Left Ventricular Systolic Dysfunction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036) [Phase 2, Phase 3]
Pediatric Phase 2/3 trial evaluating vericiguat for heart failure due to left ventricular systolic dysfunction, assessing efficacy, safety, …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction [Phase 3]
A Phase 3 trial to evaluate finerenone versus placebo on standard treatment for safety, pharmacokinetics, and efficacy in children with hear…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction [Phase 3]
A Phase 3 clinical trial to evaluate long-term safety of finerenone in children and young adults with heart failure and left ventricular sys…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead [NA]
A trial update on the Cardiac Microcurrent (C-MIC) System using a less invasively placed left ventricular lead; the study is currently recru…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass [NA]
A clinical trial comparing ketamine-lidocaine versus ketamine-fentanyl for induction of anesthesia in patients with left ventricular systoli…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study
A pilot study is evaluating multimodality imaging to assess left ventricular remodeling in mitral regurgitation patients with left ventricul…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Performance and Safety of the Cardiac Microcurrent Therapy System [NA]
This clinical trial update reports on the performance and safety of a Cardiac Microcurrent Therapy System in patients with Left ventricular …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: AI-Enabled Electrocardiogram-Guided Guideline-Directed Medical Therapy on Incident Left Ventricular Dysfunction: A Target Trial Emulation Study [NA]
This document reports a target trial emulation study evaluating an AI-enabled ECG-guided approach to initiating guideline-directed medical t…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Hybrid Ablation of Atrial Fibrillation in Heart Failure [NA]
A clinical trial evaluating a hybrid ablation approach for atrial fibrillation in patients with heart failure is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure [Phase 4]
Phase 4 clinical trial evaluating the effect of oral sucrosomal iron on exercise capacity and quality of life in patients with chronic heart…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: The C-MIC-II Follow-Up Study [NA]
The C-MIC-II Follow-Up Study sponsored by Berlin Heals GmbH is currently recruiting. It targets patients with left ventricular systolic dysf…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: AI-based Prediction of Cardiac Function Using Echocardiography and Body Composition Data (ECHO-FIT Study)
A Yonsei University-sponsored clinical trial is evaluating AI-driven prediction of cardiac function from echocardiography and body compositi…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Adherence to Cied Implantation Guidelines and Cardiac Rehabilitation
This clinical trial update reports adherence to guidelines for Cardiac Implantable Electronic Device (CIED) implantation and cardiac rehabil…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: LifeVest Safety and Efficacy in Real Life Settings in France
This clinical trial evaluated the LifeVest wearable defibrillator's safety and efficacy in real-life settings in France. Results were posted…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Artificial Intelligence-assisted Diagnosis and Prognostication in Low Ejection Fraction Using Electrocardiograms [NA]
Completed clinical trial evaluating AI-assisted diagnosis and prognostication for left ventricular systolic dysfunction using electrocardiog…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: The SMART-LV Pilot Study [NA]
The SMART-LV Pilot Study sponsored by Yale University has completed. It concerns left ventricular systolic dysfunction.
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CLINICAL_TRIALS research · 2022-04-04Clinical Trial Update: Heart Rate Response to Regadenoson and Sudden Cardiac Death [NA]
Clinical trial update on heart rate response to regadenoson and its relation to sudden cardiac death in patients with left ventricular systo…
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Phase IIb Safety and Efficacy Study of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Moderate Chronic Kidney Disease Alone [Phase 2]
Phase IIb study evaluating BAY94-8862 for safety and efficacy in worsening chronic heart failure with left ventricular systolic dysfunction,…
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CLINICAL_TRIALS trial_result · 2021-05-25Clinical Trial Update: Effects of Linagliptin on Left Ventricular Myocardial DYsfunction in Patients With Type 2 DiAbetes Mellitus and Concentric Left Ventricular Geometry [Phase 3]
Phase 3 trial investigating the effects of linagliptin on left ventricular dysfunction in patients with type 2 diabetes and concentric left …
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CLINICAL_TRIALS trial_result · 2021-05-17Clinical Trial Update: COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure [Phase 2]
Phase 2 trial update for COSMIC-HF evaluating an oral myosin activator for heart failure; results completed and posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: STem cElls Mobilization in Acute Myocardial Infarction Outcome Trial [Phase 3]
Phase 3 trial investigating stem cell mobilization in acute myocardial infarction was terminated.
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CLINICAL_TRIALS research · 2020-07-09Clinical Trial Update: Sleep-Disordered Breathing in Heart Failure - The SchlaHF-Registry
A completed clinical trial registry update on sleep-disordered breathing in heart failure (SchlaHF-Registry) with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass [Phase 3]
Phase 3 trial evaluating levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary b…
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CLINICAL_TRIALS research · 2017-06-28Clinical Trial Update: NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction [Phase 2]
Phase 2 clinical trial update for NP202 in treating post-ST-elevation myocardial infarction–related left ventricular systolic dysfunction. T…
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System [Phase 3]
Clinical trial update on a pivotal Phase 3 study of the Parachute Implant System for congestive heart failure with left ventricular systolic…