Iga Nephropathy
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Sign up freeTop drugs studied for this disease
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FDA approval · 2021-12-15FDA Approved: TARPEYO — Original Application (Calliditas Therapeutics AB)
FDA approved Tarpeyo (budesonide) from Calliditas Therapeutics AB through an original application for the treatment of IgA nephropathy. This…
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CLINICAL_TRIALS trial_result · 2021-10-08Clinical Trial Update: Trial of Plasma Exchange for Severe Crescentic IgA Nephropathy [Phase 2, Phase 3]
Clinical trial update for plasma exchange in severe crescentic IgA nephropathy indicates termination after Phase 2/3.
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CLINICAL_TRIALS trial_result · 2021-06-04Clinical Trial Update: Steroids Therapy in IgA Nephropathy With Crescents [Phase 3]
Phase 3 trial update investigating steroid therapy for IgA nephropathy with crescents.
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Efficacy and Safety of Atacicept in IgA Nephropathy [Phase 2]
Phase 2 trial of atacicept in IgA nephropathy was terminated with posted results in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment [Phase 4]
Phase 4 trial updating prevention of recurrence after kidney transplantation in IgA nephropathy comparing ATG-F versus Basiliximab induction…
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: Leflunomide Plus Low Dose Corticosteroid in Immunoglobulin A (IgA) Nephropathy With Renal Insufficiency [Phase 4]
A Phase 4 clinical trial evaluating leflunomide plus low-dose corticosteroid in IgA nephropathy with renal insufficiency.
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy (IgAN) [Phase 3]
Phase 3 trial update on mycophenolate mofetil (MMF) for IgA nephropathy has completed.
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CLINICAL_TRIALS trial_result · 2019-06-27Clinical Trial Update: Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) Nephropathy [Phase 2]
Phase 2 clinical trial update for fostamatinib in IgA nephropathy reports safety and efficacy data.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Pilot Study of ACTH in the Treatment of Immunoglobulin A (IgA) Nephropathy at High Risk of Progression [Phase 3]
Phase 3 pilot study results for ACTH in progressive IgA nephropathy with high risk of progression have been completed and results posted.
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CLINICAL_TRIALS research · 2019-02-08Clinical Trial Update: Effect of Immunosuppression in IgA Nephropathy [Phase 4]
A Phase 4 clinical trial from Yonsei University is evaluating the effects of immunosuppression in biopsy-proven IgA nephropathy, with the cu…
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: Pilot Study of Velcade® in IgA Nephropathy [Phase 4]
Pilot Phase 4 study of Velcade in IgA nephropathy has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-10-10Clinical Trial Update: Efficacy and Safety of Losartan in Children With Ig A Nephropathy [Phase 3]
Phase 3 trial update evaluating efficacy and safety of losartan in children with IgA nephropathy (IgA glomerulonephritis) completed.
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: Fecal Microbiota Transplantation for Refractory IgA Nephropathy [Phase 2]
Phase 2 clinical trial update on fecal microbiota transplantation for refractory IgA nephropathy.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: A Study of Hydroxychloroquine Sulfate for Reduction of Proteinuria in Patients With IgA Nephropathy [Phase 2]
Phase 2 trial evaluating hydroxychloroquine sulfate for reducing proteinuria in IgA nephropathy has been completed.
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy [Phase 4]
A Phase 4 trial update suggests hydroxychloroquine sulfate may alleviate persistent proteinuria in primary IgA nephropathy, though status is…
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: BRIGHT-SC: Blisibimod Response in IgA Nephropathy Following At-Home Treatment by Subcutaneous Administration [Phase 2, Phase 3]
Phase 2/3 trial update on blisibimod for IgA nephropathy, including at-home subcutaneous administration.
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Extended Follow-up of Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy [Phase 4]
This document provides extended follow-up data from a Phase 4 study of prednisone plus cyclophosphamide in patients with advanced IgA nephro…
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CLINICAL_TRIALS research · 2017-07-14Clinical Trial Update: Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy [Phase 4]
This clinical trial update describes a Phase 4 study evaluating prednisone plus cyclophosphamide for advanced-stage IgA nephropathy. The sta…
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CLINICAL_TRIALS research · 2017-05-23Clinical Trial Update: Tonsillectomy and Primitive IgA Nephropathy in Children: Strasbourg Cohort and Assessment Practices in Inter North East Region
This ClinicalTrials.gov update describes a pediatric Strasbourg cohort investigating the relationship between tonsillectomy and primary IgA …
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CLINICAL_TRIALS withdrawal · 2017-04-05Clinical Trial Update: Acthar on Proteinuria in IgA Nephropathy Patients [Phase 4]
A Phase 4 trial evaluating Acthar for proteinuria in IgA nephropathy has been withdrawn.
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CLINICAL_TRIALS research · 2017-01-25Clinical Trial Update: Multicenter Study Evaluating the Performance of the Assay of Anti-hinge Region Antibodies in the Diagnosis of Progressive Forms of IgA Nephropathy [NA]
A multicenter study evaluating the performance of an anti-hinge region antibody assay for diagnosing progressive IgA nephropathy. The trial …
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Efficacy and Safety of a Combination of Mycophenolate Mofetil and Corticosteroid in Advanced IgA Nephropathy [Phase 4]
This document reports an update on a Phase 4 trial evaluating the combination of mycophenolate mofetil and corticosteroid for advanced IgA n…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Rituximab in Progressive Immunoglobulin A (IgA) Nephropathy [Phase 4]
Phase 4 study evaluating rituximab in progressive IgA nephropathy completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Additive Renoprotective Effects of Oral Calcitriol in IgA Nephropathy Patients Taking Renin-Angiotensin System Blockers [NA]
A completed clinical trial assessed whether adding oral calcitriol provides additional renoprotective effects for patients with IgA nephropa…
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CLINICAL_TRIALS research · 2016-08-22Clinical Trial Update: IgA Nephropathy, Lymphocyte Homing and IgA Class Switch [NA]
This entry reports on a completed clinical trial investigating IgA nephropathy with a focus on lymphocyte homing and IgA class switch proces…