Kidney Failure
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Sign up freeTop drugs studied for this disease
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FDA label_change · 2015-10-16FDA Approved: EXTRANEAL — Supplemental Application (Vantive US Healthcare LLC)
FDA approved a supplemental application for Extraneal (icodextrin) to update its labeling, including the formulation ingredients listed as i…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: The Everolimus-Transplant Exit Strategy Trial (E-TEST) [Phase 3]
Phase 3 trial (E-TEST) investigating everolimus in kidney failure; terminated with posted results in 2015.
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CLINICAL_TRIALS research · 2015-05-19Clinical Trial Update: Thymoglobulin Induction Therapy in Kidney Transplantation (6mg/kg vs 4mg/kg) [Phase 4]
This is a Phase 4 clinical trial update comparing thymoglobulin induction dosing of 6 mg/kg versus 4 mg/kg in kidney transplantation.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery [NA]
Clinical trial investigating minocycline to prevent acute kidney injury after cardiac surgery has completed with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-01-13Clinical Trial Update: 1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy [Phase 4]
Phase 4 trial evaluating desmopressin (DDAVP) to reduce bleeding during ultrasound-guided percutaneous renal biopsy. Results were posted in …
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Comparison of Femoral Versus Jugular Routes for Temporary Hemodialysis in Seriously Ill Patients [NA]
Clinical trial comparing femoral versus jugular venous access for temporary hemodialysis in seriously ill patients; the study is completed.
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CLINICAL_TRIALS trial_result · 2014-11-07Clinical Trial Update: An Investigation of N-acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery [Phase 2]
Phase 2 clinical trial entry reporting a completed study of N-acetylcysteine and fenoldopam as renal protection agents during cardiac surger…
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Reducing Donor Specific Antibody (DSA) Strength in Maintenance Kidney Transplant Recipients (DSA Study) [Phase 4]
Phase 4 clinical trial evaluating strategies to reduce donor-specific antibody strength in maintenance kidney transplant recipients; results…
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FDA approval · 2014-04-23FDA Approved: DELFLEX — Supplemental Application (Fresenius Medical Care de Mexico, S.A. de C.V.)
FDA approved a supplemental application for DELFLEX, a dialysate solution from Fresenius Medical Care de Mexico, S.A. de C.V., updating the …
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CLINICAL_TRIALS research · 2013-11-06Clinical Trial Update: Pilot Study of Contrast-Enhanced Ultrasound of Transplanted Kidney [NA]
A clinical trial update describing a pilot study of contrast-enhanced ultrasound for transplanted kidneys; no phase, status, or results are …
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Erythropoietin (EPO) to Protect Renal Function After Cardiac Surgery [Phase 2]
This document reports the completion of a Phase 2 trial evaluating erythropoietin to protect renal function after cardiac surgery.
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CLINICAL_TRIALS trial_result · 2013-06-18Clinical Trial Update: Tc-99m Renography and Cisplatin-induced Nephrotoxicity
The clinical trial evaluating Tc-99m renography for cisplatin-induced nephrotoxicity has been terminated; no results are provided in the sni…
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: Resistive Index Measurements After Kidney Transplantation
A clinical trial evaluating resistive index measurements after kidney transplantation has completed.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Safety and Efficacy Study of Add On Aliskiren in Patients With Heart Failure and Renal Impairment [Phase 2]
Phase 2 trial evaluating add-on aliskiren in patients with heart failure and kidney failure has been terminated.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: A Pilot Study to Assess the Safety and Efficacy of Alefacept in de Novo Kidney Transplant Recipients [Phase 1]
A Phase 1 pilot study evaluated the safety and efficacy of alefacept in de novo kidney transplant recipients; the trial status is terminated…
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CLINICAL_TRIALS trial_result · 2012-10-22Clinical Trial Update: Angiotensin Converting Enzyme Inhibitors & Contrast Induced Nephropathy in Patients Receiving a Cardiac Catheterization [Phase 2]
Phase 2 clinical trial evaluating the impact of ACE inhibitors on contrast-induced nephropathy in patients undergoing cardiac catheterizatio…
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CLINICAL_TRIALS research · 2012-09-25Clinical Trial Update: Vitamin Metabolism in Kidney Disease
A clinical trial update on vitamin metabolism in kidney disease with an unknown study status.
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CLINICAL_TRIALS trial_result · 2012-08-21Clinical Trial Update: Pharmacokinetics of Tamiflu® (Oseltamivir) in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)and or Continuous Venovenous Hemodialysis (CVVHD) [Phase 4]
Phase 4 pharmacokinetic study evaluating oseltamivir (Tamiflu) in critically ill patients on extracorporeal membrane oxygenation (ECMO) or c…
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CLINICAL_TRIALS trial_result · 2011-11-18Clinical Trial Update: Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial evaluating injections of regulatory T cells (CD4+CD25+FoxP3+ T cells) to prevent organ reje…
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CLINICAL_TRIALS trial_result · 2011-06-02Clinical Trial Update: Validation of Serum Creatinine Dosage and Renal Clearance [Phase 1]
Phase 1 trial updating validation of serum creatinine dosage and renal clearance; the study status is completed.
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CLINICAL_TRIALS trial_result · 2011-05-23Clinical Trial Update: Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients [Phase 4]
Phase 4 study assessing safety and efficacy of converting from a calcineurin inhibitor to sirolimus in renally impaired heart transplant rec…
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CLINICAL_TRIALS trial_result · 2011-03-08Clinical Trial Update: Study Comparing Conversion From Calcineurin Inhibitors to Rapamune Versus Standard Therapy in Established Renal Allograft Recipients [Phase 3]
A Phase 3 trial comparing conversion from calcineurin inhibitors to Rapamune (sirolimus) versus standard therapy in established renal allogr…
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CLINICAL_TRIALS trial_result · 2010-10-13Clinical Trial Update: Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care) [NA]
The IVOIRE high-volume haemofiltration trial in intensive care has completed.
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CLINICAL_TRIALS trial_result · 2010-07-02Clinical Trial Update: Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers [Phase 1]
Phase 1 study comparing absorption of dietary phosphorus when administering FOSRENOL® vs RENVELA® in healthy adult volunteers; completed wit…
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CLINICAL_TRIALS trial_result · 2010-06-23Clinical Trial Update: Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN) [Phase 3]
Phase 3 trial evaluating SEVOREIN, an inhaled sevoflurane, in patients with end-stage kidney disease or acute kidney failure undergoing rena…