Left Ventricular Dysfunction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure [Phase 2]
This update reports that a Phase 2 trial evaluating carperitide in congestive heart failure has completed. The snippet does not provide tria…
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CLINICAL_TRIALS trial_result · 2016-11-03Clinical Trial Update: Tricuspid Regurgitation Study [Phase 4]
A Phase 4 clinical trial studying tricuspid regurgitation and related ventricular dysfunction has completed.
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery [Phase 3]
A Phase 3 confirmatory trial of IK-3001 in Japanese patients with peri-/postoperative pulmonary hypertension associated with cardiac surgery…
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Validation of the Gated Blood Pool SPECT: ERNA vs 3D Echo
A completed study validating gated blood pool SPECT (ERNA) against 3D echocardiography for assessing left ventricular function in congestive…
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CLINICAL_TRIALS research · 2016-05-05Clinical Trial Update: Effects a Rehabilitation Program in Patients With Left Ventricular Dysfunction After Coronary Artery Bypass Grafting [NA]
This trial entry reports an update on a clinical study evaluating the effects of a rehabilitation program in patients with left ventricular …
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FDA approval · 2016-04-12FDA Approved: ENALAPRIL MALEATE — Supplemental Application (ScieGen Pharmaceuticals, Inc.)
The FDA approved a supplemental application for enalapril maleate from ScieGen Pharmaceuticals, Inc. (ANDA 075178).
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CLINICAL_TRIALS trial_result · 2016-04-08Clinical Trial Update: Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum
This clinical trial update announces the completion of a study evaluating transvenous left ventricular septum pacing via the interventricula…
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CLINICAL_TRIALS withdrawal · 2016-03-30Clinical Trial Update: Exercise Training in Treating Diastolic Heart Failure [NA]
Clinical trial NCT02155842 evaluating exercise training for diastolic heart failure was withdrawn.
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Dual Site Left Ventricular (LV) Pacing [NA]
The update reports termination of a dual-site left ventricular pacing trial and notes that results were posted in March 2016.
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use [NA]
Electrical stimulation reportedly improved exercise tolerance in patients with advanced heart failure who require continuous dobutamine.
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: INcrease Of VAgal TonE in CHF [Phase 3]
A Phase 3 trial evaluating increasing vagal tone in heart failure has been terminated.
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CLINICAL_TRIALS research · 2015-11-30Clinical Trial Update: Rate RESPONSIVe Pacing in Patients With Permanent AF Underwent AV Node ABLation and bivEntricular Pacing (RESPONSIBLE) [NA]
Completed clinical trial update on rate-responsive pacing in patients with permanent atrial fibrillation after AV node ablation and biventri…
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH. [Phase 4]
Phase 4 trial update characterizes left ventricular strain patterns in patients with mildly elevated pulmonary capillary wedge pressure and …
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CLINICAL_TRIALS research · 2015-10-12Clinical Trial Update: Non-invasive Blood Pressure and Cardiac Output Measurement by Using Applanation Tonometry
This entry provides an update on a clinical trial evaluating non-invasive blood pressure and cardiac output measurement using applanation to…
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure [Phase 3]
A Phase 3 trial evaluating hydralazine/isosorbide dinitrate versus placebo in African patients admitted with acute heart failure; the curren…
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FDA approval · 2015-05-01FDA Approved: ENALAPRIL MALEATE — Supplemental Application (ScieGen Pharmaceuticals, Inc.)
The FDA approved a supplemental application for enalapril maleate from ScieGen Pharmaceuticals, indicating continued/expanded authorization …
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView. [Phase 4]
Phase 4 open-label study assessing the test-retest reproducibility of quantitative myocardial uptake measurements using AdreView (I-123 MIBG…
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Mesenchymal Stem Cells and Myocardial Ischemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating mesenchymal stem cells for chronic myocardial ischemia and left ventricular dysfunction has completed.
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CLINICAL_TRIALS trial_result · 2014-06-23Clinical Trial Update: Effects of Viagra on Heart Function in Patients With Heart Failure [Phase 4]
A Phase 4 trial evaluated the effects of sildenafil (Viagra) on heart function in patients with heart failure and left ventricular dysfuncti…
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics [Phase 2]
Phase 2 trial evaluating riociguat's effects on hemodynamics and left-ventricular contractility/relaxation in patients with pulmonary hypert…
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CLINICAL_TRIALS trial_result · 2013-12-23Clinical Trial Update: Pilot Study of Remote Ischemic Preconditioning in Heart Failure [NA]
A pilot study evaluating remote ischemic preconditioning in patients with heart failure has been completed.
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) [Phase 2]
A Phase 2 trial (FOCUS Study) examined autologous stem cell therapy for adults with ischemic cardiomyopathy; the study completed and results…
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Use of Adult Autologous Stem Cells in Treating People Who Have Had a Heart Attack (The TIME Study) [Phase 2]
Phase 2 TIME Study evaluated autologous adult stem cell therapy in patients who had a heart attack with left ventricular dysfunction. The tr…
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CLINICAL_TRIALS trial_result · 2013-01-30Clinical Trial Update: Patient's Management Receiving Eplerenone Therapy
Completed clinical trial evaluating management of patients receiving eplerenone therapy in left ventricular dysfunction after myocardial inf…
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CLINICAL_TRIALS research · 2012-12-27Clinical Trial Update: IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting
This is a completed registry study (IMPROVE HF) evaluating the use of evidence-based heart failure therapies in outpatient settings, with re…