Indolent Non-hodgkin Lymphoma
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CLINICAL_TRIALS trial_result · 2021-08-12Clinical Trial Update: Efficacy and Safety Study of Tenalisib (RP6530), a Novel PI3K δ/γ Dual Inhibitor in Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (iNHL) [Phase 2]
Phase 2 study of Tenalisib (RP6530), a dual PI3K δ/γ inhibitor, in relapsed/refractory indolent non-Hodgkin's lymphoma; study completed with…
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Combination of PCI-32765 With Obinutuzumab in Untreated Follicular Lymphoma [Phase 2]
Phase 2 trial evaluating PCI-32765 (acalabrutinib) in combination with obinutuzumab for untreated indolent non-Hodgkin lymphoma.
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CLINICAL_TRIALS trial_result · 2021-03-19Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Idelalisib in Japanese Participants With Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphomas (iNHL) or Chronic Lymphocytic Leukemia (CLL) [Phase 1]
Phase 1 trial in Japanese participants assessing safety, tolerability, and pharmacokinetics of idelalisib in relapsed or refractory indolent…
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CLINICAL_TRIALS trial_result · 2021-03-18Clinical Trial Update: Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 study evaluating idelalisib in combination with various chemotherapeutic, immunomodulatory agents, and anti-CD20 antibody in relapse…
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: A Phase 2 Clinical Trial of Rituxan and B-Glucan PGG in Relapsed Indolent Non-Hodgkin Lymphoma [Phase 2]
Phase 2 trial evaluating Rituxan (rituximab) with beta-glucan PGG in relapsed indolent B-cell non-Hodgkin lymphoma has completed, with resul…
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CLINICAL_TRIALS trial_result · 2020-11-23Clinical Trial Update: Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell Malignancies [Phase 1]
Phase 1 trial evaluating anti-CD20 radioimmunotherapy before chemotherapy and stem cell transplant in high-risk B-cell malignancies; trial s…
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Study of Vorinostat (MK-0683) With Follicular Lymphoma (FL), Other Indolent B-cell Non-Hodgkin's Lymphoma (B-NHL), or Mantle Cell Lymphoma (MCL) Participants (MK-0683-103) [Phase 2]
Phase 2 study MK-0683-103 evaluated vorinostat in follicular lymphoma, other indolent B-cell non-Hodgkin lymphomas, and mantle cell lymphoma…
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CLINICAL_TRIALS trial_result · 2020-06-02Clinical Trial Update: Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic Malignancies [Phase 2]
Phase 2 trial of Entospletinib plus Idelalisib in adults with relapsed or refractory hematologic malignancies was terminated; results posted…
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CLINICAL_TRIALS trial_result · 2020-03-27Clinical Trial Update: Ofatumumab Bendamustine Combination Compared With Bendamustine Monotherapy in Indolent B-cell NHL Unresponsive to Rituxtherapy [Phase 3]
Phase 3 trial comparing ofatumumab-bendamustine versus bendamustine alone in rituximab-refractory indolent B-cell non-Hodgkin lymphoma was t…
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: A Study of Duvelisib in Participants With Refractory Indolent Non-Hodgkin Lymphoma [Phase 2]
Phase 2 clinical trial of duvelisib in participants with refractory indolent non-Hodgkin lymphoma has completed and results were posted in 2…
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Bortezomib, Rituximab, Cyclophosphamide, and Prednisone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma [Phase 1, Phase 2]
Phase 1/2 study evaluating bortezomib, rituximab, cyclophosphamide, and prednisone in relapsed or refractory indolent non-Hodgkin's lymphoma…
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CLINICAL_TRIALS trial_result · 2018-09-04Clinical Trial Update: A Trial to Investigate the Efficacy of Bendamustine in Patients With Indolent Non-Hodgkin's Lymphoma (NHL) Refractory to Rituximab. [Phase 3]
Phase 3 trial evaluating bendamustine in indolent non-Hodgkin's lymphoma refractory to rituximab; study terminated.
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin Lymphoma [Phase 2]
Phase 2 clinical trial investigating vorinostat and rituximab in indolent non-Hodgkin lymphoma completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma [Phase 2]
This Phase 2 trial evaluated the combination of vorinostat, cladribine, and rituximab in patients with mantle cell lymphoma, relapsed chroni…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Study Evaluating Inotuzumab Ozogamicin (CMC-544) In Indolent Non-Hodgkins Lymphoma [Phase 2]
Phase 2 study evaluating inotuzumab ozogamicin (CMC-544) in indolent non-Hodgkin lymphoma has completed and results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: A Phase II Study for Patients With Indolent Non-follicular Non-Hodgkin's Lymphoma [Phase 2]
A Phase II trial for indolent non-follicular non-Hodgkin's lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Efficacy and Safety of Idelalisib (GS-1101) in Combination With Bendamustine and Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas [Phase 3]
Phase 3 trial evaluating idelalisib with bendamustine and rituximab in previously treated indolent non-Hodgkin lymphomas was terminated; res…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Efficacy and Safety of Idelalisib (GS-1101) in Combination With Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas [Phase 3]
Phase 3 trial evaluating idelalisib (GS-1101) with rituximab in previously treated indolent non-Hodgkin lymphoma was terminated with posted …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: High Dose Rituximab for Initial Treatment of Indolent B-Cell Lymphomas [Phase 2]
Phase 2 results are reported for high-dose rituximab as initial therapy for indolent non-Hodgkin lymphoma. The trial has completed, with res…
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CLINICAL_TRIALS trial_result · 2017-05-05Clinical Trial Update: Phase II Randomized Trial Comparing GA101 and Rituximab in Untreated Low Tumor Burden Indolent Non-Hodgkin's Lymphoma [Phase 2]
A Phase II randomized trial compared GA101 (obinutuzumab) to Rituximab in untreated low tumor burden indolent non-Hodgkin lymphoma; results …
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Phase II Study of Vismodegib in Patients With Refractory or Relapsed B-cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
Phase II study of vismodegib in refractory or relapsed B-cell lymphoma or chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: Safety and Efficacy Study of Idelalisib (GS-1101, CAL-101) in Patients With Previously Treated Low-grade Lymphoma [Phase 1, Phase 2]
Clinical trial update for idelalisib (GS-1101) in previously treated indolent non-Hodgkin's lymphoma, including follicular lymphoma, reporti…
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Bendamustine Compared With Bendamustine+Obinutuzumab (GA101) in Participants With Rituximab-Refractory, Indolent Non-Hodgkin's Lymphoma (GADOLIN) [Phase 3]
Phase 3 trial comparing bendamustine alone to bendamustine plus obinutuzumab in rituximab-refractory indolent non-Hodgkin's lymphoma complet…
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CLINICAL_TRIALS trial_result · 2016-10-06Clinical Trial Update: A Study of TRU-016 in Combination With Rituximab and Bendamustine in Subjects With Relapsed Indolent Lymphoma [Phase 1]
Phase 1 study evaluating TRU-016 in combination with Rituximab and Bendamustine in relapsed indolent B-cell lymphoma; results posted in 2016…