Leukemia
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Technology-Assisted Yoga and Exercise on Neuropathy and Pain in Children With Leukemia [NA]
A completed clinical trial evaluating technology-assisted yoga and exercise for reducing neuropathy and pain in children with leukemia.
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Precision Medicine for Every Child With Cancer
A clinical trial update for a pediatric precision medicine study sponsored by ANZCHOG, currently recruiting across various pediatric cancers…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Incidence and Risks Factors of CMV Reactivation in Patients Receiving of CAR-T Cells for Acute Leukemia and Lymphoma Relapse, a Cohort Study Analysis
A cohort-study analysis evaluating the incidence and risk factors of CMV reactivation in patients receiving CAR-T cell therapy for relapse o…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab) [Phase 2]
Phase 2 clinical trial PRONTO studies prophylactic versus on-demand use of tocilizumab, currently recruiting.
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: False Positive Peripheral Blood Culture in Children With Leukaemia: A Prevalence Study
A completed prevalence study examining how often peripheral blood cultures yield false positives in children with leukemia and the potential…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Children and Adolescents With Leukemia, Brain Tumors, and Sarcomas
The clinical trial update reports completion of a study evaluating treatments for leukemia, brain tumors, and sarcomas in children and adole…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Validating Pain Scales in Children and Young Adults
National Cancer Institute completed a clinical trial focused on validating pain scales in children and young adults with sickle cell disease…
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Providing Web-based Training to Parents Of Children With Leukemia [NA]
The clinical trial evaluating web-based training for parents of children with leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy [NA]
A completed clinical trial evaluating the feasibility of a digital health coaching program for individuals after CAR T-cell therapy.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Study of ONO-7475 in Patients With Acute Leukemias [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of ONO-7475 in patients with acute leukemia and myelodysplastic syndromes,…
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CLINICAL_TRIALS other · 2024-05-01Clinical Trial Update: PUMA (Paediatric Osseous Marrow Assessment)
A pediatric leukemia study called PUMA (Paediatric Osseous Marrow Assessment) is currently recruiting in the United Kingdom, sponsored by th…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Livertoxcicity in Acute Leukemia Patients During Chemotherapy Treatment
This clinical trial update discusses liver toxicity risks in acute leukemia patients undergoing chemotherapy; the study is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: A Study of PTX-200 (Triciribine) Plus Cytarabine in Refractory or Relapsed Acute Leukemia [Phase 1, Phase 2]
Phase 1/2 trial investigating PTX-200 (triciribine) with cytarabine in refractory or relapsed acute leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: RIC Regimen for Elderly or High Comorbidity Burden Patients Receiving Haplo-HSCT [Phase 2]
Phase 2 trial evaluating a reduced-intensity conditioning regimen for elderly or high-comorbidity patients undergoing haploidentical hematop…
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a combination of sirolimus, abatacept, and mycophenolate mofetil to prevent aGraft-versus-Host Disease…
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia. [Phase 1]
Phase 1 trial of clofarabine with low-dose total body irradiation as a preparative regimen for stem cell transplant in leukemia shows comple…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Alemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic Lymphohistiocytosis [Phase 2]
Phase 2 trial evaluating alemtuzumab or tocilizumab in combination with etoposide and dexamethasone for adults with hemophagocytic lymphohis…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801) [Phase 3]
Phase 3 trial comparing TAC/MTX versus TAC/MMF/PTCY for graft-versus-host disease prevention and microbiome/immune reconstitution in patient…
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Empirical Versus Preemptive Antifungal Therapy [Phase 3]
Phase 3 trial comparing empirical versus preemptive antifungal therapy in patients with fungal infection and leukemia/myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: Use of GnRHa During Chemotherapy for Fertility Protection [Phase 3]
Phase 3 trial investigating GnRHa during chemotherapy to protect fertility in cancer patients; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion [Phase 2]
This entry details a Phase 2 expansion study of ruxolitinib for chronic myelomonocytic leukemia, with results posted in October 2023.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Busulfan, Etoposide, and Total-Body Irradiation in Treating Patients Undergoing Donor Stem Cell or Bone Marrow Transplant for Advanced Hematologic Cancer [Phase 2]
Phase 2 study evaluating a conditioning regimen of busulfan, etoposide, and total-body irradiation for patients undergoing donor stem cell o…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: 90Y-labelled Anti-CD66 ab in Childhood High Risk Leukaemia [Phase 2]
Phase 2 trial update for a 90Y-labelled anti-CD66 antibody in childhood high-risk leukemia is reported.
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CLINICAL_TRIALS trial_result · 2023-08-15Clinical Trial Update: CLAGE Sequential With Flu-Bu Conditioning for Refractory Acute Leukemia [Phase 2]
Phase 2 clinical trial update for CLAGE sequential conditioning with Flu-Bu in refractory acute leukemia undergoing allogeneic stem cell tra…
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CLINICAL_TRIALS withdrawal · 2023-08-03Clinical Trial Update: H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis [Phase 3]
Phase 3 clinical trial for Langerhans Cell Histiocytosis (H-9926-LCH III) has been withdrawn.