Keratoconjunctivitis Sicca
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Tolerability and Efficacy Study of Reinnerva/Lubristil+G vs Vismed [NA]
Completed clinical trial comparing Reinnerva/Lubristil+G versus Vismed for keratoconjunctivitis sicca, evaluating tolerability and efficacy.
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EMA approval · 2026-01-15EMA Authorised: Ikervis (ciclosporin) — Santen Oy
The EMA authorised Ikervis (ciclosporin) for corneal diseases. The marketing authorization holder is Santen Oy, with a decision date of 27 F…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome [Phase 4]
A Phase 4 clinical trial update reports a new therapy for dry eye in patients with Sjögren's syndrome with keratoconjunctivitis, currently r…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Levocarnitine for Dry Eye in Sjogren's Syndrome [Phase 2]
Phase 2 trial of levocarnitine for dry eye in Sjögren's syndrome has completed. The study involved Keratoconjunctivitis Sicca as part of the…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Dose Regimen Study of BRM421 Ophthalmic Solution in Patients With Dry Eye Disease [Phase 2]
Phase 2 dose regimen study of BRM421 Ophthalmic Solution for Dry Eye Disease and Keratoconjunctivitis Sicca is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya [Phase 4]
Phase 4 safety study of the Nasal Guide with Tyrvaya in dry eye and keratoconjunctivitis sicca completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: A Study Evaluating the Safety of the Nasal Pump [Phase 4]
Phase 4 study evaluating the safety of the OC-01 varenicline nasal spray for dry eye disease and keratoconjunctivitis sicca was terminated w…
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EMA approval · 2025-04-24EMA Authorised: Vevizye (ciclosporin) — Laboratoires Théa
The EMA has authorised Vevizye, an ophthalmic ciclosporin product from Laboratoires Théa, for keratoconjunctivitis sicca (dry eye disease).
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK [NA]
The study evaluated goblet cell response and dry eye symptoms after PRK and LASIK, and it has completed.
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: Efficacy and Safety Evaluation of Tavilermide Ophthalmic Solution for the Treatment of Dry Eye [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of tavilermide ophthalmic solution for dry eye disease has completed.
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: A Randomized Study of Smile Exercise for Dry Eye [NA]
A randomized study evaluated smile exercise for dry eye; the trial sponsored by Zhongshan Ophthalmic Center at Sun Yat-sen University has co…
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CLINICAL_TRIALS trial_result · 2023-07-12Clinical Trial Update: Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease [Phase 2]
Phase 2 trial update on pilocarpine ophthalmic topical cream for dry eye disease and keratoconjunctivitis sicca reports safety and efficacy …
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Tavilermide Ophthalmic Solution for the Treatment of Dry Eye [Phase 3]
Phase 3 clinical trial update for tavilermide ophthalmic solution in dry eye conditions; study completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2021-12-10Clinical Trial Update: Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome [Phase 2, Phase 3]
A dose-ranging study of voclosporin ophthalmic solution in dry eye syndrome and keratoconjunctivitis sicca completed Phase 2/Phase 3 with re…
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CLINICAL_TRIALS trial_result · 2021-10-19Clinical Trial Update: Tear Production by Nasal Neurostimulation Compared to Active Control [NA]
Completed clinical trial comparing tear production via nasal neurostimulation to an active control in dry eye conditions; results posted in …
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CLINICAL_TRIALS trial_result · 2021-05-14Clinical Trial Update: Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study [Phase 2]
Phase 2 clinical trial evaluating Pro-ocular for dry eye disease with safety and efficacy outcomes.
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CLINICAL_TRIALS trial_result · 2021-04-02Clinical Trial Update: Safety and Efficacy of KPI-121 in Subjects With DED [Phase 3]
Phase 3 clinical trial update on KPI-121 for keratoconjunctivitis sicca assessing safety and efficacy.
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CLINICAL_TRIALS trial_result · 2021-01-06Clinical Trial Update: Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease [Phase 2]
Phase 2 clinical trial update on KPI-121 for dry eye disease shows safety and efficacy data in subjects with Keratoconjunctivitis Sicca/Dry …
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease [Phase 3]
Phase 3 trial evaluating KPI-121 for safety and efficacy in dry eye disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease [Phase 3]
Phase 3 trial evaluating KPI-121 versus placebo in dry eye disease completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES) [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of an ophthalmic solution (SkQ1) for dry eye syndrome completed with posted result…
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CLINICAL_TRIALS trial_result · 2020-05-27Clinical Trial Update: Safety and Efficacy of Pimecrolimus Ophthalmic Suspension in Patients With Moderate to Severe Keratoconjunctivitis Sicca [Phase 2]
Phase 2 clinical trial updating safety and efficacy of pimecrolimus ophthalmic suspension in moderate to severe keratoconjunctivitis sicca.
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Effects of Dry Eye Treatments on the Ocular Surface [Phase 4]
Phase 4 clinical trial update evaluating the effects of dry eye treatments on the ocular surface.
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FDA label_change · 2019-09-20FDA Approved: CEQUA — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved a supplemental application for Cequa (cyclosporine ophthalmic solution) from Sun Pharmaceutical Industries. The action upda…
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CLINICAL_TRIALS trial_result · 2019-08-30Clinical Trial Update: Lotemax® Gel 0.5% and Restasis 0.05% in Participants With Mild or Moderate Keratoconjunctivitis Sicca (Dry Eye Disease) [Phase 2]
A Phase 2 clinical trial evaluating Lotemax Gel 0.5% and Restasis 0.05% in participants with mild or moderate keratoconjunctivitis sicca (dr…