Knee Osteoarthritis
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Pivotal Study to Evaluate Efficacy and Safety of SP5M002 Inj. as Compared to Synovian Inj. in Patients With Mild to Moderate Knee Osteoarthritis [Phase 3]
A Phase 3 pivotal trial evaluating SP5M002 injectable versus Synovian injectable in mild-to-moderate knee osteoarthritis is ongoing; the stu…
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Motor Imagery and Action Observation in Patients With Knee Osteoarthritis [NA]
This report provides an update on a clinical trial evaluating motor imagery and action observation for knee osteoarthritis; the study status…
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Exercise-induced Hypoalgesia in Patients With Knee Osteoarthritis [NA]
A clinical trial update for a study on exercise-induced hypoalgesia in knee osteoarthritis patients, currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Total Knee Arthroplasty Using an Active Robotic System [NA]
This document notes an ongoing clinical trial evaluating a robotic-assisted total knee arthroplasty system for knee osteoarthritis, currentl…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Measuring Synovial Fluid Components [NA]
An update on a clinical trial evaluating measurements of synovial fluid components in knee osteoarthritis; no phase, status, or results info…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis [NA]
This clinical trial update reports that the study evaluating adipose-derived stem cells for knee osteoarthritis is currently in recruitment.…
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: Efficacy of Different Doses of Pregabalin as a Multimodal Analgesic Agent in Postoperative Pain Control After Total Knee Arthroplasty [Phase 4]
Phase 4 clinical trial evaluating different doses of pregabalin as a multimodal analgesic for postoperative pain control after total knee ar…
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of 2ccPA in Patients With Symptomatic Knee Osteoarthritis [Phase 1, Phase 2]
A clinical trial update evaluates the safety and efficacy of 2ccPA for symptomatic knee osteoarthritis in Phase 1/2.
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Comparison of Ultrasound-Guided Perimeniscal Steroid and 5% Dextrose Injections in Knee Osteoarthritis [Phase 4]
Phase 4 trial comparing ultrasound-guided perimeniscal steroid injections with 5% dextrose injections for knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Comparison of Postoperative Pain Score Between Perioperative Intravenous Ketamine and Placebo in Patients Undergoing Unilateral Total Knee Arthroplasty Under General Anesthesia [Phase 4]
Phase 4 trial comparing postoperative pain scores with perioperative intravenous ketamine versus placebo in unilateral total knee arthroplas…
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: ESPB vs iPACK+ACB in Total Knee Arthroplasty [Phase 4]
Phase 4 clinical trial comparing erector spinae plane block (ESPB) versus iPACK+anterior confirgurational block (ACB) in total knee arthropl…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia [Phase 4]
Phase 4 trial evaluating virtual reality hypnosis as an adjunct for patients undergoing knee arthroplasty under spinal anesthesia; study com…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Extended Postoperative Oral Tranexamic Acid in Knee Replacement [Phase 4]
A Phase 4 clinical trial update on extended postoperative oral tranexamic acid in knee replacement, focusing on knee osteoarthritis and post…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis [Phase 4]
Phase 4 trial update on hyaluronic acid injections for knee osteoarthritis to assess efficacy and outcomes.
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Does Electrocautery Increase Postoperative Pain in Primary Total Knee Arthroplasty [Phase 3]
A Phase 3 clinical trial is examining whether electrocautery increases postoperative pain after primary total knee arthroplasty in patients …
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Treatment of Knee Osteoarthritis With Bone Marrow Aspirate Matrix: Prospective, Randomized Trial [Phase 3]
A Phase 3 prospective, randomized trial evaluating bone marrow aspirate matrix for knee osteoarthritis; not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-01-03Clinical Trial Update: Efficacy of Allogeneic UCMSCs for Treating Large Defects Knee Injury [Phase 2]
Phase 2 trial update on using allogeneic UCMSCs to treat knee osteoarthritis shows completed study.
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: Safety and Efficacy of Sahasthara ME vs Diclofenac ME for Treating Primary Knee Osteoarthritis [Phase 2]
Phase 2 clinical trial comparing Sahasthara ME to Diclofenac ME for primary knee osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee [Phase 2]
Phase 2 trial comparing micronized dHACM to saline for knee osteoarthritis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis [Phase 3]
A Phase 3 trial comparing diacerein to celecoxib in symptomatic knee osteoarthritis assessing symptoms and structural changes; trial complet…
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CLINICAL_TRIALS research · 2023-11-29Clinical Trial Update: In Vivo Kinematics for Subjects With Smith & Nephew Journey II BCS TKA, Journey II CR TKA, Or Journey II XR TKA
Clinical trial update on in vivo kinematics for subjects with specific Journey knee replacements; completed with results posted.
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CLINICAL_TRIALS research · 2023-11-28Clinical Trial Update: Analysis of Competitive Posterior Cruciate Retaining (PCR) and Posterior Stabilized (PS) Total Knee Arthroplasty (TKA)
A completed clinical trial comparing posterior cruciate retaining and posterior stabilized total knee arthroplasty, with results posted in 2…
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CLINICAL_TRIALS trial_result · 2023-11-14Clinical Trial Update: Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients. [Phase 2]
Phase 2 trial evaluating metformin added to ibuprofen for disease activity in knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: iPACK Block With Dexamethasone For Total Knee Replacement [Phase 4]
Phase 4 trial update for iPACK block with dexamethasone in total knee replacement has been terminated.
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Effectiveness of PRP, Conditioned Medium UC-MSCs Secretome and Hyaluronic Acid for the Treatment of Knee Osteoarthritis [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating PRP, conditioned medium UC-MSCs secretome, and hyaluronic acid for knee osteoarthritis has completed.