Idiopathic Thrombocytopenic Purpura
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CLINICAL_TRIALS trial_result · 2019-03-18Clinical Trial Update: Eltrombopag and the Bcl-extra-large (xL) Pathway in Idiopathic Thrombocytopenic Purpura (ITP) [Phase 2]
Phase 2 trial evaluating eltrombopag targeting the Bcl-xL pathway in idiopathic thrombocytopenic purpura (immune thrombocytopenia) completed…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Phase I Safety and Tolerability Study of Staphylococcal Protein A in Adult Patients With Chronic ITP [Phase 1]
Phase I safety and tolerability study of Staphylococcal Protein A in adults with chronic idiopathic thrombocytopenic purpura has terminated.
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CLINICAL_TRIALS withdrawal · 2018-07-17Clinical Trial Update: A Trial to Treat Patients With ITP Who Do Not Achieve a Durable Response to Rituxan Alone [Phase 2]
The Phase 2 trial evaluating treatment for Idiopathic Thrombocytopenic Purpura patients who do not have a durable response to Rituxan has be…
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: Phase 2, Parallel Group, Rollover Study of AKR-501 in Patients With ChronicITP Who Completed 28 Days of Study Treatment in Protocol 501-CL-003 [Phase 2]
Phase 2 rollover study of AKR-501 in chronic Idiopathic Thrombocytopenic Purpura (ITP); results posted for patients who completed 28 days of…
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: A Phase 3, Multicenter, Randomized, Double-blind,Active-controlled, Parallel-group Trial With an Open-labelExtension Phase to Evaluate the Efficacy and Safety of OralE5501 Versus Eltrombopag, in Adults With Chronic ImmuneThrombocytopenia (Idiopathic Thrombocytopenic Purpura) [Phase 3]
A Phase 3 randomized trial comparing oral E5501 to eltrombopag in adults with chronic immune thrombocytopenia (Idiopathic Thrombocytopenic P…
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Sirolimus for Autoimmune Disease of Blood Cells [Phase 1, Phase 2]
A phase 1/2 trial evaluating sirolimus for autoimmune blood cell disorders, including autoimmune pancytopenia and ALPS; the study is complet…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Study In Healthy Subjects To Evaluate The Photo-Irritant Potential Of Eltrombopag [Phase 1]
Phase 1 study in healthy subjects to assess the photo-irritant potential of eltrombopag.
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Relative Bioavailibilty for Pediatric Powder for Suspension (PfOS) Formulation and Food Effect [Phase 1]
A Phase 1 study from GlaxoSmithKline evaluated the relative bioavailability of a pediatric PfOS powder-for-suspension formulation and the ef…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Study Of Eltrombopag in Healthy Subjects and Volunteers With Mild, Moderate or Severe Hepatic Impairment [Phase 1]
Phase 1 clinical trial update evaluating eltrombopag in healthy subjects and volunteers with mild to severe hepatic impairment.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Study Of SB-497115 in Healthy Subjects and Subjects With Mild, Moderate or Severe Renal Impairment [Phase 1]
Phase 1 study evaluating SB-497115 in healthy subjects and subjects with varying renal function to characterize safety and pharmacokinetics,…
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Therapy of Adults Affected by Idiopathic Thrombocytopenic Purpura With Dexamethasone [Phase 2, Phase 3]
Clinical trial update on dexamethasone therapy for adults with idiopathic thrombocytopenic purpura (ITP) reported in Phase 2/Phase 3.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: EXTEND (Eltrombopag Extended Dosing Study) [Phase 3]
This clinical trial update reports the completion of the Phase 3 EXTEND study of eltrombopag (Promacta) for idiopathic thrombocytopenic purp…
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CLINICAL_TRIALS withdrawal · 2017-02-03Clinical Trial Update: Single Incision Versus Standard Laparoscopic Splenectomy [NA]
A clinical trial comparing single-incision versus standard laparoscopic splenectomy has been withdrawn.
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CLINICAL_TRIALS research · 2016-07-25Clinical Trial Update: Promacta Pregnancy Registry
This update notes the completion of GlaxoSmithKline's Promacta (eltrombopag) pregnancy registry, which monitors pregnancy outcomes in women …
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Ig NextGen 10% in Idiopathic Thrombocytopenic Purpura (ITP) Patients [Phase 3]
A Phase 3 clinical trial evaluating Ig NextGen 10% for idiopathic thrombocytopenic purpura (ITP) has completed.
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) [Phase 4]
Phase 4 trial comparing high-dose dexamethasone to conventional-dose prednisone for initial treatment of primary immune thrombocytopenia has…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Interventional Study in Adults With Immune Thrombocytopenia Purpura (ITP) Receiving Romiplostim [Phase 2]
A Phase 2 interventional trial in adults with immune thrombocytopenia purpura (idiopathic thrombocytopenic purpura) on romiplostim has compl…
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CLINICAL_TRIALS withdrawal · 2015-07-30Clinical Trial Update: MONICA-SC: A Study to Evaluate the Efficacy, Safety and Tolerability of Blisibimod (A-623) Administration in Subjects With ITP [Phase 2, Phase 3]
The MONICA-SC trial evaluating Blisibimod (A-623) for Immune Thrombocytopenic Purpura/Idiopathic Thrombocytopenic Purpura has been withdrawn…
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CLINICAL_TRIALS trial_result · 2015-04-09Clinical Trial Update: Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP) [Phase 1]
A phase 1 safety study of GMA161 in patients with idiopathic thrombocytopenic purpura has been terminated.
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Eltrombopag Phase III Study In Chinese Chronic ITP Patients [Phase 3]
Phase III trial update for eltrombopag in Chinese chronic idiopathic thrombocytopenic purpura (ITP) patients; results posted after completio…
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CLINICAL_TRIALS trial_result · 2015-01-01Clinical Trial Update: Study on Bone Marrow Morphology in Adults Receiving Romiplostim for Treatment of Thrombocytopenia Associated With Immune Thrombocytopenia Purpura (ITP) [Phase 4]
A Phase 4 clinical trial update assessing bone marrow morphology in adults treated with romiplostim for thrombocytopenia associated with idi…
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CLINICAL_TRIALS trial_result · 2014-10-31Clinical Trial Update: Efficacy and Safety Study of Eltrombopag in Pediatric Patients With Thrombocytopenia From Chronic Idiopathic Thrombocytopenic Purpura (ITP) [Phase 2]
Phase 2 trial assessing eltrombopag for efficacy and safety in pediatric patients with chronic idiopathic thrombocytopenic purpura (ITP).
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CLINICAL_TRIALS trial_result · 2014-10-22Clinical Trial Update: A Study Evaluating the Addition of MabThera (Rituximab) to Standard Treatment in Patients With Idiopathic Thrombocytopenic Purpura (ITP) [Phase 3]
Phase 3 study evaluating adding rituximab (MabThera) to standard treatment in idiopathic thrombocytopenic purpura (ITP) has completed with r…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: Study of a New Medication for Childhood Chronic Immune Thrombocytopenia (ITP), a Blood Disorder of Low Platelet Counts That Can Lead to Bruising Easily, Bleeding Gums, and/or Bleeding Inside the Body. [Phase 3]
Phase 3 trial in children with immune thrombocytopenia (Idiopathic Thrombocytopenic Purpura) evaluating a new medication has completed. Resu…
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CLINICAL_TRIALS withdrawal · 2014-07-28Clinical Trial Update: A Study to Investigate Belimumab for the Treatment of Chronic Immune Thrombocytopenia. [Phase 2]
A Phase 2 clinical trial evaluating belimumab for chronic immune thrombocytopenia was withdrawn.