Keratoconus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Corneal Elastography and Patient Specific Modeling
A Cleveland Clinic-sponsored clinical trial is evaluating corneal elastography and patient-specific modeling for keratoconus and related cor…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia [Phase 2]
A Phase 2 clinical trial evaluating the safety and effectiveness of the PXL-Platinum 330 System for corneal cross-linking in eyes with corne…
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FDA approval · 2025-10-17FDA Approved: EPIOXA CROSS-LINKING — Original Application (Glaukos Corporation)
The FDA approved the original application for EPIOXA CROSS-LINKING (riboflavin 5-phosphate ophthalmic) by Glaukos Corporation for use in cor…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: One-Year Outcomes After Conventional vs Accelerated Epi-Off Corneal Cross-Linking in Progressive Keratoconus (Observational Cohort)
A clinical trial update summarizing one-year outcomes from an observational cohort comparing conventional epi-off corneal cross-linking vers…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
A clinical trial comparing an AI-driven workflow to a consultant ophthalmologist for diagnosing keratoconus and guiding refractive surgery; …
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Epi-on CuRV and Epi-off aCXL Protocols in the Management of Keratoconus
This update describes completed clinical trial activity for epi-on CuRV and epi-off accelerated corneal collagen crosslinking protocols in m…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Evaluation of Safety and Efficacy of a Bioengineered Corneal Implant for Treatment of Keratoconus [NA]
A completed clinical trial assessing the safety and efficacy of a bioengineered corneal implant for keratoconus.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Collagen Cross-linking in Keratoconus [NA]
Clinical trial update for collagen cross-linking in keratoconus, currently recruiting under NCT03760432.
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Scleral Lens Fitting Using Wide-Field OCT
Clinical trial update describing a study on scleral lens fitting using wide-field OCT for keratoconus with irregular corneal contour; recrui…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: OCT in Diagnosis of Irregular Corneas
A clinical trial update describing an OCT-based diagnostic approach for irregular corneas, including keratoconus and other corneal condition…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Risk Factors and Progression of Keratoconus [NA]
This clinical trial update describes a study on risk factors and progression of keratoconus. It is currently recruiting at University Hospit…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Effect of Corneal and Scleral RGP Lenses on Ocular Health and Visual Quality in Keratoconus [NA]
Clinical trial update indicates a study evaluating corneal and scleral rigid gas-permeable lenses for keratoconus and irregular astigmatism,…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: The K-Map Study, Global Prevalence of KC
The K-Map Study is currently recruiting at University Hospital, Geneva to investigate the global prevalence of keratoconus.
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Comparison of Standard vs. Accelerated Corneal Crosslinking [Phase 2, Phase 3]
A Phase 2/3 trial comparing standard versus accelerated corneal crosslinking for keratoconus and corneal ectasia, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: Efficacy of Corneal Cross-Linking (CXL) in the Treatment of Pediatric Keratoconus [NA]
A completed clinical trial assessed the efficacy of corneal cross-linking for treating pediatric keratoconus.
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CLINICAL_TRIALS other · 2025-05-01Clinical Trial Update: Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus [Phase 3]
Update on a Phase 3 trial evaluating epithelium-on corneal cross-linking for keratoconus; the study in subjects aged 8 to 45 is currently ac…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Use of a Freeze-dried Amniotic Membrane Post Crosslinking in Subjects With Progressive Keratoconus [Phase 3]
Phase 3 clinical trial evaluating the use of a freeze-dried amniotic membrane after corneal crosslinking for progressive keratoconus; curren…
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CLINICAL_TRIALS research · 2025-04-07Clinical Trial Update: Evaluation of Corneal Epithelial Mapping in Diagnosis of Early Keratoconus by Anterior Segment Optical Coherence Tomography
This clinical trial evaluates corneal epithelial mapping using anterior segment optical coherence tomography to aid early diagnosis of kerat…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus [EARLY_Phase 1]
An early Phase 1 trial comparing intracanalicular dexamethasone insert to loteprednol etabonate in keratoconus patients to evaluate safety a…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: McNeel Eye Center Corneal Crosslinking Study [NA]
A clinical trial update for a corneal crosslinking study in keratoconus conducted by McNeel Eye Center; the trial is currently active but no…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Detection of Keratoconus Progression Using Machine Learning
Clinical trial update on detecting progression of keratoconus using machine learning techniques. The study is currently active but not recru…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age with Keratoconus [Phase 3]
Phase 3 trial evaluating epithelium-on corneal cross-linking for keratoconus is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Validation Study on Eye Rubbing Questionnaire in Patients With or Suspected of Having a Keratoconus (KC) [NA]
A completed validation study evaluated an Eye Rubbing Questionnaire for patients with or suspected of having keratoconus. The study aimed to…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution [Phase 1]
Phase 1 trial evaluated the safety and effectiveness of the PXL-Platinum 330 System for corneal cross-linking using riboflavin solution; the…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Theranostic Guided Riboflavin/UV-A Corneal Cross-linking [NA]
Clinical trial NCT05457647 evaluated theranostic guided riboflavin/UV-A corneal cross-linking for keratoconus; the study is completed and re…