Idiopathic Pulmonary Fibrosis
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis
A University of Virginia clinical trial is investigating quantitative CT and radiomic biomarkers to advance precision medicine in idiopathic…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Ongoing Monitoring of Vital Signs in Patients With Idiopathic Pulmonary Fibrosis Before and After Acute Exacerbation.
A Biosency-sponsored clinical trial is enrolling to monitor vital signs in patients with idiopathic pulmonary fibrosis before and after acut…
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF) [Phase 3]
Phase 3 study evaluating pamrevlumab for idiopathic pulmonary fibrosis has been terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Investigating Trends in Quality of Life in Patients With Idiopathic Pulmonary Fibrosis (IPF) Under Treatment With Nintedanib
Completed clinical trial evaluating trends in quality of life for patients with idiopathic pulmonary fibrosis treated with nintedanib; resul…
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: Efficacy of Steroid Pulse Therapy in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF) Admitted in ER [NA]
A completed clinical trial evaluating the efficacy of steroid pulse therapy for acute exacerbation of idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Clinical Genetics and Screening for Idiopathic Pulmonary Fibrosis
A clinical trial update for genetic screening in familial and idiopathic pulmonary fibrosis (NCT06521125); the study is not yet recruiting.
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: Effects of Pulmonary Diseases and Their Treatment on Cardiac Function
This clinical trial update describes a study evaluating how chronic pulmonary diseases and their treatments influence cardiac function, and …
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: The Effect of N115 on Coughing in IPF Patients [Phase 3]
Phase 3 trial of N115 in idiopathic pulmonary fibrosis patients has completed and results have been posted. The study evaluates the effect o…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of RSN0402 in Healthy Volunteers [Phase 1]
Phase 1 trial to evaluate safety, tolerability, and pharmacokinetics of RSN0402 in healthy volunteers is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Treatment of Idiopathic Pulmonary Fibrosis (IPF) by REGEND001 [Phase 1]
A Phase 1 trial evaluating REGEND001 for idiopathic pulmonary fibrosis has completed; the update confirms completion of the study but does n…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF) [NA]
This document reports a pilot clinical trial evaluating nitrate-rich beetroot juice supplementation in patients with idiopathic pulmonary fi…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: A Study to Test the Efficacy and Safety of Inhaled GB0139 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
Phase 2 trial of inhaled GB0139 in idiopathic pulmonary fibrosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis [Phase 3]
Phase 3 trial evaluating long-term safety and efficacy of PRM-151 (rhPTX-2) for idiopathic pulmonary fibrosis was terminated, and results ha…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 Following Single and Multiple Ascending Doses in Healthy Participants [Phase 1]
A Phase 1 study evaluated the safety, tolerability and pharmacokinetics of AZD5055 after single and multiple ascending doses in healthy part…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: University of Virginia Natural History Study
A University of Virginia natural history study (NCT04896138) is currently enrolling by invitation, focusing on interstitial lung diseases in…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis [NA]
Completed the structured exercise training program study in idiopathic pulmonary fibrosis to evaluate effects on breathlessness and quality …
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis [Phase 2]
A Phase 2 study evaluating the efficacy and safety of PLN-74809 in idiopathic pulmonary fibrosis has completed and posted results.
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EMA approval · 2024-04-25EMA Authorised: Pirfenidone axunio (previously Pirfenidone AET) (Pirfenidone) — Axunio Pharma GmbH
EMA authorised Pirfenidone axunio (Pirfenidone) for idiopathic pulmonary fibrosis under Axunio Pharma GmbH.
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: Adherence to Nintedanib Among Idiopathic Pulmonary Fibrosis Patients
Clinical trial update reporting adherence to nintedanib among patients with idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis [Phase 3]
Phase 3 trial evaluating rhPTX-2 (PRM-151) for idiopathic pulmonary fibrosis has been terminated with results posted.
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FDA approval · 2024-04-12FDA Approved: PIRFENIDONE — Supplemental Application (Cipla USA Inc.)
The FDA approved Cipla USA Inc.'s supplemental application for pirfenidone.
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FDA approval · 2024-04-12FDA Approved: PIRFENIDONE — Supplemental Application (ScieGen Pharmaceuticals, Inc.)
The FDA approved a supplemental application for pirfenidone submitted by ScieGen Pharmaceuticals, Inc., authorizing an update to the product…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Safety and Effectiveness of Nintedanib in Korean Patients
Clinical trial update on safety and effectiveness of nintedanib in Korean patients with idiopathic pulmonary fibrosis completed with results…
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: Telenursing and Remote Monitoring in Idiopathic Pulmonary Fibrosis (IPF) [NA]
A clinical trial update on telenursing and remote monitoring for Idiopathic Pulmonary Fibrosis has been terminated with results posted.
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FDA approval · 2023-12-14FDA Approved: PIRFENIDONE — Supplemental Application (ANI Pharmaceuticals, Inc.)
The FDA approved a supplemental application for pirfenidone filed by ANI Pharmaceuticals, Inc., updating the drug's approval status.