Kidney Transplant Rejection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Desensitization in Kidney Allograft Using Daratumumab [Phase 1, Phase 2]
Phase 1/2 trial evaluating desensitization in kidney transplantation using daratumumab has been completed.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: An Efficacy and Safety Study of Imlifidase in Treatment of Antibody-Mediated Rejection in Kidney Transplant Patients [Phase 2]
Phase 2 trial updating efficacy and safety of imlifidase for antibody-mediated rejection in kidney transplant patients has completed with re…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Immune Monitoring to Facilitate Belatacept Monotherapy [Phase 4]
A Phase 4 clinical trial update on immune monitoring to facilitate belatacept monotherapy in kidney transplant patients; results posted afte…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients [Phase 4]
Phase 4 clinical trial update on enteric-coated mycophenolate sodium (EC-MPS) assessing efficacy and safety in de novo kidney transplant rec…
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation [Phase 3]
Phase 3 trial comparing FCR001 to standard of care in de novo living donor kidney transplantation was terminated.
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CLINICAL_TRIALS trial_result · 2022-11-09Clinical Trial Update: Belatacept Conversion in Proteinuric Kidney Transplant Recipients [Phase 2]
Phase 2 clinical trial update on converting to belatacept in proteinuric kidney transplant recipients; results posted.
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CLINICAL_TRIALS trial_result · 2022-07-18Clinical Trial Update: Induction of Donor Specific Tolerance in Recipients of Live Donor Kidney Allografts by Donor Stem Cell Infusion [Phase 1, Phase 2]
Phase 1/2 trial investigating donor stem cell infusion to induce donor-specific tolerance in recipients of live donor kidney allografts.
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal Allografts [Phase 4]
Phase 4 trial assessing safety and efficacy of withdrawing calcineurin inhibitors in primary renal allograft recipients after transplantatio…
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CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation (BETTER Trial) [Phase 4]
Phase 4 trial update evaluating belatacept with early steroid withdrawal, rATG, and everolimus in kidney transplant patients with rejection …
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CLINICAL_TRIALS trial_result · 2020-08-10Clinical Trial Update: Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation [Phase 4]
Phase 4 trial update on converting from mycophenolic acid (MPA) to everolimus (Zortress) for GI toxicity after kidney transplantation; study…
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CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: A Multicenter Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediated Rejection in Participants With Kidney Transplant [Phase 3]
Phase 3 trial evaluating Cinryze for acute antibody-mediated rejection in kidney transplant recipients was terminated with results posted in…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Belatacept Compared to Tacrolimus in Deceased Donor Renal Transplant Recipients [Phase 4]
Phase 4 trial comparing belatacept to tacrolimus in deceased donor renal transplant recipients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-11Clinical Trial Update: C1-Inhibitor (INH) for Refractory Antibody Mediated Renal Allograft Rejection [Phase 2]
Phase 2 trial update for C1-Inhibitor (INH) in refractory antibody-mediated rejection after kidney transplant; results have been posted.
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CLINICAL_TRIALS trial_result · 2019-01-03Clinical Trial Update: Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation [Phase 4]
Phase 4 clinical trial comparing antithymocyte globulin with azathioprine to basiliximab with mycophenolate mofetil in living donor kidney t…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Study of Alemtuzumab Versus Anti-thymocyte Globulin to Help Prevent Rejection in Kidney and Pancreas Transplantation [Phase 4]
Phase 4 trial comparing alemtuzumab to anti-thymocyte globulin for prevention of graft rejection in kidney and pancreas transplantation; com…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Anti-Angiotensin II Type 1 Receptor Antibodies and Kidney Transplant Outcomes
Completed clinical trial evaluating anti-AT1 receptor antibodies and kidney transplant outcomes.
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)
This clinical trial update reports completion of a pediatric study investigating how the renin-angiotensin system affects renal transplant i…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: A Study of Belimumab in the Prevention of Kidney Transplant Rejection [Phase 2]
Phase 2 study evaluating belimumab to prevent kidney transplant rejection has completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Non-interventional-study With Tacrolimus Sandoz© Capsules for Prophylaxis of Renal Graft Rejection
This is a completed non-interventional study evaluating tacrolimus Sandoz capsules for prophylaxis of renal graft rejection.
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: Bortezomib in Late Antibody-mediated Kidney Transplant Rejection [Phase 2]
A Phase 2 trial evaluating bortezomib for late antibody-mediated rejection in renal transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Reference Group Trial for The ONE Study [Phase 4]
A Phase 4 reference group trial for The ONE Study sponsored by the University of Regensburg has completed, involving patients with end-stage…
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Impact of Proteasome Inhibition on Anti-Donor HLA Antibody Production After Kidney Transplantation [Phase 2]
A Phase 2 trial assessed proteasome inhibition to reduce anti-donor HLA antibody production after kidney transplantation; results were poste…
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Safety & Tolerability of Berinert® (C1 Inhibitor) Therapy to Prevent Rejection [Phase 1, Phase 2]
Berinert (C1 esterase inhibitor) was studied in Phase 1/2 trials to prevent rejection in kidney transplant recipients. The update reports on…
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection [Phase 2]
Phase 2 study combining kidney transplantation with bone marrow to induce tolerance and prevent rejection; the trial completed with results …
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CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression [Phase 4]
Phase 4 clinical trial evaluating two steroid-free approaches to mycophenolate mofetil–based monotherapy immunosuppression in kidney transpl…