Leukemia
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CLINICAL_TRIALS trial_result · 2012-11-12Clinical Trial Update: Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease [Phase 1]
Phase 1 trial evaluating donor stem cell transplantation in young patients with congenital amegakaryocytic thrombocytopenia, leukemia, myelo…
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 trial update evaluating zoledronic acid to prevent osteoporosis in patients undergoing donor stem cell transplantation. The study in…
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: Phase II Study of the Efficacy and Toxicity of Ontak(Registered Trademark) (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia [Phase 2]
Phase II study of denileukin diftitox (Ontak) in adult T-cell leukemia was terminated; results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: Donor Bone Marrow Transplant in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders [Phase 2]
A Phase 2 clinical trial evaluating donor bone marrow transplantation for various hematologic diseases has completed.
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CLINICAL_TRIALS trial_result · 2012-10-10Clinical Trial Update: Total-Body Irradiation, Fludarabine, and Alemtuzumab Followed By Stem Cell Transplant in Treating Patients With Myeloproliferative Disorder, MS, AML, or CML [Phase 2]
Phase 2 clinical trial evaluating total-body irradiation with fludarabine and alemtuzumab followed by stem cell transplant in patients with …
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CLINICAL_TRIALS trial_result · 2012-10-04Clinical Trial Update: Epoetin Alfa in Treating Patients With Anemia Who Are Undergoing Chemotherapy for Cancer [Phase 2]
Phase 2 trial evaluating epoetin alfa for treating chemotherapy-induced anemia in cancer patients; the study has completed.
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CLINICAL_TRIALS trial_result · 2012-10-04Clinical Trial Update: Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer [NA]
A clinical trial update reports completion of a donor stem cell transplant study in older or frail patients with hematologic cancers.
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer [Phase 2]
Phase 2 trial evaluating early administration of anti-thymocyte globulin (ATG) followed by cyclophosphamide, busulfan and fludarabine as a c…
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CLINICAL_TRIALS trial_result · 2012-09-26Clinical Trial Update: Arsenic Trioxide for Induction Therapy of Adult Patients With Leukemia [Phase 2]
A Phase 2 trial evaluating arsenic trioxide as induction therapy for adult leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: Phase II Trial With Correlative Laboratory Studies of Single Agent Irinotecan (Camptosar CPT-11) [Phase 2]
A completed Phase II trial of single-agent irinotecan (Camptosar) in leukemia and lymphoma, with correlative laboratory studies.
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: A Phase I/II Study of Induction Chemotherapy With Daunorubicin, Cytarabine, Topotecan and Etoposide [Phase 1, Phase 2]
This document reports the completion of a Phase I/II trial of an induction chemotherapy regimen consisting of daunorubicin, cytarabine, topo…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count [Phase 3]
Phase 3 trial update on preventing infection in patients with hematologic cancers and leukopenia-related fever; the study has been completed…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer [NA]
A clinical trial comparing moxifloxacin with ciprofloxacin plus amoxicillin for fever and neutropenia in cancer patients was terminated.
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CLINICAL_TRIALS trial_result · 2012-09-14Clinical Trial Update: A Study of the Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of the histone-deacetylase inhibitor JNJ-26481585 in patients with advanced or refractory leukemia or myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2012-09-06Clinical Trial Update: Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain [Phase 3]
Phase 3 clinical trial evaluating an opioid titration order sheet versus standard care for cancer-related pain; the study is completed with …
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CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies [Phase 2]
Phase 2 hematopoietic cell transplantation trial in pediatric patients with hematologic malignancies has completed and results have been pos…
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases [Phase 2]
Phase 2 trial assessing megadose CD34+ selected progenitor cell transplantation in patients with advanced hematologic malignancies (leukemia…
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CLINICAL_TRIALS trial_result · 2012-08-02Clinical Trial Update: 2-Chlorodeoxyadenosine and Cytarabine in Patients With Idiopathic Hypereosinophilic Syndrome (HES) [Phase 2]
Phase 2 trial evaluating cladribine (2-Chlorodeoxyadenosine) in combination with cytarabine for idiopathic hypereosinophilic syndrome has co…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Pharmacokinetic Evaluation of Rasburicase in Patients With Leukemia and/or Lymphoma at High Risk of TLS [Phase 1, Phase 2]
The study reports pharmacokinetic evaluation of rasburicase in patients with leukemia or lymphoma who are at high risk of tumor lysis syndro…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: FTS Study in Patients With Advanced Hematologic Malignancies [Phase 1]
Phase I study update of FTS in patients with advanced hematologic malignancies, including myelodysplastic syndromes and leukemia; the trial …
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Use and Tolerability of Imatinib Mesylate (Gleevec) in Leukemia Patients [NA]
A completed study assessing the use and tolerability of imatinib mesylate (Gleevec) in patients with leukemia.
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Study of Weekly Clofarabine for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 study evaluating weekly clofarabine for relapsed/refractory chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Oral Valganciclovir Versus Valacyclovir [Phase 2]
A Phase 2 clinical trial comparing oral valganciclovir versus valacyclovir in patients with chronic lymphocytic leukemia and leukemia, which…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating decitabine with peripheral stem cell transplantation in patients relapsed after bone marrow transplantat…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Azacitidine Maintenance Therapy After Allogeneic Bone Marrow Transplantation (Allo BMT) [Phase 1]
This report notes the completion of a Phase 1 clinical trial evaluating azacitidine as maintenance therapy after allogeneic bone marrow tran…