medica…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Registry for Patients With Lipodystrophy
The University of Ulm is sponsoring a registry study for patients with lipodystrophy, including acquired and congenital forms. The study is …
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EMA approval · 2025-11-03EMA Authorised: Myalepta (Metreleptin) — Chiesi Farmaceutici S.p.A.
EMA authorised Myalepta (metreleptin) for lipodystrophy, including familial partial lipodystrophy, with orphan medicine designation; the mar…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Hemoglobin Level, Coagulopathy Profile and Electrolyte Balance
A completed clinical trial update reporting on hemoglobin levels, coagulopathy profile, and electrolyte balance in lipodystrophy and obesity…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE" [NA]
Clinical trial update for SIDERALE evaluating susceptibility to infectious diseases in obesity, including obesity and related metabolic cond…
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management [NA]
Completed clinical trial evaluating carotid Doppler peak velocity variation during liposuction fluid management in lipodystrophy patients.
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Performance and Safety of the Lipo-transfer Cannulas in Patients Underlying Lipofilling Treatment
A completed clinical trial evaluating the performance and safety of lipo-transfer cannulas used in lipofilling for lipodystrophy-related def…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids [Phase 3]
Phase 3 trial evaluating safety and effectiveness of fenofibrate and pravastatin in HIV-positive patients with abnormal blood lipids; study …
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CLINICAL_TRIALS trial_result · 2021-04-26Clinical Trial Update: Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH. [Phase 3]
Phase 3 clinical trial evaluating berberine in combination with antiretroviral therapy for metabolic syndrome in people living with HIV; cur…
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CLINICAL_TRIALS trial_result · 2021-02-11Clinical Trial Update: The PREFORM Study: Rotational Fractional Resection for Submental Contouring [NA]
Completed clinical trial update for the PREFORM Study on rotational fractional resection for submental contouring; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: CONFORM: Rotational Fractional Resection for Submental Contouring [NA]
A completed clinical trial (CONFORM) evaluating rotational fractional resection for submental contouring in conditions of skin laxity and li…
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CLINICAL_TRIALS trial_result · 2020-11-17Clinical Trial Update: Clinical Evaluation of Venus Versa Octipolar Applicator for Reduction of Abdomen Circumference [NA]
A terminated clinical trial evaluating the Venus Versa Octipolar Applicator for abdomen circumference reduction in lipodystrophy; results po…
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CLINICAL_TRIALS trial_result · 2020-10-20Clinical Trial Update: Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension [Phase 2]
Phase 2 trial assessing efficacy, safety, and tolerability of ISIS 304801 in partial lipodystrophy with an open-label extension; results com…
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CLINICAL_TRIALS trial_result · 2019-11-13Clinical Trial Update: Short-term Effects of Leptin in People With Lipodystrophy [Phase 2]
A Phase 2 clinical trial evaluating short-term effects of leptin in people with lipodystrophy has completed and posted results.
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Therapeutic Approaches to HAART-Induced Lipodystrophy [Phase 2]
Phase 2 clinical trial update on therapeutic approaches to HAART-induced lipodystrophy in HIV infection.
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Cholic Acid for Hepatic Steatosis in Lipodystrophy [Phase 2]
Phase 2 clinical trial evaluating cholic acid for hepatic steatosis in lipodystrophy has completed, with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients [Phase 3]
Phase 3 trial evaluating tesamorelin for HIV-associated lipodystrophy has completed and posted results. The study investigates treatment of …
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Prevalence of Lipodystrophy Syndrome and Its Role as Cause of Metabolic Disturbances
This update reports on the prevalence of lipodystrophy syndrome and its role as a cause of metabolic disturbances based on the completed NCT…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Quality of Life, Sleep, and Biomarkers in People With HIV/AIDS [NA]
A completed clinical trial assessing quality of life, sleep, and biomarkers in people with HIV/AIDS.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy [Phase 2]
A Phase 2 clinical trial evaluating metreleptin for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis associated with lipody…