Immune Thrombocytopenia
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Biological Bank for the Patients Followed in a Constitutive Reference Center for Autoimmune Cytopenia
This study update describes the establishment of a biological bank and current recruitment for patients with autoimmune cytopenias at a refe…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders [Phase 2]
A Phase 2 basket study evaluating the efficacy, safety and pharmacokinetics of iptacopan (LNP023) in autoimmune benign hematological disorde…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP [Phase 2]
This update reports results from a Phase 2 study evaluating eltrombopag in combination with a short course of dexamethasone for newly diagno…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Phase III Study on HMPL-523 for Treatment of ITP [Phase 3]
Phase III study of HMPL-523 for Primary Immune Thrombocytopenia is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP). [Phase 3]
A Phase 3 trial evaluating efgartigimod in adults with immune thrombocytopenia has completed and posted results.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: An Open, Exploratory Clinical Study of CM336 in the Treatment of Immune Thrombocytopenia [Phase 2]
Open, exploratory Phase 2 clinical trial evaluating CM336 for treatment of immune thrombocytopenia is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: A Clinical Study on the Efficacy and Safety of Herombopag in the Treatment of Senile Primary ITP [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of Herombopag for senile primary immune thrombocytopenia and is currently rec…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: A Prospective, One-arm and Open Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia [Phase 2]
A Phase 2, prospective, single-arm, open-label study of CM313 in immune thrombocytopenia has completed.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: A Prospective, One-arm and Open Clinical Study of Zanubrutinib in the Treatment of Immune Thrombocytopenia [Phase 2]
A Phase 2, single-arm, open-label trial to evaluate zanubrutinib for immune thrombocytopenia is recruiting in China. The study is sponsored …
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies [Phase 2]
Phase 2 clinical trial update describing avatrombopag for adults with immune thrombocytopenia with autoantibodies, currently recruiting.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Avatrombopag in the Treatment of Pediatric Immune Thrombocytopenia [Phase 2]
Phase 2 clinical trial evaluating avatrombopag for treatment of pediatric immune thrombocytopenia. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: TPO-RA in Primary Immune Thrombocytopenia (ITP) in Patients Older Than 14 Years [NA]
Clinical trial update for a thrombopoietin receptor agonist (TPO-RA) in immune thrombocytopenia in patients aged 14 years and older; the stu…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: A Prospective, One-arm and Open Clinical Study of Obinutuzumab in the Treatment of Pediatric Primary Immune Thrombocytopenia (ITP) [Phase 2]
This is a Phase 2, prospective, single-arm trial evaluating obinutuzumab for pediatric immune thrombocytopenia, currently recruiting in Chin…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Evaluation of Immune Status Before and After Splenectomy in Immune Thrombocytopenia Patients
This ClinicalTrials.gov entry notes a study evaluating immune status before and after splenectomy in patients with immune thrombocytopenia. …
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Study of Human Umbilical Cord-derived Mesenchymal Stem Cells for Treatment of Refractory Immune Thrombocytopenia [NA]
The study investigating human umbilical cord-derived mesenchymal stem cells for refractory immune thrombocytopenia has been completed.
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: A Prospective, One-arm and Open Clinical Study of Obinutuzumab in the Treatment of Immune Thrombocytopenia [Phase 2]
Phase 2 prospective, one-arm open trial evaluating obinutuzumab for immune thrombocytopenia, currently recruiting in China.
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Role of Eltrombopag as First Line Therapy in Primary Immune Thrombocytopenia. [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating eltrombopag as first-line therapy for Primary Immune Thrombocytopenia; the study is currently recru…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Evaluation of Avatrombopag for the Treatment of Thrombocytopenia in Japanese Adults With Chronic ITP [Phase 3]
A Phase 3 trial evaluating avatrombopag for chronic immune thrombocytopenia in Japanese adults has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Evaluation of Avatrombopag for the Treatment of Thrombocytopenia in Japanese Adults With Chronic ITP [Phase 3]
Phase 3 trial evaluating avatrombopag for chronic immune thrombocytopenia in Japanese adults has completed with results posted.
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CLINICAL_TRIALS other · 2025-02-10Clinical Trial Update: Cognitive Dysfunction in Chronic and Persistent Immune Thrombocytopenia
This registry entry describes a study investigating cognitive dysfunction in people with immune thrombocytopenia that is currently recruitin…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Mesenchymal Stem Cells in the Treatment of Refractory Primary Immune Thrombocytopenia [NA]
A clinical trial is evaluating mesenchymal stem cell therapy for patients with refractory primary immune thrombocytopenia. The study is curr…
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FDA approval · 2025-02-04FDA Approved: TAVALISSE — Supplemental Application (Rigel Pharmaceuticals, Inc.)
The FDA approved a supplemental application for TAVALISSE (fostamatinib) submitted by Rigel Pharmaceuticals, Inc.
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Ripertamab Plus Eltrombopag vs. Eltrombopag in ITP Patients Post-Steroid Failure [NA]
Clinical trial comparing Ripertamab plus eltrombopag versus eltrombopag alone in patients with immune thrombocytopenia after failure of ster…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: BCMA-CD19 CCAR T Cell Treatment of Refractory Immune Thrombocytopenia Associated with Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial is evaluating BCMA-CD19 CCAR T cell therapy for refractory immune thrombocytopenia associated with autoimmune disea…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Study on Glucocorticoid Combined With Gamma Globulin and Ropristine N01 in Treatment of Initial Severe ITP [Phase 2]
Phase 2 study evaluating the combination of glucocorticoids, gamma globulin, and Ropristine N01 for initial severe primary immune thrombocyt…