Leukemia
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Early Versus Late Stopping of Antibiotics in Adults With High-risk Hematological Malignancies/Receiving Cellular Therapies and Fever [NA]
This clinical trial update describes a study comparing early versus late stopping of antibiotics in adults with high-risk hematologic cancer…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions [NA]
A pediatric leukemia study investigates non-pharmacologic interventions (transcutaneous acupoints electrical stimulation and auricular acupr…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment [Phase 1, Phase 2]
Clinical trial update for neratinib in children and young adults with cancer, focusing on safety and dose finding in Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: GMALL Registry and Collection of Biomaterial: Prospective Data Collection Regarding Diagnosis, Treatment and Outcome of Adult Acute Lymphoblastic Leukemia (ALL) Patients and Related Diseases Associated With a Prospective Collection of Biomaterial
A prospective registry study collecting diagnosis, treatment, and outcome data for adults with acute lymphoblastic leukemia and related dise…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Efficacy of Dose-Adjusted Regimen on Survival in Frail Adults With Acute Lymphoblastic Leukemia
This update describes a clinical trial evaluating a dose-adjusted regimen for frail adults withacute lymphoblastic leukemia. It aims to asse…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group
Update on enrollment for the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group; the network remains active but is no…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: ALL Backbone in AYAs [Phase 2]
Phase 2 clinical trial evaluating the ALL Backbone regimen in adolescents and young adults with acute lymphoblastic leukemia; the study is c…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating allogeneic stem cell transplantation with alpha/beta T and B cell depletion for hematologic malignancies; …
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
This MD Anderson Cancer Center study is developing a video game to improve outcomes for stem cell transplant survivors, with recruitment ong…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
This ClinicalTrials.gov update describes an ongoing study that collects tissue, blood, and body fluid samples from patients with hematologic…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: YASU Research Registry: For Young Adults With Cancer
Clinical trial update indicating termination of the YASU Research Registry for young adults with cancer, listing several cancer conditions i…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Umbilical Cord Blood Transplantation From Unrelated Donors
This is an ongoing clinical trial evaluating umbilical cord blood transplantation from unrelated donors for hematologic diseases. The study …
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating a two-step anti-thymocyte globulin (ATG) regimen to prevent acute graft-versus-host disease after myeloablative all…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig) [Phase 2, Phase 3]
Clinical trial update for the Stop Ig study, assessing whether antibiotic therapy or immunoglobulin use affects infection management and dec…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Dosing Immunoglobulin (Dose Ig) [Phase 2, Phase 3]
A Monash University trial is testing antibiotic therapy or intravenous immunoglobulin dosing to prevent infections in hematologic cancer pat…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT) [Phase 2, Phase 3]
A hematology platform trial (RATIONAL-PT) is evaluating the roles of antibiotic therapy or immunoglobulin for infections in patients with he…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)
The document announces a new clinical trial called HALO-SCT, assessing high-altitude observation in stem cell transplantation. It is current…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients [NA]
A pilot lifestyle intervention trial is recruiting patients with myeloproliferative neoplasms and leukemia at Massachusetts General Hospital…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation. [NA]
This clinical trial update outlines a study evaluating whether an early warning system affects prognosis for patients with hematological mal…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Metformin Inhibits DNMT3A Clonal Hematopoiesis in Acute Leukemia [Phase 1]
A Phase 1 trial is investigating whether metformin can inhibit DNMT3A-mutant clonal hematopoiesis in acute leukemia; the study is not yet re…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Feasibility of an Adapted Sports Program Based on Fencing to Reduce Physical Deconditioning in Adult Hematology Patients [NA]
An update on the feasibility of an adapted fencing-based sports program to counter physical deconditioning in adults with leukemia or lympho…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients [Phase 1]
Phase 1 trial evaluating Itacitinib with high-dose posttransplantation cyclophosphamide in older patients. The study is currently ACTIVE_NOT…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: A Clinical Study of BT02 in Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1, Phase 2]
Biotroy Therapeutics is conducting a Phase 1/2 study of BT02 for relapsed or refractory hematologic malignancies, with recruitment not yet s…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: HEME Home Transfusion Program [NA]
Clinical trial update indicates that the HEME Home Transfusion Program is currently recruiting for hematologic conditions including leukemia…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT [Phase 1]
A Phase 1 trial evaluating total body irradiation delivered with IMRT (VMAT or Tomotherapy) to prevent pulmonary toxicities in patients unde…