Intracranial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2016-12-23Clinical Trial Update: Non-invasive Intracranial Pressure (ICP) Monitoring in Pediatric Patients [NA]
A pediatric trial evaluating non-invasive intracranial pressure monitoring for intracranial hypertension has been withdrawn.
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CLINICAL_TRIALS research · 2016-12-14Clinical Trial Update: Ocular Point of Care Ultrasound (POCUS) to Detect Optic Disc Swelling in Comparison to Ophthalmologic Examination [NA]
This clinical trial investigates the use of ocular point-of-care ultrasound to detect optic disc swelling, comparing it to standard ophthalm…
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CLINICAL_TRIALS withdrawal · 2016-11-10Clinical Trial Update: Dexmedetomidine on Optic Nerve Sheath Diameter [NA]
A clinical trial evaluating dexmedetomidine on optic nerve sheath diameter for intracranial hypertension has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Prospective Evaluation of the Non-invasive ICP HeadSense Monitor in TBI Patients Undergoing Invasive ICP Monitoring [NA]
A completed prospective trial evaluating the HeadSense non-invasive intracranial pressure monitor in patients with traumatic brain injury un…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Development and Evaluation of the ICP Waveform Tracing Capabilities and Safety of HS-1000 Device [NA]
A completed clinical trial evaluating the HS-1000 device for intracranial pressure waveform tracing, focusing on safety and capabilities in …
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: An Evaluation of Non-invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an External Ventricular Drainage (EVD) Device [NA]
This entry provides an update on a clinical trial evaluating non-invasive intracranial pressure monitoring in patients undergoing invasive I…
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CLINICAL_TRIALS research · 2015-08-17Clinical Trial Update: Impact of Cardiac Blood Flow on Cerebral Blood Flow in Patients With Severe Traumatic Brain Injury [Phase 2]
Phase 2 clinical trial examining whether cardiac blood flow influences cerebral blood flow in patients with severe traumatic brain injury an…
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FDA approval · 2015-07-15FDA Approved: OSMITROL — Supplemental Application (Baxter Healthcare Company)
FDA approved a supplemental application for Osmitrol (mannitol) from Baxter Healthcare Company, authorizing changes to the product's labelin…
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CLINICAL_TRIALS research · 2015-02-11Clinical Trial Update: TCD Detection of Ophthalmic Artery Blood Flow Velocity Prediction Feasibility Study of Intracranial Pressure
A feasibility study update evaluating transcranial Doppler detection of ophthalmic artery blood flow velocity to predict intracranial pressu…
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CLINICAL_TRIALS trial_result · 2015-01-28Clinical Trial Update: The Effect of Stellate Ganglion Block on Intracranial Pressure Predicted by Ultrasonographic Assessment of Optic Nerve Sheath Diameter
A completed clinical trial evaluating whether stellate ganglion block can affect intracranial pressure, as predicted by ultrasonographic ass…
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CLINICAL_TRIALS research · 2014-11-06Clinical Trial Update: Comparison of Two Different Medications Used to Treat Elevated Intracranial Pressure [Phase 1]
A Phase 1 trial update compares two medications intended to treat elevated intracranial pressure, sponsored by Thomas Jefferson University. …
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Hypothermia to Prevent High Intracranial Pressure in Patients With Acute Liver Failure [NA]
A completed clinical trial evaluated whether hypothermia could prevent elevated intracranial pressure in patients with acute liver failure.
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CLINICAL_TRIALS research · 2014-07-28Clinical Trial Update: Clinical Value of Noninvasive Intracranial Pressure Measurement [Phase 2, Phase 3]
This document provides an update on a clinical trial evaluating noninvasive intracranial pressure measurement for intracranial hypertension,…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Automated Chest Physiotherapy to Improve Outcomes in Neuro
A completed clinical trial from Duke University evaluating automated chest physiotherapy to improve outcomes in patients with brain injury a…
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit [Phase 4]
Phase 4 clinical trial update for NIMI-NICU, a non-invasive intracranial pressure monitoring system, with completed status.
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CLINICAL_TRIALS withdrawal · 2014-04-14Clinical Trial Update: The Hemodynamic Effects During Sustained Low-efficiency Dialysis Versus Continuous Veno-venous Hemofiltration for Patients With Intracranial Hypertension in a Cross Over Study
A clinical trial comparing sustained low-efficiency dialysis versus continuous veno-venous hemofiltration in patients with intracranial hype…
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: 3-D Transcranial Ultrasound Analysis Study [NA]
The 3-D Transcranial Ultrasound Analysis Study sponsored by Duke University has completed its trial status for conditions including stroke a…
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Hypertonic Saline vs. Mannitol for Elevated Intercranial Pressure [Phase 3]
A Phase 3 trial comparing hypertonic saline to mannitol for elevated intracranial pressure in traumatic brain injury has been terminated.
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CLINICAL_TRIALS research · 2013-02-25Clinical Trial Update: Assessment of Autonomic Neuronal Changes During Moderate Rise of Intracranial Pressure in Human [NA]
A completed clinical trial assessing autonomic neuronal changes during a moderate rise in intracranial pressure. The update does not indicat…
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CLINICAL_TRIALS trial_result · 2012-11-08Clinical Trial Update: Comparison of 2 Doses of Mannitol on Post Traumatic Intracranial Hypertension and Cerebral Monitoring [Phase 4]
Phase 4 clinical trial comparing two doses of mannitol for post-traumatic intracranial hypertension has been terminated; the update notes th…
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Cerebral Hemodynamic Effects of Hypertonic Solutions in Severely Head-Injured Patients
This clinical trial update reports on a terminated study evaluating the cerebral hemodynamic effects of hypertonic solutions in patients wit…
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CLINICAL_TRIALS trial_result · 2011-05-05Clinical Trial Update: Comparison of Two Doses of Mannitol on Brain Relaxation During Supratentorial Craniotomy [NA]
This completed clinical trial compares two doses of Mannitol for brain relaxation during supratentorial craniotomy. The study was sponsored …
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CLINICAL_TRIALS trial_result · 2010-06-23Clinical Trial Update: Sodium-Lactate and Traumatic Brain Injury [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating sodium lactate for severe traumatic brain injury with intracranial hypertension has been terminated.
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CLINICAL_TRIALS research · 2010-05-24Clinical Trial Update: Evaluation the Intracranial Volume Pressure Response in Increased Intracranial Pressure
This clinical trial update describes a study evaluating intracranial volume pressure response in patients with brain injury and intracranial…
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CLINICAL_TRIALS trial_result · 2009-12-23Clinical Trial Update: Impact of Ventricular Catheter Used With Antimicrobial Agents on Patients With a Ventricular Catheter [Phase 3]
Phase 3 trial evaluating the impact of using a ventricular catheter with antimicrobial agents in patients requiring a ventricular catheter f…