Ischemic Heart Disease
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: Quantitative Cardiac Parametric Mapping [NA]
This entry reports an ongoing clinical trial at the Medical University of South Carolina investigating quantitative cardiac parametric mappi…
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FDA approval · 2025-10-28FDA Approved: TICAGRELOR — Original Application (Dr. Reddys Laboratories Inc)
FDA approved Dr. Reddy's Laboratories' original application for ticagrelor as a generic version of the antiplatelet drug, expanding access t…
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FDA approval · 2025-10-28FDA Approved: TICAGRELOR — Original Application (Apotex Corp.)
FDA approved Apotex Corp.'s original application for a ticagrelor generic.
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FDA approval · 2025-10-28FDA Approved: TICAGRELOR — Original Application (Radha Pharmaceuticals INC)
FDA approves Radha Pharmaceuticals INC's original ANDA for Ticagrelor, a generic antiplatelet medication.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Coronary CT Angiogram - Prognostic Value of Adverse Plaque Features in Guiding Treatment (CT-PLAQUE)
The CT-PLAQUE trial investigates whether adverse plaque features seen on coronary CT angiography can predict prognosis and guide treatment, …
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE) [NA]
The V-EDUCATE trial evaluating video education to improve blood pressure control in patients with ischemic heart disease and hypertension ha…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Safety Study of Gene Therapy for Ischemic Heart Disease in Korea [Phase 1, Phase 2]
This document reports safety results from a Phase 1/2 gene therapy trial (VM202) for ischemic heart disease in Korea. Results were posted on…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Impact of a Technology Platform Based on Enhanced Recovery After(ERAS) Surgery on Length of Stay After Coronary Artery Bypass Grafting: Timely Project [NA]
A clinical trial is underway to evaluate a technology platform intended to support Enhanced Recovery After Surgery (ERAS) and reduce length …
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass
Ain Shams University‑led clinical trial investigates whether the arterial-to-central CO2 gap predicts outcomes after cardiopulmonary bypass;…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Imaging and Treatment Planning for Cardiac Radioablation [NA]
This clinical trial update describes imaging and treatment planning approaches for cardiac radioablation to treat ventricular tachycardia, w…
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CLINICAL_TRIALS withdrawal · 2025-09-25Clinical Trial Update: Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea [Phase 2]
A Phase 2 safety and efficacy trial of a gene therapy for acute myocardial infarction in Korea has been withdrawn.
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG [Phase 2]
Rohto Pharmaceutical is conducting a Phase 2 exploratory trial of ADR-002K in heart failure patients with ischemic heart disease undergoing …
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Stress CMR With Vasodilators to Predict Long-Term Mortality
The update reports a trial investigating stress CMR with vasodilators to predict long-term mortality in ischemic heart disease; the study is…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: A Study of iPS Cell-derived Cardiomyocyte Spheroids (HS-001) in Patients With Heart Failure (LAPiS Study) [Phase 1, Phase 2]
The LAPiS study is a Phase 1/2 clinical trial evaluating iPS cell-derived cardiomyocyte spheroids (HS-001) for heart failure and ischemic he…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Verona Coronary Physiology Interventional Registry
Verona Coronary Physiology Interventional Registry is listed as active but not recruiting, a registry study related to coronary artery disea…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Impact of Gut Microbiota on Clinical Outcomes and Left Ventricular Remodeling After Primary Percutaneous Coronary Intervention
This clinical trial investigates how gut microbiota influences clinical outcomes and left ventricular remodeling after primary percutaneous …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes [NA]
This clinical trial update describes a partially randomized patient-preference study comparing minithoracotomy versus sternotomy for multive…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: "The Effect of The Combination Therapy of Statin and SGLT2i in The Treatment of Ischemic Heart Disease"
This clinical trial update reports a study evaluating the combination of a statin and an SGLT2 inhibitor for ischemic heart disease and is c…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Effects of Yangxinshi Pills on the Exercise Tolerance Compared With Trimetazidine in Patients After PCI [Phase 4]
Phase 4 clinical trial comparing Yangxinshi Pills with Trimetazidine in patients after percutaneous coronary intervention has completed, eva…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: A Clinical Trial on No-touch Vein Graft (NT-graft) in Coronary Surgery [NA]
A clinical trial evaluating the No-touch Vein Graft technique in coronary surgery has completed.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: MRI of Myocardial Infarction
A clinical trial at the University of Pennsylvania evaluating MRI in myocardial infarction has completed. The provided snippet does not incl…
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CLINICAL_TRIALS withdrawal · 2025-09-05Clinical Trial Update: Addressing Social Vulnerabilities in Cardiovascular Disease [NA]
A UCSF-sponsored clinical trial addressing social vulnerabilities in cardiovascular disease has been withdrawn. The study targeted congestiv…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Observational BELgian Registry of Implanted EV-ICD to Evaluate Parameters and Complications of the New Device in Real World Settings
An observational Belgian registry assessing a newly implanted EV-ICD device's performance and complications in real-world patients; the stud…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination [NA]
The trial update from Weill Medical College of Cornell University reports that results for a study on improving how older adults at risk for…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD) [Phase 1, Phase 2]
A Phase 1/2 clinical trial of allogeneic mesenchymal stem cell infusion therapy for endothelial dysfunction in diabetic patients with sympto…