Irreversible Pulpitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Effect of Cryotherapy on Postoperative Pain for Pulpotomy [EARLY_Phase 1]
A Phase 1 clinical trial investigates the effect of cryotherapy on postoperative pain after pulpotomy in irreversible pulpitis; the study is…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis [NA]
This clinical trial update shows that recruitment is ongoing for a study comparing pulpotomy and root canal treatment in teeth with symptoma…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis [NA]
A completed clinical trial comparing Vital Pulp Therapy with Root Canal Treatment for mature teeth with irreversible pulpitis, assessing com…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full Pulpotomy in Symptomatic Permanent Mature Molars [NA]
This clinical trial update examines whether pre-operative dental condition and AI-assisted diagnosis can predict the success of full pulpoto…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating two different sealer materials for root canal obturation in teeth with symptomatic irreversible pulpitis…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars [NA]
Update on a clinical trial evaluating lesion sterilization tissue repair versus conventional pulpectomy in primary molars; the study is curr…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Clinical and Radiographic Outcomes of Rotary Instrumentation in Primary Molars [NA]
A clinical trial update describing rotary instrumentation in primary molars for pulpectomy in irreversible pulpitis, currently NOT_YET_RECRU…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Effect of Menstrual Phase on the Anesthetic Efficacy [NA]
A clinical trial studying whether menstrual phase affects the efficacy of anesthesia in irreversible pulpitis. The study is currently recrui…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Neurokinin A and Matrix Metalloproteinase 9 Levels in Gingival Crevicular Fluid Samples of Teeth With Symptomatic Irreversible Pulpitis With Symptomatic Apical Periodontitis
This clinical trial entry describes a study measuring neurokinin A and matrix metalloproteinase-9 levels in gingival crevicular fluid from t…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis [NA]
A clinical trial is evaluating laser-assisted pulpotomy versus conventional pulpotomy in mature molar teeth with irreversible pulpitis and i…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Can Pretreatment With Analgesics Reduce Postendodontic Pain? [NA]
A completed clinical trial evaluating whether pretreatment with analgesics can reduce postendodontic pain in irreversible pulpitis.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Effect of Probiotics, Double Antibiotic Paste, and Calcium Hydroxide on Postoperative Pain in Irreversible Pulpitis: A Randomized Trial [NA]
Completed randomized trial evaluating the effects of probiotics, double antibiotic paste, and calcium hydroxide on postoperative pain in irr…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Comparison of IL-8, FGF-1 and VEGF Levels in Pulpal Tissue, GCF and Dentinal Fluid Samples of Healthy, Reversible and Irreversible Pulpitis Diagnosed Teeth
A completed clinical trial comparing levels of IL-8, FGF-1 and VEGF in pulpal tissue, gingival crevicular fluid, and dentinal fluid across h…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Cytokines as Diagnostic Markers of Pulpal Inflammation and Their Impact on the Outcome of Vital Pulp Therapy [NA]
A completed clinical trial evaluating cytokines as diagnostic markers of pulpal inflammation and their impact on the outcome of vital pulp t…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples
A clinical trial from Kırıkkale University is evaluating levels of Aquaporin-4, -5, -9 and IL-8 in gingival crevicular fluid, dentin fluid, …
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain in Maxillary Premolars With Acute Irreversible Pulpitis [NA]
This clinical trial by Al-Azhar University is recruiting to assess how different instrumentation kinematics during endodontic procedures aff…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: The Effect of Dexamethasone in Full Pulpotomy on Postoperative Pain in Permanent Molars [NA]
Completed clinical trial evaluating whether dexamethasone reduces postoperative pain after full pulpotomy in permanent molars.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Evaluation of the Effects of Different Irrigation Solutions and Activation Methods on Postoperative Pain and Quality of Life in Root Canal Treatment [NA]
This clinical trial evaluates how different irrigation solutions and activation methods affect postoperative pain and quality of life after …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy
This clinical trial investigates how genetic polymorphisms influence the success of vital pulp therapy in dental patients.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Comparison of Pain Between Supraperiosteal Injection of Dexamethasone Versus Placebo on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis [NA]
The study compares supraperiosteal dexamethasone injection versus placebo for postoperative pain in teeth with symptomatic irreversible pulp…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp [NA]
This clinical trial entry registers a study comparing pulpotomy versus pulpectomy in primary molars with irreversible pulpitis or pulp necro…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods [NA]
A clinical trial is evaluating post-operative pain after different root canal irrigant activation methods in irreversibly inflamed pulpit co…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Outcomes of Full Pulpotomy Treatment in Teeth With Symptoms of Irreversible Pulpitis [Phase 4]
Phase 4 clinical trial update evaluating outcomes of full pulpotomy treatment for irreversible pulpitis.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness [Phase 3]
A Phase 3 clinical trial evaluating whether combining oral premedications improves the effectiveness of the inferior alveolar nerve block fo…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Complete Pulpotomy and Root Canal Treatment Patients With Irreversible Pulpitis With Type 2 Diabetes Mellitus [NA]
Clinical trial investigating complete pulpotomy and root canal treatment in patients with irreversible pulpitis and type 2 diabetes mellitus…