Kaposi Sarcoma
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma After Systemic Chemotherapy [Phase 2]
Phase II evaluation of low-dose oral etoposide for relapsed or progressed AIDS-related Kaposi's sarcoma after systemic chemotherapy has comp…
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS) [Phase 2]
Phase 2 trial investigating maraviroc for HIV-related Kaposi's sarcoma completed with results posted.
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EMA withdrawal · 2021-01-11EMA Withdrawn: Panretin (alitretinoin) — Eisai GmbH
The EMA has withdrawn Panretin (alitretinoin) from the European market, with Eisai GmbH as the marketing authorization holder, for indicatio…
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CLINICAL_TRIALS trial_result · 2020-07-08Clinical Trial Update: Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions
A completed clinical trial assessing blood vessel density in Kaposi's sarcoma lesions has results posted.
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Phase II Multicentric Study of Pembrolizumab in Classic or Endemic Kaposi's Sarcoma [Phase 2]
Phase II multicentric study evaluating pembrolizumab in classic or endemic Kaposi's sarcoma; current status is unknown.
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FDA approval · 2019-08-12FDA Approved: DOXORUBICIN HYDROCHLORIDE LIPOSOME — Supplemental Application (Baxter Healthcare Company)
FDA approved a supplemental application for doxorubicin hydrochloride liposome submitted by Baxter Healthcare Company.
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CLINICAL_TRIALS trial_result · 2019-02-20Clinical Trial Update: A Study of Selumetinib in Patients With Kaposi's Sarcoma [Phase 1, Phase 2]
A Phase 1/2 trial of Selumetinib for Kaposi's sarcoma in AIDS-related cases has been terminated.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Phase II Multicentric Study of Digoxin Per os in Classic or Endemic Kaposi' s Sarcoma [Phase 2]
A Phase II multicenter trial evaluating oral digoxin for Kaposi's sarcoma, including classic and endemic forms.
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CLINICAL_TRIALS withdrawal · 2017-12-07Clinical Trial Update: Early Phase Evaluation of ABC294640 in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma or Kaposi Sarcoma [Phase 1, Phase 2]
Clinical trial update shows the early-phase study of ABC294640 (opaganib) in refractory/relapsed diffuse large B-cell lymphoma and Kaposi sa…
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CLINICAL_TRIALS trial_result · 2017-07-31Clinical Trial Update: Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma [Phase 3]
Phase 3 trial comparing ART alone or with delayed chemotherapy versus ART with immediate chemotherapy for limited AIDS-related Kaposi's Sarc…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated Cancers
This news update reports on completed pilot studies assessing clinical, laboratory, and epidemiologic aspects in people at high risk for vir…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced Kaposi s Sarcoma [Phase 2]
Phase 2 pilot study evaluating liposomal doxorubicin in combination with bevacizumab, followed by bevacizumab monotherapy, in adults with ad…
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Evaluation of Tc 99m Tilmanocept Localization in Primary Cutaneous Kaposi's Sarcoma and Lymphatic Drainage by SPECT/CT [Phase 2]
Phase 2 results evaluating Tc-99m tilmanocept for localization of primary cutaneous Kaposi's sarcoma and mapping of lymphatic drainage using…
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Treatment With Indinavir and Chemotherapy for Advanced Classical Kaposi's Sarcoma [Phase 2]
Phase 2 trial results evaluate indinavir in combination with chemotherapy for advanced classical Kaposi's Sarcoma; the study status is compl…
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FDA approval · 2016-08-23FDA Approved: PACLITAXEL PACLITAXEL — Original Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved the original application for a generic paclitaxel product, manufactured by Heritage Pharmaceuticals Inc. d/b/a Avet Pharmac…
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CLINICAL_TRIALS trial_result · 2016-07-21Clinical Trial Update: Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating lenalidomide for AIDS-related Kaposi's sarcoma and recurrent Kaposi's sarcoma has been completed with…
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors [EARLY_Phase 1]
Early-phase 1 clinical trial update for nelfinavir in gammaherpesvirus-related tumors, noting termination of the study despite investigation…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: KSHV Infection in Blood Donors From Texas
A completed clinical trial evaluating Kaposi sarcoma–associated herpesvirus (KSHV) infection in Texas blood donors, with related conditions …
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: Valganciclovir in Treating Patients With Classic Non-HIV-Associated Kaposi's Sarcoma [NA]
This clinical-trial update reports on the evaluation of valganciclovir for classic, non-HIV-associated Kaposi's sarcoma; the study is comple…
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FDA approval · 2015-10-09FDA Approved: DOXORUBICIN HYDROCHLORIDE LIPOSOME — Supplemental Application (Baxter Healthcare Company)
FDA approved Baxter's supplemental NDA for doxorubicin hydrochloride liposome.
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Intralesional Bevacizumab for Treating AIDS-associated Kaposi´s Sarcoma of the Larynx, Pharynx and Oral Cavity [Phase 2]
A Phase 2 clinical trial evaluated intralesional bevacizumab for AIDS-associated Kaposi's sarcoma of the larynx, pharynx, and oral cavity, w…
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CLINICAL_TRIALS withdrawal · 2015-07-23Clinical Trial Update: Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi Sarcoma [Phase 2]
Phase 2 trial of the gamma secretase inhibitor PF-03084014 for AIDS-related Kaposi sarcoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Liposomal Daunorubicin in Treating Patients With HIV-Related Kaposi's Sarcoma [Phase 1]
Phase 1 trial of liposomal daunorubicin for HIV-related Kaposi's sarcoma was terminated.
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: A Pilot Study Of the Effects of Highly Active Antiretroviral Therapy on Kaposi's Sarcoma in Zimbabwe [Phase 2, Phase 3]
A pilot Phase 2/3 trial evaluated the effects of highly active antiretroviral therapy on AIDS-related Kaposi's sarcoma in Zimbabwe and has c…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: SU5416 in Treating Patients With AIDS-Related Kaposi's Sarcoma [Phase 2]
A Phase 2 clinical trial evaluating SU5416 for AIDS-related Kaposi's sarcoma has completed, sponsored by the AIDS Malignancy Consortium.